Ranitidine bismuth citrateProduct ingredient for Ranitidine
- Name
- Ranitidine bismuth citrate
- Drug Entry
- Ranitidine
Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as cimetidine and famotidine. This drug helps to prevent and treat gastric-acid associated conditions, including ulcers, because of its ability to decrease gastric acid secretion.2,11 Ranitidine is often referred to as Zantac, and is available in various forms, including tablet, injection, and effervescent tablet preparations.11,14
The prevalence of GERD is thought to be 10-20% in western countries.4 Ranitidine has proven to be an effective treatment for relieving uncomfortable symptoms of gastric acid associated conditions and is therefore widely used in GERD and other gastric-acid related conditions.5,11
- Accession Number
- DBSALT001128
- Structure
Structure for Ranitidine bismuth citrate (DBSALT001128)
- Synonyms
- Not Available
- UNII
- 7AJ51I17KG
- CAS Number
- 128345-62-0
- Weight
- Average: 712.48
Monoisotopic: 712.12519 - Chemical Formula
- C19H27BiN4O10S
- InChI Key
- XAUTYMZTJWXZHZ-UHFFFAOYSA-K
- InChI
- InChI=1S/C13H22N4O3S.C6H8O7.Bi/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3;7-3(8)1-6(13,5(11)12)2-4(9)10;/h4-5,9,14-15H,6-8,10H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);/q;;+3/p-3
- IUPAC Name
- bismuth(3+) [1-({2-[({5-[(dimethylamino)methyl]furan-2-yl}methyl)sulfanyl]ethyl}amino)-2-nitroethenyl](methyl)amine 2-hydroxypropane-1,2,3-tricarboxylate
- SMILES
- [Bi+3].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O.CNC(NCCSCC1=CC=C(CN(C)C)O1)=C[N+]([O-])=O
- External Links
- ChemSpider
- 28530656
- ChEMBL
- CHEMBL2111286
- Wikipedia
- Bismuth_subcitrate
- Predicted Properties
Property Value Source Water Solubility 16.4 mg/mL ALOGPS logP 0.69 ALOGPS logP 0.99 Chemaxon logS -1.5 ALOGPS pKa (Strongest Basic) 7.8 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 83.58 Å2 Chemaxon Rotatable Bond Count 15 Chemaxon Refractivity 94.15 m3·mol-1 Chemaxon Polarizability 33.78 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon