Edrophonium chlorideProduct ingredient for Edrophonium
- Name
- Edrophonium chloride
- Drug Entry
- Edrophonium
A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
- Accession Number
- DBSALT000475
- Structure
- Synonyms
- Not Available
- UNII
- QO611KSM5P
- CAS Number
- 116-38-1
- Weight
- Average: 201.693
Monoisotopic: 201.092041846 - Chemical Formula
- C10H16ClNO
- InChI Key
- BXKDSDJJOVIHMX-UHFFFAOYSA-N
- InChI
- InChI=1S/C10H15NO.ClH/c1-4-11(2,3)9-6-5-7-10(12)8-9;/h5-8H,4H2,1-3H3;1H
- IUPAC Name
- 3-(ethyldimethylazaniumyl)benzen-1-olate hydrochloride
- SMILES
- Cl.CC[N+](C)(C)C1=CC([O-])=CC=C1
- External Links
- PubChem Compound
- 8307
- ChemSpider
- 8006
- ChEBI
- 4759
- ChEMBL
- CHEMBL1128
- Wikipedia
- Edrophonium
- Predicted Properties
Property Value Source Water Solubility 0.0113 mg/mL ALOGPS logP -1.8 ALOGPS logP -1.9 Chemaxon logS -4.3 ALOGPS pKa (Strongest Acidic) 8.59 Chemaxon pKa (Strongest Basic) -6.1 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 23.06 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 72.96 m3·mol-1 Chemaxon Polarizability 18.8 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon