Reaction: Hydromorphone to 1 product

Reaction
Reaction type
glucuronidation
Direction
Major circulating metabolite?
Yes
Spontaneous?
No
Activity
active
References
  1. Abi-Aad KR, Derian A: Hydromorphone . [Article]
  2. Overholser BR, Foster DR: Opioid pharmacokinetic drug-drug interactions. Am J Manag Care. 2011 Sep;17 Suppl 11:S276-87. [Article]
  3. Gudin J: Opioid therapies and cytochrome p450 interactions. J Pain Symptom Manage. 2012 Dec;44(6 Suppl):S4-14. doi: 10.1016/j.jpainsymman.2012.08.013. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
UDP-glucuronosyltransferase 1-3Not AvailableNot Availableconfirmed
UDP-glucuronosyltransferase 2B7Not AvailableNot Availableconfirmed