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Displaying drugs 1 - 25 of 1928 in total
Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ion exchange chromatography. IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population....
Approved
Investigational
Matched Synonyms: … Human immunoglobulin G ... Immunoglobulin G, human ... Immunoglobulin G (human) …
Matched Name: … Human immunoglobulin G
Matched Description: … Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human ... IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population ... The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and
Matched Categories: … Human Immunoglobulin G ... Immunoglobulin G ... Amino Acids, Peptides, and Proteins ... Immunoglobulin Isotypes …
Matched Products: … PASTEURISED HUMAN IMMUNOGLOBULIN GRIFOLS FOR INJECTION 160 mg/ml ... Octagam Immune Globulin (Human) ... GENIVIG HUMAN IMMUNGLOBULIN (PH 4) 5 G/100 ML IV INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET …
Human thrombin is a sterile solution, pH 6.8-7.2, containing highly purified human thrombin for the activation of clotting. Thrombin is a highly specific serine protease encoded by the F2 gene that transforms soluble fibrinogen into insoluble fibrin. This transformation mimics the final coagulation cascade step which involves the clotting mass...
Approved
Matched Synonyms: … Thrombin human ... Thrombin (human) ... Thrombin Human Plasma-derived …
Matched Name: … Human thrombin …
Matched Description: … In particular, while human thrombin products are made from pooled human source plasma, recombinant thrombin ... is a human coagulation protein produced via recombinant DNA technology from a genetically modified Chinese ... achieves hemostasis and sealing of open tissues. …
Matched Mixtures name: … EVICEL Fibrin Sealant (Human) ... EVICEL Fibrin Sealant (Human) Solution, 50-90 mg/ml, 800-1200 IU/ml …
Matched Products: … Thrombin Human
Fibrinogen concentrate (human) is a hematological agent. It works by replacing a certain protein in the blood that helps with blood clotting. Fibrinogen (factor I) is a soluble plasma glycoprotein with a molecular weight of about 340 kDa. It is a physiological substrate for three enzymes: plasmin, factor XIIIa and...
Approved
Matched Synonyms: … Factor I human ... Fibrinogen human ... Fibrinogen (human) …
Matched Name: … Fibrinogen human
Matched Description: … Fibrinogen concentrate (human) is a hematological agent. ... It is a physiological substrate for three enzymes: plasmin, factor XIIIa and thrombin. ... acute bleeding episodes in patients with congenital fibrinogen deficiency, including afibrinogenemia and
Matched Mixtures name: … EVICEL Fibrin Sealant (Human) ... EVICEL Fibrin Sealant (Human) Solution, 50-90 mg/ml, 800-1200 IU/ml …
Matched Categories: … fibrinogen, human ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … Fibryga 1g Powder and Solvent for Solution for Injection or Infusion ... FIBRYGA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL ... FIBRYGA 1 g Pulver und Lösungsmittel zur Herstellung einer Injektions-/Infusionslösung …
Calcitonin was first discovered in isolated parathyroid tissue as a substance with a serum-calcium-lowering effect. It is constituted as a 32-amino acid single chain polypeptide structure that gets secreted as a regulatory agent in calcium-phosphorus metabolism. It is used as an alternative for people developing antibodies against salmon calcitonin.
Approved
Investigational
Matched Synonyms: … Calcitonin human ... Calcitonin (human) ... Calcitonin, human
Matched Name: … Human calcitonin …
Matched Categories: … Sex Hormones and Insulins ... calcitonin (human synthetic) …
Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Approved
Matched Synonyms: … Coagulation factor VIIa (recombinant) ... Coagulation factor VIIa (recombinant)-jncw …
Matched Name: … Coagulation factor VIIa Recombinant Human
Matched Description: … Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the ... Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … powder and solvent for solution for injection 2mg ... powder and solvent for solution for injection 1mg ... NOVOSEVEN 2MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis (MS), and was initially approved by the FDA in 1992. Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and significantly debilitating with a profound impact on the quality of life. Interferon...
Approved
Investigational
Matched Synonyms: … Interferon beta (recombinant) ... HUMAN INTERFERON BETA ... Interferon beta (human) …
Matched Name: … Human interferon beta …
Matched Description: … Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis ... (MS), and was initially approved by the FDA in 1992. ... [L12081] Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Factor XIII (human) is a heat-treated, lyophilized concentrate of coagulation factor XIII, an endogenous enzyme responsible for the crosslinking of fibrin and an essential component of the coagulation cascade [FDA Label]. For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key...
Approved
Investigational
Matched Synonyms: … Coagulation factor XIII, recombinant ... Factor XIII, human ... Human coagulation factor XIII …
Matched Name: … Factor XIII (human) …
Matched Description: … is a recombinant form of the A subunit of human coagulation factor XIII. ... recombinant DNA technology where the target protein is grown in yeast and then isolated [FDA Label]. ... Other drug products with similar structure and function to Factor XIII (human) include [DB09310], which …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Human chorionic gonadotropin (HCG), a polypeptide hormone produced by the human placenta. Endogenously produced HCG interacts with the LHCG receptor of the ovary and promotes the maintenance of the corpus luteum during the beginning of pregnancy. This allows the corpus luteum to continuously secrete the hormone progesterone during the first...
Approved
Vet approved
Matched Synonyms: … Human chorionic gonadotropin ... Human menopausal gonadotropin ... Human-chorionic gonadotropin …
Matched Name: … Chorionic Gonadotropin (Human) …
Matched Description: … Human chorionic gonadotropin (HCG), a polypeptide hormone produced by the human placenta. ... HCG is composed of an alpha and a beta sub-unit. ... Endogenously produced HCG interacts with the LHCG receptor of the ovary and promotes the maintenance …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Gonadotropins and Antigonadotropins ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Human Chorionic Gonadotrophin ... Powder and Solvent for Solution for Injection ... Choriomon 5000 IU powder and solvent for solution for injection …
A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Approved
Matched Synonyms: … Antithrombin III (human) ... Antithrombin III human ... Antithrombin III,human
Matched Name: … Antithrombin III human
Matched Description: … A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Human varicella-zoster immune globulin is a solvent/detergent-treated sterile liquid preparation of purified human immune globulin G (IgG) containing antibodies to varicella zoster virus (anti-VZV). It is prepared from pools of healthy human donors' plasma via anion-exchange column chromatography and was approved in 2012 under the name VariZIG to reduce the...
Approved
Matched Synonyms: … Varicella zoster immunoglobulin (human) ... Human herpesvirus 3 immune globulin ... Varicella zoster immune globulin human
Matched Name: … Human varicella-zoster immune globulin …
Matched Description: … human immune globulin G (IgG) containing antibodies to varicella zoster virus (anti-VZV). ... It is prepared from pools of healthy human donors' plasma via anion-exchange column chromatography and ... VariZIG to reduce the disease severity in high-risk patients who lack evidence of immunity to varicella and
Matched Categories: … Human Varicella Zoster Immune Globulins ... Fluids and Secretions ... Amino Acids, Peptides, and Proteins …
Matched Products: … Varicella-zoster Immune Globulin (human) …
The human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis. It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood vessel injury and stabilizing procoagulant factor VIII (FVIII). Exogenous sources of vWF...
Approved
Investigational
Matched Synonyms: … Human von willebrand factor ... Von willebrand factor (human) ... von Willebrand factor, human
Matched Name: … Von Willebrand factor human
Matched Description: … [L1878] A recombinant form of vWF, [vonicog alfa], is also available to enhance production and avoid ... The human vWF is used to manage and control bleeding episodes in patients with von Willebrand disease ... The human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... von Willebrand factor and coagulation factor VIII in combination …
Matched Products: … IMMUNATE 50 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... IMMUNATE 100 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Human vaccinia immune globulin (VIG) is a sterile solution containing the purified gamma globulin (IgG) fraction of plasma taken from healthy donors previously vaccinated with live vaccinia virus vaccine who possess high titers of anti-vaccinia virus antibody [FDA Label, A33814]. The IgG fraction is purified by the anion-exchange column chromatography...
Approved
Matched Synonyms: … Human vaccinia immune globulin ... Vaccinia Immune Globulin (Human) Intravenous ... Vaccinia immune globulin intravenous (human) …
Matched Name: … Human vaccinia virus immune globulin …
Matched Description: … Nevertheless, VIG by virtue of the way it is produced is a poorly characterized and highly variable human ... Human vaccinia immune globulin (VIG) is a sterile solution containing the purified gamma globulin (IgG ... The IgG fraction is purified by the anion-exchange column chromatography method and the solution is solvent …
Matched Categories: … Human Immunoglobulin G ... Immunoglobulin G ... Amino Acids, Peptides, and Proteins ... Immunoglobulin Isotypes …
Rabbit anti-thymocyte globulin. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of...
Approved
Matched Synonyms: … Anti-human thymocyte immunoglobulin, rabbit ... Rabbit anti-human thymocyte immunoglobulin ... Antithymocyte immunoglobulin
Matched Name: … Antithymocyte immunoglobulin (rabbit) …
Matched Categories: … Immunoglobulin G ... antithymocyte immunoglobulin (rabbit) ... Fluids and Secretions ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Human papillomavirus type 58 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 58. The vaccine is prepared from the purified...
Approved
Matched Synonyms: … Recombinant human papillomavirus type 58 L1 protein ... L1 protein, Human papillomavirus type 58 Vaccine …
Matched Name: … Human papillomavirus type 58 L1 capsid protein antigen …
Matched Description: … by Human Papillomavirus (HPV) type 58. ... *Saccharomyces cerevisiae* and self-assembled into VLPs. ... VLPs) of the major capsid (L1) protein of HPV Type 58 which are produced by separate fermentations in recombinant
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Matched Synonyms: … Recombinant human papillomavirus type 11 L1 protein ... L1 protein, Human papillomavirus type 11 Vaccine …
Matched Name: … Human papillomavirus type 11 L1 capsid protein antigen …
Matched Description: … Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human ... by Human Papillomavirus (HPV) types 6, 11, 16 and 18. ... 18, which are produced by separate fermentations in recombinant *Saccharomyces cerevisiae* and self-assembled …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Matched Categories: … Inactivated Human Papillomavirus Vaccine …
Infant botulism is a rare infectious disease occurring in infants in which Clostridium botulinum colonize the large intestine and being to produce botulinum neurotoxin directly in the gut. As these neurotoxins interfere with cholinergic nervous transmission, patients initially present with evident of loss of muscle tone (e.g. constipation, ptosis, feeding...
Approved
Matched Synonyms: … Botulism immune globulin IV human ... Botulism immune globulin intravenous (human) ... Human-derived botulism antitoxin antibodies …
Matched Name: … Human botulinum neurotoxin A/B immune globulin …
Matched Description: … [L39819,L39824] BabyBIG (human-derived botulism immunoglobulin) was approved for use by the FDA in ... from persons immunized with recombinant botulinum vaccine who have high titers of neutralizing antibodies ... Treatment and Prevention Program[L39829] and comprises IgG antibodies derived from pooled adult plasma …
Matched Categories: … Human Immunoglobulin G
A purified preparation of the enzyme recombinant human hyaluronidase. Hyaluronidase (human recombinant) (INN Vorhyaluronidase alfa) is produced by genetically engineered Chinese Hamster Ovary (CHO) cells containing a DNA plasmid encoding for a soluble fragment of human hyaluronidase (PH20). Hyaluronidase is an enzyme used to improve the absorption and dispersion of...
Approved
Investigational
Matched Synonyms: … Hyaluronidase human recombinant ... Hyaluronidase (human recombinant) ... Hyaluronidase recombinant human
Matched Name: … Hyaluronidase (human recombinant) …
Matched Description: … A purified preparation of the enzyme recombinant human hyaluronidase. ... Hyaluronidase (human recombinant) (INN Vorhyaluronidase alfa) is produced by genetically engineered Chinese ... [L13338] The action of hyaluronidase was first described in 1936, and named in 1939. …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs …
Matched Products: … Hyaluronidase ... HYLENEX Recombinant ... HYLENEX Recombinant Professional Sample …
Equine anti-thymocyte globulin is composed of purified gamma globulin containing primarily IgG against human thymus lymphocytes. It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen. The result is polyclonal IgG that...
Approved
Investigational
Matched Name: … Antilymphocyte immunoglobulin (horse) …
Matched Description: … in the type of antigen product used to produce immunoglobulin (thymocytes, peripheral T cells, etc.) ... Equine anti-thymocyte globulin is composed of purified gamma globulin containing primarily IgG against human ... It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune …
Matched Categories: … Immunoglobulin G ... antilymphocyte immunoglobulin (horse) ... Fluids and Secretions ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. Patients with cTTP...
Approved
Investigational
Matched Synonyms: … Recombinant human adamts13 ... Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs ... Metalloproteinase ADAMTS13 (human recombinant BAX930) …
Matched Description: … [A262071] Apadamtase alfa, sold under the brand name Adzynma (ADAMTS13, recombinant-krhn), was approved ... rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and ... Patients with cTTP have a severe deficiency of a plasma metalloproteinase called ADAMTS13 (a disintegrin and
Matched Categories: … Recombinant Proteins ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Approved
Investigational
Matched Name: … Human papillomavirus type 16 L1 capsid protein residues 2-471 antigen …
C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase inhibitor (rhC1INH), purified from the milk of transgenic rabbits. The primary function of endogenous C1INH is to regulate the activation of the complement and contact system pathways. It does this through inhibition of several target proteases within...
Approved
Investigational
Matched Synonyms: … Recombinant human C1-INH ... Recombinant human C1 inhibitor ... Recombinant human C1-inhibitor …
Matched Description: … C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase ... tPA and plasmin within the fibrinolytic pathway. ... Additionally, C4 and C2 cleavage occurs resulting in auto-activation of the complement system. …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system. Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved...
Approved
Matched Synonyms: … Recombinant human microplasmin ... Microplasmin (synthetic human) …
Matched Description: … Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced ... Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. ... by recombinant DNA technology in a Pichia pastoris expression system. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Approved
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with recombinant human fusion protein (MUCIN1 and Glutathione S Transferase …
Elotuzumab is a humanized IgG1 (Immunoglobulin G) monoclonal antibody indicated in combination with lenalidomide and dexamethasone for the treatment of patients with multiple myeloma who have received one to three prior therapies. Elotuzumab targets SLAMF7, also known as Signaling Lymphocytic Activation Molecule Family member 7, a cell surface glycoprotein. Elotuzumab...
Approved
Matched Synonyms: … Immunoglobulin G1, anti-(human protein CS1) (human-mouse HuLuc63 heavy chain), disulfide with human-mouse …
Matched Description: … Elotuzumab is a humanized IgG1 (Immunoglobulin G) monoclonal antibody indicated in combination with lenalidomide ... Elotuzumab is produced in NS0 cells by recombinant DNA technology. ... consists of the complementary determining regions (CDR) of the mouse antibody, MuLuc63, grafted onto human
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia.[L7634,L7637,L7640,L7643,L8519] Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and the release of glucose.[L7640,L7643] Glucagon was granted FDA...
Approved
Matched Synonyms: … Glucagon, human ... Glucagon recombinant ... Glucagon (recombinant dna origin) …
Matched Description: … diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and ... Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and
Matched Categories: … Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Displaying drugs 1 - 25 of 1928 in total