Antazoline sulfateProduct ingredient for Antazoline
- Name
- Antazoline sulfate
- Drug Entry
- Antazoline
Antazoline is a 1st generation antihistamine with anticholinergic activity. It is used to relieve nasal congestion. It is also formulated as eye drops with naphazoline to relieve allergic conjunctivitis.
- Accession Number
- DBSALT000910
- Structure
- Synonyms
- Not Available
- UNII
- 6T74I07212
- CAS Number
- 24359-81-7
- Weight
- Average: 363.43
Monoisotopic: 363.125277342 - Chemical Formula
- C17H21N3O4S
- InChI Key
- UWOSJBSLQYMGDL-UHFFFAOYSA-N
- InChI
- InChI=1S/C17H19N3.H2O4S/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16;1-5(2,3)4/h1-10H,11-14H2,(H,18,19);(H2,1,2,3,4)
- IUPAC Name
- N-benzyl-N-[(4,5-dihydro-1H-imidazol-2-yl)methyl]aniline; sulfuric acid
- SMILES
- OS(O)(=O)=O.C(N(CC1=CC=CC=C1)C1=CC=CC=C1)C1=NCCN1
- External Links
- Predicted Properties
Property Value Source Water Solubility 0.114 mg/mL ALOGPS logP 3.22 ALOGPS logP 2.88 Chemaxon logS -3.4 ALOGPS pKa (Strongest Basic) 9.24 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 27.63 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 82.89 m3·mol-1 Chemaxon Polarizability 30.5 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon