Indecainide hydrochlorideProduct ingredient for Indecainide

Name
Indecainide hydrochloride
Drug Entry
Indecainide

Indecainide is a rarely used antidysrhythmic. Indecainide has local anesthetic activity and belongs to the membrane stabilizing (Class 1) group of antiarrhythmic agents; it has electrophysiologic effects characteristic of the IC class of antiarrhythmics.

Accession Number
DBSALT000880
Structure
Synonyms
Indecainide HCl
UNII
M76V0B96L5
CAS Number
73681-12-6
Weight
Average: 344.88
Monoisotopic: 344.1655411
Chemical Formula
C20H25ClN2O
InChI Key
NXNSCUZKMVYAJQ-UHFFFAOYSA-N
InChI
InChI=1S/C20H24N2O.ClH/c1-14(2)22-13-7-12-20(19(21)23)17-10-5-3-8-15(17)16-9-4-6-11-18(16)20;/h3-6,8-11,14,22H,7,12-13H2,1-2H3,(H2,21,23);1H
IUPAC Name
9-{3-[(propan-2-yl)amino]propyl}-9H-fluorene-9-carboxamide hydrochloride
SMILES
Cl.CC(C)NCCCC1(C(N)=O)C2=CC=CC=C2C2=C1C=CC=C2
PubChem Compound
52194
ChemSpider
47193
ChEBI
774292
ChEMBL
CHEMBL1200341
Predicted Properties
PropertyValueSource
Water Solubility0.000896 mg/mLALOGPS
logP3.24ALOGPS
logP3.26Chemaxon
logS-5.5ALOGPS
pKa (Strongest Acidic)16.51Chemaxon
pKa (Strongest Basic)10.4Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count2Chemaxon
Polar Surface Area55.12 Å2Chemaxon
Rotatable Bond Count6Chemaxon
Refractivity94.05 m3·mol-1Chemaxon
Polarizability35.59 Å3Chemaxon
Number of Rings3Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleYesChemaxon