Dipivefrin hydrochlorideProduct ingredient for Dipivefrin
- Name
- Dipivefrin hydrochloride
- Drug Entry
- Dipivefrin
Dipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. It is available as ophthalmic solution (eye drops).
- Accession Number
- DBSALT000626
- Structure
Structure for Dipivefrin hydrochloride (DBSALT000626)
- Synonyms
- Dipivefrin HCl
- UNII
- 5QTH9UHV0K
- CAS Number
- 64019-93-8
- Weight
- Average: 387.898
Monoisotopic: 387.181250782 - Chemical Formula
- C19H30ClNO5
- InChI Key
- VKFAUCPBMAGVRG-UHFFFAOYSA-N
- InChI
- InChI=1S/C19H29NO5.ClH/c1-18(2,3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)25-17(23)19(4,5)6;/h8-10,13,20-21H,11H2,1-7H3;1H
- IUPAC Name
- 2-[(2,2-dimethylpropanoyl)oxy]-5-[1-hydroxy-2-(methylamino)ethyl]phenyl 2,2-dimethylpropanoate hydrochloride
- SMILES
- Cl.CNCC(O)C1=CC(OC(=O)C(C)(C)C)=C(OC(=O)C(C)(C)C)C=C1
- External Links
- PubChem Compound
- 71486
- ChemSpider
- 64562
- ChEBI
- 4647
- ChEMBL
- CHEMBL1200833
- Wikipedia
- Dipivefrine
- Predicted Properties
Property Value Source Water Solubility 0.0582 mg/mL ALOGPS logP 3.17 ALOGPS logP 3.71 Chemaxon logS -3.8 ALOGPS pKa (Strongest Acidic) 14 Chemaxon pKa (Strongest Basic) 9.33 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 84.86 Å2 Chemaxon Rotatable Bond Count 9 Chemaxon Refractivity 94.94 m3·mol-1 Chemaxon Polarizability 38.79 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon