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Myasthenia gravis (MG) is an autoimmune disorder characterized by significant muscle weakness - particularly in the eye, throat, and extremities - caused by autoantibodies attacking the neuromuscular junction. The production of IgG autoantibodies against acetylcholine receptors (AChRs) is one of the more common pathophysiological mechanisms behind MG, and results in...
Approved
Investigational
Matched Description: … [L43190] A formulation for subcutaneous use that combines efgartigimod alfa and hyaluronidase was approved ... results in the destruction of these receptors and a reduction in electrical nerve impulses. ... autoimmune disorder characterized by significant muscle weakness - particularly in the eye, throat, and
Matched Categories: … Human Immunoglobulin G ... Antineoplastic and Immunomodulating Agents ... Immunoglobulin Fc Fragments …
Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ion exchange chromatography. IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population....
Approved
Investigational
Matched Synonyms: … Human immunoglobulin G ... Immunoglobulin G, human ... Immunoglobulin G (human) …
Matched Name: … Human immunoglobulin G
Matched Description: … Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human ... IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population ... The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and
Matched Categories: … Human Immunoglobulin G ... Immunoglobulin G ... Amino Acids, Peptides, and Proteins ... Immunoglobulin Isotypes …
Matched Products: … PASTEURISED HUMAN IMMUNOGLOBULIN GRIFOLS FOR INJECTION 160 mg/ml ... Octagam Immune Globulin (Human) ... GENIVIG HUMAN IMMUNGLOBULIN (PH 4) 5 G/100 ML IV INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET …
Esculin is found in barley. Vitamin C2 is generally considered a bioflavanoid, related to vitamin P esculin is a glucoside that naturally occurs in the horse chestnut (Aesculus hippocastanum), California Buckeye (Aesculus californica) and in daphnin (the dark green resin of Daphne mezereum). Esculin belongs to the family of Glycosyl...
Approved
Matched Description: … naturally occurs in the horse chestnut (Aesculus hippocastanum), California Buckeye (Aesculus californica) and
Highly purified sheep hyaluronidase for administration by injection into the vitreous of the eye.
Approved
Investigational
Matched Synonyms: … Hyaluronidase (ovine) ... Ovine hyaluronidase ... Hyaluronidase, ovine …
Matched Name: … Hyaluronidase (ovine) …
Matched Description: … Highly purified sheep hyaluronidase for administration by injection into the vitreous of the eye. …
Matched Categories: … Enzymes and Coenzymes …
Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection).
Investigational
Matched Synonyms: … PEGylated recombinant human hyaluronidase PH20 ... HUMAN HYALURONIDASE PH-20 (HYALURONOGLUCOSAMINIDASE PH-20, SPERM ADHESION MOLECULE 1, EC 3.2.1.35) PRECURSOR ... -METHOXY-, AMIDE WITH HYALURONOGLUCOSAMINIDASE (HUMAN ISOENZYME PH20) …
Matched Description: … Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And
Matched Categories: … Enzymes and Coenzymes …
Displaying all 5 drugs