Vilazodone hydrochlorideProduct ingredient for Vilazodone
- Name
- Vilazodone hydrochloride
- Drug Entry
- Vilazodone
Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptorsLabel,2. Vilazodone may also be associated with less sexual dysfunction and weight gain3. Vilazodone was given FDA approval on January 21, 20115,2.
- Accession Number
- DBSALT000187
- Structure
- Synonyms
- Vilazodone HCl
- UNII
- U8HTX2GK8J
- CAS Number
- 163521-08-2
- Weight
- Average: 477.986
Monoisotopic: 477.193152872 - Chemical Formula
- C26H28ClN5O2
- InChI Key
- RPZBRGFNBNQSOP-UHFFFAOYSA-N
- InChI
- InChI=1S/C26H27N5O2.ClH/c27-16-18-4-6-23-22(13-18)19(17-29-23)3-1-2-8-30-9-11-31(12-10-30)21-5-7-24-20(14-21)15-25(33-24)26(28)32;/h4-7,13-15,17,29H,1-3,8-12H2,(H2,28,32);1H
- IUPAC Name
- 5-{4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl}-1-benzofuran-2-carboxamide hydrochloride
- SMILES
- Cl.NC(=O)C1=CC2=CC(=CC=C2O1)N1CCN(CCCCC2=CNC3=C2C=C(C=C3)C#N)CC1
- External Links
- PubChem Compound
- 6918313
- ChemSpider
- 5293517
- ChEBI
- 70705
- ChEMBL
- CHEMBL1615374
- Wikipedia
- Vilazodone
- Predicted Properties
Property Value Source Water Solubility 0.123 mg/mL ALOGPS logP 4.21 ALOGPS logP 3.72 Chemaxon logS -3.6 ALOGPS pKa (Strongest Acidic) 14.19 Chemaxon pKa (Strongest Basic) 8.6 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 102.29 Å2 Chemaxon Rotatable Bond Count 7 Chemaxon Refractivity 129.71 m3·mol-1 Chemaxon Polarizability 49.91 Å3 Chemaxon Number of Rings 5 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon