Tetraethylammonium iodideProduct ingredient for Tetraethylammonium
- Name
- Tetraethylammonium iodide
- Drug Entry
- Tetraethylammonium
Tetraethylammonium is an experimental drug with no approved indication or marketed formulation. The only marketed drug containing tetraethylammonium was a combination drug called Fosglutamina B6, but this drug has now been discontinued. As an experimental agent, tetraethylammonium is used in its salt forms such as tetraethylammonium chloride and tetraethylammonium bromide. Its mechanism of action is still being investigated, but it is known that tetraethylammonium blocks autonomic ganglia, calcium- and voltage- activated potassium channels, and nicotinic acetylcholine receptors. Because of its inhibitory actions at the autonomic ganglia, tetraethylammonium was thought to be a potential therapeutic vasodilator but serious toxic effects were found. The most common use of tetraethylammonium presently is as a pharmacological research agent that blocks selective potassium channels. Structurally, tetraethylammonium is positively charged due to its central quaternary ammonium.
- Accession Number
- DBSALT000177
- Structure
Structure for Tetraethylammonium iodide (DBSALT000177)
- Synonyms
- Not Available
- UNII
- 5YC77AN7EB
- CAS Number
- Not Available
- Weight
- Average: 257.1556
Monoisotopic: 257.064043065 - Chemical Formula
- C8H20IN
- InChI Key
- UQFSVBXCNGCBBW-UHFFFAOYSA-M
- InChI
- InChI=1S/C8H20N.HI/c1-5-9(6-2,7-3)8-4;/h5-8H2,1-4H3;1H/q+1;/p-1
- IUPAC Name
- tetraethylazanium iodide
- SMILES
- [I-].CC[N+](CC)(CC)CC
- External Links
- PubChem Compound
- 6225
- ChemSpider
- 5990
- Wikipedia
- Tetraethylammonium_iodide
- Predicted Properties
Property Value Source Water Solubility 0.0023 mg/mL ALOGPS logP -1.8 ALOGPS logP -2.5 Chemaxon logS -5 ALOGPS Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 0 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 0 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 54.9 m3·mol-1 Chemaxon Polarizability 17.32 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon