Glucosamine sulfateProduct ingredient for Glucosamine
- Name
- Glucosamine sulfate
- Drug Entry
- Glucosamine
Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation.14 Treatment with chondroprotective drugs, such as glucosamine sulfate may offer additional benefits to nonsteroidal anti-inflammatory drugs treating the painful symptoms of OA. Glucosamine is commonly used over the counter as a treatment for arthritic joint pain, although its acceptance as a medical therapy varies due to contradictory and findings with unclear clinical significance during clinical trials.6,14 It is currently not approved as a prescription product by the FDA, but is widely available over the counter.
- Accession Number
- DBSALT001596
- Structure
Structure for Glucosamine sulfate (DBSALT001596)
- Synonyms
- Not Available
- UNII
- 1FW7WLR731
- CAS Number
- 14999-43-0
- Weight
- Average: 456.42
Monoisotopic: 456.126124764 - Chemical Formula
- C12H28N2O14S
- InChI Key
- WLNBMPZUVDTASE-HXIISURNSA-N
- InChI
- InChI=1S/2C6H13NO5.H2O4S/c2*7-3(1-8)5(11)6(12)4(10)2-9;1-5(2,3)4/h2*1,3-6,9-12H,2,7H2;(H2,1,2,3,4)/t2*3-,4+,5+,6+;/m00./s1
- IUPAC Name
- bis((2R,3R,4S,5R)-2-amino-3,4,5,6-tetrahydroxyhexanal); sulfuric acid
- SMILES
- OS(O)(=O)=O.N[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO.N[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO
- External Links
- ChemSpider
- 20100842
- Wikipedia
- Glucosamine
- Predicted Properties
Property Value Source Water Solubility 195.0 mg/mL ALOGPS logP -2.6 ALOGPS logP -3.7 Chemaxon logS 0.04 ALOGPS pKa (Strongest Acidic) 12.77 Chemaxon pKa (Strongest Basic) 6.86 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 5 Chemaxon Polar Surface Area 124.01 Å2 Chemaxon Rotatable Bond Count 10 Chemaxon Refractivity 39 m3·mol-1 Chemaxon Polarizability 16.65 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon