Ceftibuten dihydrateProduct ingredient for Ceftibuten
- Name
- Ceftibuten dihydrate
- Drug Entry
- Ceftibuten
Ceftibuten is a third-generation cephalosporin antibiotic that is orally-administered. It is typically used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.
- Accession Number
- DBSALT001212
- Structure
Structure for Ceftibuten dihydrate (DBSALT001212)
- Synonyms
- Not Available
- UNII
- 62F4443RWP
- CAS Number
- 118081-34-8
- Weight
- Average: 446.45
Monoisotopic: 446.056605904 - Chemical Formula
- C15H18N4O8S2
- InChI Key
- SSWTVBYDDFPFAF-DKOGRLLHSA-N
- InChI
- InChI=1S/C15H14N4O6S2.2H2O/c16-15-17-7(5-27-15)6(1-2-9(20)21)11(22)18-10-12(23)19-8(14(24)25)3-4-26-13(10)19;;/h1,3,5,10,13H,2,4H2,(H2,16,17)(H,18,22)(H,20,21)(H,24,25);2*1H2/b6-1-;;/t10-,13-;;/m1../s1
- IUPAC Name
- (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid dihydrate
- SMILES
- O.O.NC1=NC(=CS1)C(=C\CC(O)=O)\C(=O)N[C@H]1[C@H]2SCC=C(N2C1=O)C(O)=O
- External Links
- ChemSpider
- 4445418
- ChEBI
- 34618
- Wikipedia
- Ceftibuten
- Predicted Properties
Property Value Source Water Solubility 0.0705 mg/mL ALOGPS logP 0.31 ALOGPS logP -1.4 Chemaxon logS -3.8 ALOGPS pKa (Strongest Acidic) 2.99 Chemaxon pKa (Strongest Basic) 4.69 Chemaxon Physiological Charge -2 Chemaxon Hydrogen Acceptor Count 8 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 162.92 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 97.02 m3·mol-1 Chemaxon Polarizability 37.8 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon