Levobunolol hydrochlorideProduct ingredient for Levobunolol
- Name
- Levobunolol hydrochloride
- Drug Entry
- Levobunolol
A nonselective beta-adrenoceptor antagonist used in the treatment of glaucoma.
- Accession Number
- DBSALT000251
- Structure
Structure for Levobunolol hydrochloride (DBSALT000251)
- Synonyms
- Levobunolol HCl
- UNII
- O90S49LDHH
- CAS Number
- 27912-14-7
- Weight
- Average: 327.846
Monoisotopic: 327.16012141 - Chemical Formula
- C17H26ClNO3
- InChI Key
- DNTDOBSIBZKFCP-YDALLXLXSA-N
- InChI
- InChI=1S/C17H25NO3.ClH/c1-17(2,3)18-10-12(19)11-21-16-9-5-6-13-14(16)7-4-8-15(13)20;/h5-6,9,12,18-19H,4,7-8,10-11H2,1-3H3;1H/t12-;/m0./s1
- IUPAC Name
- 5-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalen-1-one hydrochloride
- SMILES
- Cl.[H][C@](O)(CNC(C)(C)C)COC1=CC=CC2=C1CCCC2=O
- External Links
- KEGG Compound
- C08228
- PubChem Compound
- 441415
- ChemSpider
- 390150
- ChEBI
- 6439
- ChEMBL
- CHEMBL1201177
- Wikipedia
- Levobunolol
- Predicted Properties
Property Value Source Water Solubility 0.251 mg/mL ALOGPS logP 2.06 ALOGPS logP 2.18 Chemaxon logS -3.1 ALOGPS pKa (Strongest Acidic) 14.09 Chemaxon pKa (Strongest Basic) 9.75 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 58.56 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 83.28 m3·mol-1 Chemaxon Polarizability 33.08 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon