Chlorothiazide sodiumProduct ingredient for Chlorothiazide
- Name
- Chlorothiazide sodium
- Drug Entry
- Chlorothiazide
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
- Accession Number
- DBSALT000926
- Structure
Structure for Chlorothiazide sodium (DBSALT000926)
- Synonyms
- Not Available
- UNII
- SN86FG7N2K
- CAS Number
- 7085-44-1
- Weight
- Average: 317.69
Monoisotopic: 316.93077 - Chemical Formula
- C7H5ClN3NaO4S2
- InChI Key
- CPIWHAFLBZQYLQ-UHFFFAOYSA-N
- InChI
- InChI=1S/C7H5ClN3O4S2.Na/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5;/h1-3H,(H2-,9,10,11,12,13);/q-1;+1
- IUPAC Name
- sodium 6-chloro-1,1-dioxo-7-sulfamoyl-2H-1lambda6,2,4-benzothiadiazin-2-ide
- SMILES
- [Na+].NS(=O)(=O)C1=C(Cl)C=C2N=C[N-]S(=O)(=O)C2=C1
- External Links
- PubChem Compound
- 16051990
- ChemSpider
- 21962
- ChEMBL
- CHEMBL1200616
- Wikipedia
- Chlorothiazide
- Predicted Properties
Property Value Source Water Solubility 0.693 mg/mL ALOGPS logP 0.14 ALOGPS logP -0.31 Chemaxon logS -2.7 ALOGPS pKa (Strongest Acidic) 6.49 Chemaxon pKa (Strongest Basic) -3.8 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 115.89 Å2 Chemaxon Rotatable Bond Count 1 Chemaxon Refractivity 62.14 m3·mol-1 Chemaxon Polarizability 24.06 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon