Penciclovir sodiumProduct ingredient for Penciclovir
- Name
- Penciclovir sodium
- Drug Entry
- Penciclovir
Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.
- Accession Number
- DBSALT001449
- Structure
- Synonyms
- Not Available
- UNII
- P06226385L
- CAS Number
- 97845-62-0
- Weight
- Average: 275.244
Monoisotopic: 275.09943361 - Chemical Formula
- C10H14N5NaO3
- InChI Key
- NMQFQBOIHUIALG-UHFFFAOYSA-M
- InChI
- InChI=1S/C10H15N5O3.Na/c11-10-13-8-7(9(18)14-10)12-5-15(8)2-1-6(3-16)4-17;/h5-6,16-17H,1-4H2,(H3,11,13,14,18);/q;+1/p-1
- IUPAC Name
- sodium 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6-oxo-6,9-dihydro-1H-purin-1-ide
- SMILES
- [Na+].NC1=NC2=C(N=CN2CCC(CO)CO)C(=O)[N-]1
- External Links
- ChemSpider
- 28524083
- ChEMBL
- CHEMBL2079793
- Wikipedia
- Penciclovir
- Predicted Properties
Property Value Source Water Solubility 12.1 mg/mL ALOGPS logP -1.4 ALOGPS logP -2.1 Chemaxon logS -1.4 ALOGPS pKa (Strongest Acidic) 10.17 Chemaxon pKa (Strongest Basic) 0.7 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 7 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 122.96 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 64.23 m3·mol-1 Chemaxon Polarizability 24.88 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon