Antazoline sulfateProduct ingredient for Antazoline

Name
Antazoline sulfate
Drug Entry
Antazoline

Antazoline is a 1st generation antihistamine with anticholinergic activity. It is used to relieve nasal congestion. It is also formulated as eye drops with naphazoline to relieve allergic conjunctivitis.

Accession Number
DBSALT000910
Structure
Synonyms
Not Available
UNII
6T74I07212
CAS Number
24359-81-7
Weight
Average: 363.43
Monoisotopic: 363.125277342
Chemical Formula
C17H21N3O4S
InChI Key
UWOSJBSLQYMGDL-UHFFFAOYSA-N
InChI
InChI=1S/C17H19N3.H2O4S/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16;1-5(2,3)4/h1-10H,11-14H2,(H,18,19);(H2,1,2,3,4)
IUPAC Name
N-benzyl-N-[(4,5-dihydro-1H-imidazol-2-yl)methyl]aniline; sulfuric acid
SMILES
OS(O)(=O)=O.C(N(CC1=CC=CC=C1)C1=CC=CC=C1)C1=NCCN1
PubChem Compound
3084423
ChemSpider
2341485
Predicted Properties
PropertyValueSource
Water Solubility0.114 mg/mLALOGPS
logP3.22ALOGPS
logP2.88Chemaxon
logS-3.4ALOGPS
pKa (Strongest Basic)9.24Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count3Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area27.63 Å2Chemaxon
Rotatable Bond Count5Chemaxon
Refractivity82.89 m3·mol-1Chemaxon
Polarizability30.5 Å3Chemaxon
Number of Rings3Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon