Fluvoxamine maleateProduct ingredient for Fluvoxamine
- Name
- Fluvoxamine maleate
- Drug Entry
- Fluvoxamine
Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor. Though it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder. Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised of approximately 35,000 patients. It was launched in the US in December 1994 and in Japan in June 1999. As of the end of 1995, more than 10 million patients worldwide have been treated with fluvoxamine.
- Accession Number
- DBSALT000879
- Structure
- Synonyms
- Fluvoxamine maleate
- External IDs
- DU23000 / SME 3110
- UNII
- 5LGN83G74V
- CAS Number
- 61718-82-9
- Weight
- Average: 434.412
Monoisotopic: 434.166471022 - Chemical Formula
- C19H25F3N2O6
- InChI Key
- LFMYNZPAVPMEGP-PIDGMYBPSA-N
- InChI
- InChI=1S/C15H21F3N2O2.C4H4O4/c1-21-10-3-2-4-14(20-22-11-9-19)12-5-7-13(8-6-12)15(16,17)18;5-3(6)1-2-4(7)8/h5-8H,2-4,9-11,19H2,1H3;1-2H,(H,5,6)(H,7,8)/b20-14+;2-1-
- IUPAC Name
- (2Z)-but-2-enedioic acid; (E)-(2-aminoethoxy)({5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene})amine
- SMILES
- OC(=O)\C=C/C(O)=O.COCCCC\C(=N/OCCN)C1=CC=C(C=C1)C(F)(F)F
- External Links
- PubChem Compound
- 9560989
- ChemSpider
- 7837210
- ChEBI
- 5139
- ChEMBL
- CHEMBL1409
- Wikipedia
- Fluvoxamine
- Predicted Properties
Property Value Source Water Solubility 0.00734 mg/mL ALOGPS logP 2.89 ALOGPS logP 2.8 Chemaxon logS -4.6 ALOGPS pKa (Strongest Basic) 8.86 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 56.84 Å2 Chemaxon Rotatable Bond Count 12 Chemaxon Refractivity 79.2 m3·mol-1 Chemaxon Polarizability 32.44 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon