Chloropyramine hydrochlorideProduct ingredient for Chloropyramine
- Name
- Chloropyramine hydrochloride
- Drug Entry
- Chloropyramine
Chlorpyramine is a first generation antihistamine used in Eastern European countries to treat bronchial asthma as well as allergice rhinitis, allergic conjunctivitis, and other allergic reactions. It is also indicated for Quincke's edema, allergic reactions to insect bites, food and drug allergies, and anaphylactic shock.
- Accession Number
- DBSALT000909
- Structure
Structure for Chloropyramine hydrochloride (DBSALT000909)
- Synonyms
- Chloropyramine HCl
- UNII
- FWA92Z14NN
- CAS Number
- 6170-42-9
- Weight
- Average: 326.27
Monoisotopic: 325.1112531 - Chemical Formula
- C16H21Cl2N3
- InChI Key
- VEYWWAGBHABATA-UHFFFAOYSA-N
- InChI
- InChI=1S/C16H20ClN3.ClH/c1-19(2)11-12-20(16-5-3-4-10-18-16)13-14-6-8-15(17)9-7-14;/h3-10H,11-13H2,1-2H3;1H
- IUPAC Name
- N-[(4-chlorophenyl)methyl]-N-[2-(dimethylamino)ethyl]pyridin-2-amine hydrochloride
- SMILES
- Cl.CN(C)CCN(CC1=CC=C(Cl)C=C1)C1=CC=CC=N1
- External Links
- PubChem Compound
- 25294
- ChemSpider
- 23627
- BindingDB
- 50015561
- ChEBI
- 661539
- ChEMBL
- CHEMBL550011
- Predicted Properties
Property Value Source Water Solubility 0.441 mg/mL ALOGPS logP 3.79 ALOGPS logP 3.81 Chemaxon logS -2.8 ALOGPS pKa (Strongest Basic) 8.76 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 19.37 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 86.08 m3·mol-1 Chemaxon Polarizability 32.5 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon