Triflupromazine hydrochlorideProduct ingredient for Triflupromazine
- Name
- Triflupromazine hydrochloride
- Drug Entry
- Triflupromazine
A phenothiazine used as an antipsychotic agent and as an antiemetic.
- Accession Number
- DBSALT001039
- Structure
Structure for Triflupromazine hydrochloride (DBSALT001039)
- Synonyms
- Triflupromazine HCl
- UNII
- 9E75N4A5HM
- CAS Number
- 1098-60-8
- Weight
- Average: 388.88
Monoisotopic: 388.098782 - Chemical Formula
- C18H20ClF3N2S
- InChI Key
- FTNWXGFYRHWUKG-UHFFFAOYSA-N
- InChI
- InChI=1S/C18H19F3N2S.ClH/c1-22(2)10-5-11-23-14-6-3-4-7-16(14)24-17-9-8-13(12-15(17)23)18(19,20)21;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H
- IUPAC Name
- dimethyl({3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl})amine hydrochloride
- SMILES
- Cl.CN(C)CCCN1C2=CC=CC=C2SC2=C1C=C(C=C2)C(F)(F)F
- External Links
- ChemSpider
- 59459
- ChEBI
- 9712
- ChEMBL
- CHEMBL1201102
- Wikipedia
- Triflupromazine
- Predicted Properties
Property Value Source Water Solubility 0.0018 mg/mL ALOGPS logP 4.95 ALOGPS logP 4.81 Chemaxon logS -5.3 ALOGPS pKa (Strongest Basic) 9.2 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 6.48 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 94.93 m3·mol-1 Chemaxon Polarizability 34.6 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon