Minaprine dihydrochlorideProduct ingredient for Minaprine
- Name
- Minaprine dihydrochloride
- Drug Entry
- Minaprine
Minaprine is a psychotropic drug which has proved to be effective in the treatment of various depressive states. Like most antidepressants minaprine antagonizes behavioral despair. Minaprine is an amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and weight gain.
- Accession Number
- DBSALT000305
- Structure
Structure for Minaprine dihydrochloride (DBSALT000305)
- Synonyms
- Minaprine DiHCl
- UNII
- 82Y7NT6DFT
- CAS Number
- 25953-17-7
- Weight
- Average: 371.305
Monoisotopic: 370.132716824 - Chemical Formula
- C17H24Cl2N4O
- InChI Key
- GNUCGROXDZMCJI-UHFFFAOYSA-N
- InChI
- InChI=1S/C17H22N4O.2ClH/c1-14-13-16(15-5-3-2-4-6-15)19-20-17(14)18-7-8-21-9-11-22-12-10-21;;/h2-6,13H,7-12H2,1H3,(H,18,20);2*1H
- IUPAC Name
- N-(4-methyl-6-phenyl-2,3-dihydropyridazin-3-ylidene)-2-(morpholin-4-yl)ethan-1-amine dihydrochloride
- SMILES
- Cl.Cl.CC1=CC(=NNC1=NCCN1CCOCC1)C1=CC=CC=C1
- External Links
- PubChem Compound
- 33254
- ChemSpider
- 30722
- ChEBI
- 51040
- ChEMBL
- CHEMBL1364551
- Predicted Properties
Property Value Source Water Solubility 0.171 mg/mL ALOGPS logP 1.69 ALOGPS logP 1.91 Chemaxon logS -3.2 ALOGPS pKa (Strongest Acidic) 6.7 Chemaxon pKa (Strongest Basic) 11.01 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 49.22 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 99.72 m3·mol-1 Chemaxon Polarizability 34.5 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon