Promazine hydrochlorideProduct ingredient for Promazine
- Name
- Promazine hydrochloride
- Drug Entry
- Promazine
A phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic. It is currently not approved for use in the United States.
- Accession Number
- DBSALT000147
- Structure
- Synonyms
- Promazine HCl
- UNII
- U16EOR79U4
- CAS Number
- 53-60-1
- Weight
- Average: 320.88
Monoisotopic: 320.111397079 - Chemical Formula
- C17H21ClN2S
- InChI Key
- JIVSXRLRGOICGA-UHFFFAOYSA-N
- InChI
- InChI=1S/C17H20N2S.ClH/c1-18(2)12-7-13-19-14-8-3-5-10-16(14)20-17-11-6-4-9-15(17)19;/h3-6,8-11H,7,12-13H2,1-2H3;1H
- IUPAC Name
- dimethyl[3-(10H-phenothiazin-10-yl)propyl]amine hydrochloride
- SMILES
- Cl.CN(C)CCCN1C2=CC=CC=C2SC2=CC=CC=C12
- External Links
- PubChem Compound
- 5887
- ChemSpider
- 5676
- ChEBI
- 8460
- ChEMBL
- CHEMBL1200469
- Wikipedia
- Promazine
- Predicted Properties
Property Value Source Water Solubility 0.0207 mg/mL ALOGPS logP 4.63 ALOGPS logP 3.93 Chemaxon logS -4.1 ALOGPS pKa (Strongest Basic) 9.2 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 6.48 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 88.95 m3·mol-1 Chemaxon Polarizability 33.09 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon