Promazine hydrochlorideProduct ingredient for Promazine

Name
Promazine hydrochloride
Drug Entry
Promazine

A phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic. It is currently not approved for use in the United States.

Accession Number
DBSALT000147
Structure
Synonyms
Promazine HCl
UNII
U16EOR79U4
CAS Number
53-60-1
Weight
Average: 320.88
Monoisotopic: 320.111397079
Chemical Formula
C17H21ClN2S
InChI Key
JIVSXRLRGOICGA-UHFFFAOYSA-N
InChI
InChI=1S/C17H20N2S.ClH/c1-18(2)12-7-13-19-14-8-3-5-10-16(14)20-17-11-6-4-9-15(17)19;/h3-6,8-11H,7,12-13H2,1-2H3;1H
IUPAC Name
dimethyl[3-(10H-phenothiazin-10-yl)propyl]amine hydrochloride
SMILES
Cl.CN(C)CCCN1C2=CC=CC=C2SC2=CC=CC=C12
PubChem Compound
5887
ChemSpider
5676
ChEBI
8460
ChEMBL
CHEMBL1200469
Wikipedia
Promazine
Predicted Properties
PropertyValueSource
Water Solubility0.0207 mg/mLALOGPS
logP4.63ALOGPS
logP3.93Chemaxon
logS-4.1ALOGPS
pKa (Strongest Basic)9.2Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area6.48 Å2Chemaxon
Rotatable Bond Count4Chemaxon
Refractivity88.95 m3·mol-1Chemaxon
Polarizability33.09 Å3Chemaxon
Number of Rings3Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon