Trifluoperazine hydrochlorideProduct ingredient for Trifluoperazine
- Name
- Trifluoperazine hydrochloride
- Drug Entry
- Trifluoperazine
A phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic.
- Accession Number
- DBSALT000569
- Structure
Structure for Trifluoperazine hydrochloride (DBSALT000569)
- Synonyms
- Trifluoperazine HCl
- UNII
- 6P1Y2SNF5V
- CAS Number
- 440-17-5
- Weight
- Average: 480.417
Monoisotopic: 479.117658566 - Chemical Formula
- C21H26Cl2F3N3S
- InChI Key
- BXDAOUXDMHXPDI-UHFFFAOYSA-N
- InChI
- InChI=1S/C21H24F3N3S.2ClH/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24;;/h2-3,5-8,15H,4,9-14H2,1H3;2*1H
- IUPAC Name
- 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine dihydrochloride
- SMILES
- Cl.Cl.CN1CCN(CCCN2C3=CC=CC=C3SC3=C2C=C(C=C3)C(F)(F)F)CC1
- External Links
- PubChem Compound
- 66064
- ChemSpider
- 59454
- ChEBI
- 9710
- ChEMBL
- CHEMBL1257040
- Wikipedia
- Trifluoperazine
- Predicted Properties
Property Value Source Water Solubility 0.00876 mg/mL ALOGPS logP 4.87 ALOGPS logP 4.66 Chemaxon logS -4.7 ALOGPS pKa (Strongest Basic) 7.99 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 9.72 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 110.98 m3·mol-1 Chemaxon Polarizability 42.03 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon