Isopropamide iodideProduct ingredient for Isopropamide

Show full entry for Isopropamide
Name
Isopropamide iodide
Drug Entry
Isopropamide

Isopropamide iodide is a long-acting quaternary anticholinergic drug. It is used in the treatment of peptic ulcer and other gastrointestinal disorders marked by hyperacidity and hypermotility.

See full entry for Isopropamide
Accession Number
DBSALT001023
Structure
Similar Structures
Synonyms
Not Available
UNII
E0KNA372SZ
CAS Number
71-81-8
Weight
Average: 480.434
Monoisotopic: 480.16376
Chemical Formula
C23H33IN2O
InChI Key
BFSMWENDZZIWPW-UHFFFAOYSA-N
InChI
InChI=1S/C23H32N2O.HI/c1-18(2)25(5,19(3)4)17-16-23(22(24)26,20-12-8-6-9-13-20)21-14-10-7-11-15-21;/h6-15,18-19H,16-17H2,1-5H3,(H-,24,26);1H
IUPAC Name
(3-carbamoyl-3,3-diphenylpropyl)(methyl)bis(propan-2-yl)azanium iodide
SMILES
[I-].CC(C)[N+](C)(CCC(C(N)=O)(C1=CC=CC=C1)C1=CC=CC=C1)C(C)C
ChemSpider
6047
ChEBI
6044
ChEMBL
CHEMBL1200347
Wikipedia
Isopropamide
Predicted Properties
PropertyValueSource
Water Solubility6.7e-05 mg/mLALOGPS
logP-0.17ALOGPS
logP0.14Chemaxon
logS-6.9ALOGPS
pKa (Strongest Acidic)16.31Chemaxon
pKa (Strongest Basic)-3.3Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count1Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area43.09 Å2Chemaxon
Rotatable Bond Count8Chemaxon
Refractivity120.74 m3·mol-1Chemaxon
Polarizability41.23 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon