Ciprofloxacin hydrochlorideProduct ingredient for Ciprofloxacin
- Name
- Ciprofloxacin hydrochloride
- Drug Entry
- Ciprofloxacin
Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics.9 It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.18,19,20,21,22,23,24,25,26
The first ciprofloxacin containing product was FDA approved on 22 October 1987.17
- Accession Number
- DBSALT000293
- Structure
Structure for Ciprofloxacin hydrochloride (DBSALT000293)
- Synonyms
- Ciprofloxacin HCl / Ciprofloxacin hydrochloride / Ciprofloxacin hydrochloride hydrate / Ciprofloxacin hydrochloride monohydrate
- External IDs
- DRG-0110 / RX710
- UNII
- 4BA73M5E37
- CAS Number
- 86393-32-0
- Weight
- Average: 385.82
Monoisotopic: 385.120462 - Chemical Formula
- C17H21ClFN3O4
- InChI Key
- ARPUHYJMCVWYCZ-UHFFFAOYSA-N
- InChI
- InChI=1S/C17H18FN3O3.ClH.H2O/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;;/h7-10,19H,1-6H2,(H,23,24);1H;1H2
- IUPAC Name
- 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrate hydrochloride
- SMILES
- O.Cl.OC(=O)C1=CN(C2CC2)C2=CC(N3CCNCC3)=C(F)C=C2C1=O
- External Links
- KEGG Drug
- D02216
- KEGG Compound
- C13993
- PubChem Compound
- 62999
- ChemSpider
- 56700
- ChEBI
- 59936
- ChEMBL
- CHEMBL4303345
- Wikipedia
- Ciprofloxacin
- Predicted Properties
Property Value Source Water Solubility 1.35 mg/mL ALOGPS logP -0.57 ALOGPS logP -0.86 Chemaxon logS -2.4 ALOGPS pKa (Strongest Acidic) 5.56 Chemaxon pKa (Strongest Basic) 8.77 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 72.88 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 87.94 m3·mol-1 Chemaxon Polarizability 33.33 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon