Acyclovir sodiumProduct ingredient for Acyclovir
- Name
- Acyclovir sodium
- Drug Entry
- Acyclovir
Acyclovir is a nucleotide analog antiviral used to treat herpes simplex, Varicella zoster, herpes zoster, herpes labialis, and acute herpetic keratitis10,11,12,13,14,15. Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old.13
Acyclovir was granted FDA approval on 29 March 1982.12
- Accession Number
- DBSALT000004
- Structure
- Synonyms
- Aciclovir sodium
- UNII
- 927L42J563
- CAS Number
- 69657-51-8
- Weight
- Average: 247.1865
Monoisotopic: 247.068133886 - Chemical Formula
- C8H10N5NaO3
- InChI Key
- RMLUKZWYIKEASN-UHFFFAOYSA-M
- InChI
- InChI=1S/C8H11N5O3.Na/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14;/h3,14H,1-2,4H2,(H3,9,11,12,15);/q;+1/p-1
- IUPAC Name
- sodium 9-[(2-hydroxyethoxy)methyl]-2-imino-3,9-dihydro-2H-purin-6-olate
- SMILES
- [Na+].OCCOCN1C=NC2=C1NC(=N)N=C2[O-]
- External Links
- PubChem Compound
- 23665721
- ChemSpider
- 45865
- ChEMBL
- CHEMBL1200380
- Wikipedia
- Aciclovir
- Predicted Properties
Property Value Source Water Solubility 5.69 mg/mL ALOGPS logP -1.2 ALOGPS logP -2.5 Chemaxon logS -1.6 ALOGPS pKa (Strongest Acidic) -6.4 Chemaxon pKa (Strongest Basic) 20.4 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 7 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 118.58 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 76.2 m3·mol-1 Chemaxon Polarizability 21.16 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon