Fucidate sodiumProduct ingredient for Fusidic acid
- Name
- Fucidate sodium
- Drug Entry
- Fusidic acid
An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed) It acts by inhibiting translocation during protein synthesis. It is often used topically in creams and eyedrops but is available in systemic formulations including tablets and injections.
- Accession Number
- DBSALT000340
- Structure
- Synonyms
- Fusidate sodium / Fusidic acid, sodium salt / Sodium fusidate
- External IDs
- CEM-102 / ZN 6-NA
- UNII
- J7P3696BCQ
- CAS Number
- 751-94-0
- Weight
- Average: 538.701
Monoisotopic: 538.32703351 - Chemical Formula
- C31H47NaO6
- InChI Key
- HJHVQCXHVMGZNC-JCJNLNMISA-M
- InChI
- InChI=1S/C31H48O6.Na/c1-17(2)9-8-10-20(28(35)36)26-22-15-24(34)27-29(5)13-12-23(33)18(3)21(29)11-14-30(27,6)31(22,7)16-25(26)37-19(4)32;/h9,18,21-25,27,33-34H,8,10-16H2,1-7H3,(H,35,36);/q;+1/p-1/b26-20-;/t18-,21-,22-,23+,24+,25-,27-,29-,30-,31-;/m0./s1
- IUPAC Name
- sodium 2-[(1Z,2S,3aS,3bS,5aS,6S,7R,9aS,9bS,10R,11aR)-2-(acetyloxy)-7,10-dihydroxy-3a,3b,6,9a-tetramethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-ylidene]-6-methylhept-5-enoate
- SMILES
- [Na+].[H][C@@]12C[C@@H](O)[C@@]3([H])[C@@]4(C)CC[C@@H](O)[C@@H](C)[C@]4([H])CC[C@]3(C)[C@@]1(C)C[C@H](OC(C)=O)\C2=C(\CCC=C(C)C)C([O-])=O
- External Links
- Human Metabolome Database
- HMDB0015570
- KEGG Compound
- C06694
- PubChem Compound
- 3000226
- ChemSpider
- 2298842
- BindingDB
- 58924
- ChEBI
- 29013
- ChEMBL
- CHEMBL1256987
- PharmGKB
- PA164749648
- PDBe Ligand
- FUA
- Predicted Properties
Property Value Source Water Solubility 0.00437 mg/mL ALOGPS logP 4.57 ALOGPS logP 4.42 Chemaxon logS -5.1 ALOGPS pKa (Strongest Acidic) 4.46 Chemaxon pKa (Strongest Basic) -0.2 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 106.89 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 154.96 m3·mol-1 Chemaxon Polarizability 59.32 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon