Reaction: Carbamazepine to 1 product

Reaction
Carbamazepine
DB00564
10,11-Epoxycarbamazepine
DBMET00291
Reaction type
10,11-epoxidation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
active
References
  1. Pharm KGB, carbamazepine pathway, pharmacokinetics [Link]
  2. Tegretol FDA label [Link]
  3. Pubchem: Dihodryxocarbamazepine (diol CBZ) [Link]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 3A5Not AvailableNot Availableconfirmed
Cytochrome P450 3A4Not AvailableNot Availableimplied
Cytochrome P450 2C8Not AvailableNot Availableimplied