Mianserin hydrochlorideProduct ingredient for Mianserin
- Name
- Mianserin hydrochloride
- Drug Entry
- Mianserin
A tetracyclic compound with antidepressant effects. Mianserin was previously available internationally, however in most markets it has been phased out in favour of mirtazapine.
- Accession Number
- DBSALT000957
- Structure
Structure for Mianserin hydrochloride (DBSALT000957)
- Synonyms
- Mianserin HCl
- UNII
- 2X03TN217S
- CAS Number
- 21535-47-7
- Weight
- Average: 300.83
Monoisotopic: 300.1393264 - Chemical Formula
- C18H21ClN2
- InChI Key
- YNPFMWCWRVTGKJ-UHFFFAOYSA-N
- InChI
- InChI=1S/C18H20N2.ClH/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19;/h2-9,18H,10-13H2,1H3;1H
- IUPAC Name
- 5-methyl-2,5-diazatetracyclo[13.4.0.0^{2,7}.0^{8,13}]nonadeca-1(19),8,10,12,15,17-hexaene hydrochloride
- SMILES
- Cl.CN1CCN2C(C1)C1=CC=CC=C1CC1=CC=CC=C21
- External Links
- ChemSpider
- 61825
- BindingDB
- 31005
- ChEBI
- 31843
- ChEMBL
- CHEMBL544428
- Wikipedia
- Mianserin
- Predicted Properties
Property Value Source Water Solubility 0.232 mg/mL ALOGPS logP 3.52 ALOGPS logP 3.83 Chemaxon logS -3.1 ALOGPS pKa (Strongest Basic) 6.92 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 6.48 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 84.5 m3·mol-1 Chemaxon Polarizability 30.74 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon