Antazoline phosphateProduct ingredient for Antazoline

Show full entry for Antazoline
Name
Antazoline phosphate
Drug Entry
Antazoline

Antazoline is a 1st generation antihistamine with anticholinergic activity. It is used to relieve nasal congestion. It is also formulated as eye drops with naphazoline to relieve allergic conjunctivitis.

See full entry for Antazoline
Accession Number
DBSALT001374
Structure
Similar Structures
Synonyms
Not Available
UNII
VPR5FPH326
CAS Number
154-68-7
Weight
Average: 363.354
Monoisotopic: 363.134793198
Chemical Formula
C17H22N3O4P
InChI Key
DUIGUKRYYAGJAF-UHFFFAOYSA-N
InChI
InChI=1S/C17H19N3.H3O4P/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16;1-5(2,3)4/h1-10H,11-14H2,(H,18,19);(H3,1,2,3,4)
IUPAC Name
N-benzyl-N-[(4,5-dihydro-1H-imidazol-2-yl)methyl]aniline; phosphoric acid
SMILES
OP(O)(O)=O.C(N(CC1=CC=CC=C1)C1=CC=CC=C1)C1=NCCN1
ChemSpider
139688
ChEMBL
CHEMBL1200550
Wikipedia
Antazoline
Predicted Properties
PropertyValueSource
Water Solubility0.114 mg/mLALOGPS
logP3.22ALOGPS
logP2.88Chemaxon
logS-3.4ALOGPS
pKa (Strongest Basic)9.24Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count3Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area27.63 Å2Chemaxon
Rotatable Bond Count5Chemaxon
Refractivity82.89 m3·mol-1Chemaxon
Polarizability30.5 Å3Chemaxon
Number of Rings3Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon