Cefdinir monohydrateProduct ingredient for Cefdinir
- Name
- Cefdinir monohydrate
- Drug Entry
- Cefdinir
Cefdinir, also known as Omnicef, is a semi-synthetic, broad-spectrum antibiotic belonging to the third generation of the cephalosporin class. It has been proven to be effective for the treatment of common bacterial infections in the ear, sinus, throat, lungs, and skin. Cefdinir was approved by the FDA in 1997 to treat a variety of mild to moderate infections and was initially marketed by Abbvie.6 Because of its chemical structure, it is effective against organisms that are resistant to first-line cephalosporin therapy due to the production of beta-lactamase enzymes.2,3
- Accession Number
- DBSALT001745
- Structure
Structure for Cefdinir monohydrate (DBSALT001745)
- Synonyms
- Not Available
- UNII
- 6E7SN358SE
- CAS Number
- 213978-34-8
- Weight
- Average: 413.42
Monoisotopic: 413.046375571 - Chemical Formula
- C14H15N5O6S2
- InChI Key
- QWUVJQSNISEEQI-KYIYMPJCSA-N
- InChI
- InChI=1S/C14H13N5O5S2.H2O/c1-2-5-3-25-12-8(11(21)19(12)9(5)13(22)23)17-10(20)7(18-24)6-4-26-14(15)16-6;/h2,4,8,12,24H,1,3H2,(H2,15,16)(H,17,20)(H,22,23);1H2/b18-7-;/t8-,12-;/m1./s1
- IUPAC Name
- (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(N-hydroxyimino)acetamido]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate
- SMILES
- O.NC1=NC(=CS1)C(=N\O)\C(=O)N[C@H]1[C@H]2SCC(C=C)=C(N2C1=O)C(O)=O
- External Links
- ChemSpider
- 10166233
- Predicted Properties
Property Value Source Water Solubility 0.0878 mg/mL ALOGPS logP 0.02 ALOGPS logP -1.7 Chemaxon logS -3.6 ALOGPS pKa (Strongest Acidic) 1.74 Chemaxon pKa (Strongest Basic) 7.45 Chemaxon Physiological Charge -2 Chemaxon Hydrogen Acceptor Count 8 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 158.21 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 94.34 m3·mol-1 Chemaxon Polarizability 36.12 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon