Reaction: Mirtazapine to 1 product

Reaction
Mirtazapine
DB00370
8-hydroxymirtazapine
DBMET00263
Reaction type
8-hydroxylation
Direction
Not Available
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Timmer CJ, Sitsen JM, Delbressine LP: Clinical pharmacokinetics of mirtazapine. Clin Pharmacokinet. 2000 Jun;38(6):461-74. doi: 10.2165/00003088-200038060-00001. [Article]
  2. Remeron tablets FDA label [File]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 1A2Not AvailableNot Availableimplied
Cytochrome P450 2D6Not AvailableNot Availableimplied