Orphenadrine hydrochlorideProduct ingredient for Orphenadrine
- Name
- Orphenadrine hydrochloride
- Drug Entry
- Orphenadrine
A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
- Accession Number
- DBSALT001021
- Structure
- Synonyms
- Orphenadrine (chloride) / Orphenadrine HCl
- UNII
- UBY910DUXH
- CAS Number
- 341-69-5
- Weight
- Average: 305.85
Monoisotopic: 305.1546421 - Chemical Formula
- C18H24ClNO
- InChI Key
- UQZKYYIKWZOKKD-UHFFFAOYSA-N
- InChI
- InChI=1S/C18H23NO.ClH/c1-15-9-7-8-12-17(15)18(20-14-13-19(2)3)16-10-5-4-6-11-16;/h4-12,18H,13-14H2,1-3H3;1H
- IUPAC Name
- dimethyl({2-[(2-methylphenyl)(phenyl)methoxy]ethyl})amine hydrochloride
- SMILES
- Cl.CN(C)CCOC(C1=CC=CC=C1)C1=CC=CC=C1C
- External Links
- ChemSpider
- 9193
- ChEBI
- 60902
- ChEMBL
- CHEMBL1201023
- Wikipedia
- Orphenadrine
- Predicted Properties
Property Value Source Water Solubility 0.03 mg/mL ALOGPS logP 3.5 ALOGPS logP 4.17 Chemaxon logS -4 ALOGPS pKa (Strongest Basic) 8.87 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 12.47 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 84.97 m3·mol-1 Chemaxon Polarizability 31.8 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon