Orphenadrine citrateProduct ingredient for Orphenadrine
- Name
- Orphenadrine citrate
- Drug Entry
- Orphenadrine
A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
- Accession Number
- DBSALT000400
- Structure
Structure for Orphenadrine citrate (DBSALT000400)
- Synonyms
- Orphenadrine (citrate)
- UNII
- X0A40N8I4S
- CAS Number
- 4682-36-4
- Weight
- Average: 461.5048
Monoisotopic: 461.204966973 - Chemical Formula
- C24H31NO8
- InChI Key
- MMMNTDFSPSQXJP-UHFFFAOYSA-N
- InChI
- InChI=1S/C18H23NO.C6H8O7/c1-15-9-7-8-12-17(15)18(20-14-13-19(2)3)16-10-5-4-6-11-16;7-3(8)1-6(13,5(11)12)2-4(9)10/h4-12,18H,13-14H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
- IUPAC Name
- 2-hydroxypropane-1,2,3-tricarboxylic acid; dimethyl({2-[(2-methylphenyl)(phenyl)methoxy]ethyl})amine
- SMILES
- OC(=O)CC(O)(CC(O)=O)C(O)=O.CN(C)CCOC(C1=CC=CC=C1)C1=CC=CC=C1C
- External Links
- PubChem Compound
- 20846
- ChemSpider
- 19620
- ChEBI
- 7790
- ChEMBL
- CHEMBL1200395
- Wikipedia
- Orphenadrine
- Predicted Properties
Property Value Source Water Solubility 0.03 mg/mL ALOGPS logP 3.5 ALOGPS logP 4.17 Chemaxon logS -4 ALOGPS pKa (Strongest Basic) 8.87 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 12.47 Å2 Chemaxon Rotatable Bond Count 11 Chemaxon Refractivity 84.97 m3·mol-1 Chemaxon Polarizability 31.8 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon