Reaction: Dexmethylphenidate to 1 product

Reaction
Dexmethylphenidate
DB06701
Ritalinic acid
DBMET00651
Reaction type
De-esterification
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Sun Z, Murry DJ, Sanghani SP, Davis WI, Kedishvili NY, Zou Q, Hurley TD, Bosron WF: Methylphenidate is stereoselectively hydrolyzed by human carboxylesterase CES1A1. J Pharmacol Exp Ther. 2004 Aug;310(2):469-76. doi: 10.1124/jpet.104.067116. Epub 2004 Apr 13. [Article]
  2. Dexmethylphenidate XR FDA Label [File]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
CarboxylesteraseNot AvailableNot Availableconfirmed