Mephentermine sulfateProduct ingredient for Mephentermine
- Name
- Mephentermine sulfate
- Drug Entry
- Mephentermine
A sympathomimetic agent with mainly indirect effects on adrenergic receptors. It is used to maintain blood pressure in hypotensive states, for example, following spinal anesthesia. Although the central stimulant effects of mephentermine are much less than those of amphetamine, its use may lead to amphetamine-type dependence. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1248)
- Accession Number
- DBSALT001074
- Structure
- Synonyms
- Not Available
- UNII
- 580655Z8RR
- CAS Number
- 1212-72-2
- Weight
- Average: 424.6
Monoisotopic: 424.239578821 - Chemical Formula
- C22H36N2O4S
- InChI Key
- DNKCFBJMFIUNRS-UHFFFAOYSA-N
- InChI
- InChI=1S/2C11H17N.H2O4S/c2*1-11(2,12-3)9-10-7-5-4-6-8-10;1-5(2,3)4/h2*4-8,12H,9H2,1-3H3;(H2,1,2,3,4)
- IUPAC Name
- bis(methyl(2-methyl-1-phenylpropan-2-yl)amine); sulfuric acid
- SMILES
- OS(O)(=O)=O.CNC(C)(C)CC1=CC=CC=C1.CNC(C)(C)CC1=CC=CC=C1
- External Links
- ChemSpider
- 64680
- ChEBI
- 6756
- ChEMBL
- CHEMBL3184799
- Wikipedia
- Mephentermine
- Predicted Properties
Property Value Source Water Solubility 0.457 mg/mL ALOGPS logP 2.54 ALOGPS logP 2.52 Chemaxon logS -2.6 ALOGPS pKa (Strongest Basic) 10.3 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 12.03 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 53.12 m3·mol-1 Chemaxon Polarizability 19.74 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon