Alimemazine tartrateProduct ingredient for Alimemazine

Name
Alimemazine tartrate
Drug Entry
Alimemazine

A phenothiazine derivative that is used as an antipruritic.

Accession Number
DBSALT000183
Structure
Synonyms
Trimeprazine tartrate
UNII
362NW1LD6Z
CAS Number
4330-99-8
Weight
Average: 746.978
Monoisotopic: 746.317176732
Chemical Formula
C40H50N4O6S2
InChI Key
AJZJIYUOOJLBAU-RNKHSWPKSA-N
InChI
InChI=1S/2C18H22N2S.C4H6O6/c2*1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)21-18-11-7-5-9-16(18)20;5-1(3(7)8)2(6)4(9)10/h2*4-11,14H,12-13H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t;;1-,2-/m..0/s1
IUPAC Name
(2S,3S)-2,3-dihydroxybutanedioic acid; bis(dimethyl[2-methyl-3-(10H-phenothiazin-10-yl)propyl]amine)
SMILES
[H][C@@](O)(C(O)=O)[C@]([H])(O)C(O)=O.CC(CN(C)C)CN1C2=CC=CC=C2SC2=CC=CC=C12.CC(CN(C)C)CN1C2=CC=CC=C2SC2=CC=CC=C12
PubChem Compound
45358050
ChemSpider
23089504
Predicted Properties
PropertyValueSource
Water Solubility0.00835 mg/mLALOGPS
logP4.82ALOGPS
logP4.41Chemaxon
logS-4.6ALOGPS
pKa (Strongest Basic)9.42Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area6.48 Å2Chemaxon
Rotatable Bond Count11Chemaxon
Refractivity93.37 m3·mol-1Chemaxon
Polarizability34.37 Å3Chemaxon
Number of Rings6Chemaxon
Bioavailability0Chemaxon
Rule of FiveNoChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleYesChemaxon