Sulfadiazine sodiumProduct ingredient for Sulfadiazine

Show full entry for Sulfadiazine
Name
Sulfadiazine sodium
Drug Entry
Sulfadiazine

One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.

See full entry for Sulfadiazine
Accession Number
DBSALT001400
Structure
Similar Structures
Synonyms
Not Available
UNII
84CS1P306F
CAS Number
547-32-0
Weight
Average: 272.26
Monoisotopic: 272.034391
Chemical Formula
C10H9N4NaO2S
InChI Key
JLDCNMJPBBKAHH-UHFFFAOYSA-N
InChI
InChI=1S/C10H9N4O2S.Na/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1
IUPAC Name
sodium 4-{[(pyrimidin-2-yl)azanidyl]sulfonyl}aniline
SMILES
[Na+].NC1=CC=C(C=C1)S(=O)(=O)[N-]C1=NC=CC=N1
ChemSpider
10565
ChEMBL
CHEMBL1200351
Wikipedia
Sulfadiazine
Predicted Properties
PropertyValueSource
Water Solubility4.12 mg/mLALOGPS
logP0.52ALOGPS
logP0.39Chemaxon
logS-1.8ALOGPS
pKa (Strongest Acidic)6.99Chemaxon
pKa (Strongest Basic)2.01Chemaxon
Physiological Charge-1Chemaxon
Hydrogen Acceptor Count6Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area95.17 Å2Chemaxon
Rotatable Bond Count2Chemaxon
Refractivity63.4 m3·mol-1Chemaxon
Polarizability22.87 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon