Reaction: Aprepitant to 1 product

Reaction
Aprepitant
DB00673
(2R)-2-(4-fluorophenyl)-2-{[(5-oxo-2,5-dihydro-1H-1,2,4-triazol-3-yl)methyl]amino}acetic acid
DBMET00475
Reaction type
O-dealkylation
Direction
Not Available
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
Not Available
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 3A4Not AvailableNot Availableimplied
Cytochrome P450 1A2Not AvailableNot Availableimplied
Cytochrome P450 2C19Not AvailableNot Availableimplied