Displaying drugs 1 - 25 of 50 in total
Polyethylene glycol 400
Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain various derivatives and have various functions. Because many PEG types are hydrophilic, they are favorably used as enhancers of penetration, and used heavily in topical dermatological preparations. PEGs, along with their many nonionic derivatives, are...
Approved
Matched Synonyms: … Polyethylene glycol 400 ... Polyethylene glycol 8 ... PEG-400 …
Matched Name: … Polyethylene glycol 400 …
Matched Description: … [L1787] Polyethylene glycol 400 (PEG 400) is a low-molecular-weight grade of polyethylene glycol with ... Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain ... PEG "400" indicates that the average molecular weight of the specific PEG is 400 [L1788]. …
Matched Mixtures name: … Redness reliever and Lubricant ... Systane Day and Night Value Pack ... Systane Day and Night Value Pack …
Matched Products: … Foster and Thrive Dry Eye Relief …
Matched Name: … Polyethylene glycol 400 …
Matched Description: … [L1787] Polyethylene glycol 400 (PEG 400) is a low-molecular-weight grade of polyethylene glycol with ... Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain ... PEG "400" indicates that the average molecular weight of the specific PEG is 400 [L1788]. …
Matched Mixtures name: … Redness reliever and Lubricant ... Systane Day and Night Value Pack ... Systane Day and Night Value Pack …
Matched Products: … Foster and Thrive Dry Eye Relief …
Polyethylene glycol
Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage.[A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. Molecular weights of PEGs vary...
Approved
Vet approved
Matched Synonyms: … Polyethylene glycol 3350 ... Polyethylene glycol 4000 ... Polyethylene glycol 6000 …
Matched Name: … Polyethylene glycol …
Matched Description: … Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules ... [A190978] The most common preparations of PEGs include PEG 3350 and PEG 400. ... to make joining units of ethylene glycol by an ether linkage. …
Matched Mixtures name: … Polyethylene Glycol 3350 and Electrolytes ... Polyethylene Glycol-3350 and Electrolytes ... Polyethylene Glycol-3350 and Electrolytes with Flavor Pack …
Matched Categories: … Polyethylene Glycols ... Alimentary Tract and Metabolism …
Matched Products: … Polyethylene Glycol 3350 and Electrolytes ... POLYETHYLENE GLYCOL 3350 AND ELECTROLYTES With flavor packs ... Polyethylene Glycol-3350 …
Matched Name: … Polyethylene glycol …
Matched Description: … Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules ... [A190978] The most common preparations of PEGs include PEG 3350 and PEG 400. ... to make joining units of ethylene glycol by an ether linkage. …
Matched Mixtures name: … Polyethylene Glycol 3350 and Electrolytes ... Polyethylene Glycol-3350 and Electrolytes ... Polyethylene Glycol-3350 and Electrolytes with Flavor Pack …
Matched Categories: … Polyethylene Glycols ... Alimentary Tract and Metabolism …
Matched Products: … Polyethylene Glycol 3350 and Electrolytes ... POLYETHYLENE GLYCOL 3350 AND ELECTROLYTES With flavor packs ... Polyethylene Glycol-3350 …
Methoxy polyethylene glycol-epoetin beta
Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent (ESA) with a longer half-life than erythropoietin. ESA is used to increase synthesis of red blood cells to treat chronic kidney disease associated anemia.
Approved
Matched Name: … Methoxy polyethylene glycol-epoetin beta …
Matched Description: … Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent …
Matched Categories: … methoxy polyethylene glycol-epoetin beta ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent …
Matched Categories: … methoxy polyethylene glycol-epoetin beta ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Polidocanol
Polidocanol is a sclerosing agent indicated to treat uncomplicated spider veins (varicose veins ≤1 mm in diameter) and uncomplicated reticular veins (varicose veins 1 to 3 mm in diameter) in the lower extremity. It is marketed under the brand names Asclera and Varithena. The formula for Polidocanol has the structural...
Approved
Matched Synonyms: … Polyethylene glycol 450 lauryl ether ... Nonaethylene glycol monododecyl ether ... Nonaethylene glycol monolauryl ether …
Matched Description: … It is marketed under the brand names Asclera and Varithena. ... a sclerosing agent indicated to treat uncomplicated spider veins (varicose veins ≤1 mm in diameter) and ... has the structural formula C12H25(OCH2CH2)nOH, a mean extent of polymerization (n) of approximately 9 and …
Matched Categories: … Polyethylene Glycols …
Matched Description: … It is marketed under the brand names Asclera and Varithena. ... a sclerosing agent indicated to treat uncomplicated spider veins (varicose veins ≤1 mm in diameter) and ... has the structural formula C12H25(OCH2CH2)nOH, a mean extent of polymerization (n) of approximately 9 and …
Matched Categories: … Polyethylene Glycols …
Peginterferon beta-1a
Multiple Sclerosis (MS) is a chronic and inflammatory autoimmune disease of the central nervous system, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms between the age of 20 to 40, often the most productive years of...
Approved
Matched Synonyms: … Polyethylene glycol-interferon beta-1a …
Matched Description: … , disrupting communication between the brain and other parts of the body. ... Multiple Sclerosis (MS) is a chronic and inflammatory autoimmune disease of the central nervous system ... fatigue, gait changes, bowel or bladder dysfunction, abnormal muscle twitching, vision disturbance, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Description: … , disrupting communication between the brain and other parts of the body. ... Multiple Sclerosis (MS) is a chronic and inflammatory autoimmune disease of the central nervous system ... fatigue, gait changes, bowel or bladder dysfunction, abnormal muscle twitching, vision disturbance, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Nonoxynol-9
Nonoxynol-9 (N-9) is a typical surfactant used as a vaginal spermicide. Spermicides are locally acting non-hormonal contraceptives. When present in the vagina during intercourse, they immobilize/inactivate/damage and/or kill sperms without eliciting systemic effects. N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams,...
Approved
Withdrawn
Matched Synonyms: … P-Nonylphenyl polyethylene glycol ether ... Nonaethylene glycol nonylphenyl ether ... Nonaethylene glycol mono(nonylphenyl) ether …
Matched Description: … It is the most commonly used spermicidal contraceptive in the UK and the USA. ... N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels, foams and ... When present in the vagina during intercourse, they immobilize/inactivate/damage and/or kill sperms without …
Matched Categories: … Polyethylene Glycols …
Matched Description: … It is the most commonly used spermicidal contraceptive in the UK and the USA. ... N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels, foams and ... When present in the vagina during intercourse, they immobilize/inactivate/damage and/or kill sperms without …
Matched Categories: … Polyethylene Glycols …
Elapegademase
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … monomethoxypolyethylene glycol recombinant adenosine deaminase ... PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN AVERAGE OF 13 RESIDUES ARE SUBSTITUTED ON N.ALPHA..1ALANINE AND ... 356)-PEPTIDE, PRODUCED IN ESCHERICHIA COLI, SUBSTITUTED ON N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND …
Matched Description: … with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues ... as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues ... as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Damoctocog alfa pegol
In recent years, various extended half-life factor VIII and factor IX preparations have been studied and gained approval. In order to extend half-lives, techniques such as fusion to protein conjugates (Fc part of IgG1 or albumin), chemical modification (PEGylation), and protein sequence modification have been utilized. Also known as, BAY94-9027,...
Approved
Investigational
Matched Description: … glycol (PEG) to reduce the number of infusions necessary to prevent bleeds in patients diagnosed with ... known as, BAY94-9027, Damoctocog alfa pegol is a longer-acting Factor VIII therapy formulated with polyethylene ... and gained approval. …
Tetryzoline
Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral alpha (α)-adrenergic properties. Available since the 1950s, tetryzoline is a selective α1-receptor agonist that is used as an ocular and nasal decongestant. Tetryzoline is found in a wide array of over-the-counter eye drops, including the most...
Approved
Matched Description: … such as [povidone], [polyethylene glycol 400], [dextran], and [zinc sulfate]. ... scrutinized for possible drug overdose and toxicity from accidental ingestion. ... Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral …
Matched Mixtures name: … Up and Up Ultra Itchy Relief ... Redness reliever and Lubricant ... Seasonal itchy and Red eye relief …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Foster and Thrive Original Formula Eye Drops ... Walgreens Eye Drops Original 15mL and twin pack …
Matched Mixtures name: … Up and Up Ultra Itchy Relief ... Redness reliever and Lubricant ... Seasonal itchy and Red eye relief …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Foster and Thrive Original Formula Eye Drops ... Walgreens Eye Drops Original 15mL and twin pack …
Human immunoglobulin G
Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ion exchange chromatography. IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population....
Approved
Investigational
Matched Description: … The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ... Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human ... IVIg is used in the treatment of immunodeficiencies, as well as autoimmune and inflammatory disorders …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Potassium chloride
A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives.
The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of...
Approved
Withdrawn
Matched Description: … in fertilizers and explosives. ... that supply 100 mg or more of potassium per dosage unit, except for controlled-release dosage forms and ... crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and …
Matched Mixtures name: … Polyethylene Glycol 3350 and Electrolytes ... Polyethylene Glycol-3350 and Electrolytes ... Polyethylene Glycol-3350 and Electrolytes with Flavor Pack …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … INYECCION DE CLORURO DE POTASIO 400 MEQ./L. ... POTASSIUM CHLORIDE INJECTION - HIGHLY CONCENTRATED (400 mEq/l) …
Matched Mixtures name: … Polyethylene Glycol 3350 and Electrolytes ... Polyethylene Glycol-3350 and Electrolytes ... Polyethylene Glycol-3350 and Electrolytes with Flavor Pack …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … INYECCION DE CLORURO DE POTASIO 400 MEQ./L. ... POTASSIUM CHLORIDE INJECTION - HIGHLY CONCENTRATED (400 mEq/l) …
Nonacog beta pegol
Nonacog beta pegol is a recombinant coagulation factor IX derivative. It is produced without animal-derived materials and with an attached 40kDa polyethylene glycol (PEG) molecule for peptide activation by a site-directed glycoPEGylation. Once activated, the activation molecule with PEG is cleaved to leave the activated factor IX (Factor IXa). Nonacog...
Approved
Investigational
Matched Description: … It is produced without animal-derived materials and with an attached 40kDa polyethylene glycol (PEG) ... [A31496] Nonacog beta pegol was developed by Novo Nordisk and received its first global approval by the …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Certolizumab pegol
Certolizumab pegol is a pegylated monoclonal antibody against the tumor necrosis factor-alpha (TNF-alpha). It is formed with a humanized Fab fragment of 50 kDa, from an IgG 1 isotype, fused to a 40 kDa polyethylene glycol moiety replacing the Fc antibody region. The absence of the Fc region was ideated...
Approved
Matched Description: … glycol moiety replacing the Fc antibody region. ... A176585] It is formed with a humanized Fab fragment of 50 kDa, from an IgG 1 isotype, fused to a 40 kDa polyethylene ... [A176606] It was developed and manufactured by UCB Pharma, first FDA approved in 2008[L45018] and updated …
Matched Categories: … Polyethylene Glycols ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Polyethylene Glycols ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Avacincaptad pegol
Avacincaptad pegol is an RNA aptamer covalently bound to a branched polyethylene glycol (PEG) molecule. It was developed to treat an advanced form of age-related macular degeneration (AMD) called geographic atrophy (GA). AMD is the leading cause of vision loss in developed countries for people over 50 years old, with...
Approved
Investigational
Matched Description: … Avacincaptad pegol is an RNA aptamer covalently bound to a branched polyethylene glycol (PEG) molecule ... AMD eventually progresses to bilateral and irreversible loss of vision, whether or not the patients have ... This approval is based on the positive results obtained from 2 phase 3 clinical trials GATHER1 and GATHER2 …
Turoctocog alfa pegol
Turoctocog alfa pegol is a pegylated version of turoctocog alfa. Novo Nordisk's brand name Esperoct (turoctocog alfa pegol, N8-GP) was approved by the US FDA on February 19, 2019.
Fundamentally, the N8-GP moiety is identical to turoctocog alfa, a recombinant human clotting factor VIII (rFVIII) with a truncated B-domain made...
Approved
Matched Description: … 40-kDa polyethylene glycol (PEG) group to a specific _O_-glycan in the truncated B-domain of the general ... It was developed by Novo Nordisk and approved by the US FDA on October 16, 2013 [L1104]. ... The essential difference between turoctocog alfa and N8-GP, however, is the specific attachment of a …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Efmoroctocog alfa
Efmoroctocog alfa is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life compared with conventional factor VIII (FVIII) preparations, including recombinant FVIII (rFVIII) products such as DB13999 . It is an antihemorrhagic agent used in replacement therapy for patients with haemophilia A (congenital factor VIII deficiency). It...
Approved
Investigational
Matched Description: … glycol is covalently fused to the dimeric Fc domain of human immunoglobulin G1, a long-lived plasma ... commercially available rFVIII-Fc fusion protein (rFVIIIFc) where the conjugated molecule of rFVIII to polyethylene ... is purified endogenous Factor VIII from human pooled blood and contains both A- and B-subunits. …
Polyethylene glycol 300
Polyethylene glycol 300 (PEG 300) is a water-miscible polyether with an average molecular weight of 300 g/mol. It is a clear viscous liquid at room temperature with non-volatile, stable properties . Polyethylene glycols are widely used in biochemistry, structural biology, and medicine in addition to pharmaceutical and chemical industries. They...
Approved
Matched Name: … Polyethylene glycol 300 …
Matched Description: … Polyethylene glycol 300 (PEG 300) is a water-miscible polyether with an average molecular weight of 300 ... Polyethylene glycols are widely used in biochemistry, structural biology, and medicine in addition to ... pharmaceutical and chemical industries. …
Matched Mixtures name: … Lubricant and Redness Reliever …
Matched Description: … Polyethylene glycol 300 (PEG 300) is a water-miscible polyether with an average molecular weight of 300 ... Polyethylene glycols are widely used in biochemistry, structural biology, and medicine in addition to ... pharmaceutical and chemical industries. …
Matched Mixtures name: … Lubricant and Redness Reliever …
Tocofersolan
D-Alpha-tocopheryl polyethylene glycol 1000 succinate (Tocofersolan, Vedrop), has been developed in Europe as an orally bioavailable source of vitamin E in children suffering from cholestasis . Cholestasis is the reduction or stoppage of bile flow, either to impaired secretion by hepatocytes (liver cells) or obstruction , .
Tocofersolan is a...
Approved
Matched Synonyms: … -TOCOPHERYL POLYETHYLENE GLYCOL 1000 SUCCINATE ... VITAMIN E POLYETHYLENE GLYCOL SUCCINATE ... -TOCOPHEROL POLYETHYLENE GLYCOL 1000 SUCCINATE …
Matched Description: … Tocofersolan is a polyethylene glycol derivative of α-tocopherol and synthetic water-soluble version ... D-Alpha-tocopheryl polyethylene glycol 1000 succinate (Tocofersolan, Vedrop), has been developed in Europe ... capable of demonstrating antioxidant effects that make it a popular component to include in cosmetics and …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Description: … Tocofersolan is a polyethylene glycol derivative of α-tocopherol and synthetic water-soluble version ... D-Alpha-tocopheryl polyethylene glycol 1000 succinate (Tocofersolan, Vedrop), has been developed in Europe ... capable of demonstrating antioxidant effects that make it a popular component to include in cosmetics and …
Matched Categories: … Alimentary Tract and Metabolism …
Sodium bicarbonate
Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Approved
Matched Description: … powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and …
Matched Mixtures name: … Polyethylene Glycol 3350 and Electrolytes ... Polyethylene Glycol-3350 and Electrolytes ... Polyethylene Glycol-3350 and Electrolytes with Flavor Pack …
Matched Categories: … Antacids and Adsorbents ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Arm and Hammer Baking Soda …
Matched Mixtures name: … Polyethylene Glycol 3350 and Electrolytes ... Polyethylene Glycol-3350 and Electrolytes ... Polyethylene Glycol-3350 and Electrolytes with Flavor Pack …
Matched Categories: … Antacids and Adsorbents ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Arm and Hammer Baking Soda …
Vitamin E
In 1922, vitamin E was demonstrated to be an essential nutrient . Vitamin E is a term used to describe 8 different fat soluble tocopherols and tocotrienols, alpha-tocopherol being the most biologically active . Vitamin E acts as an antioxidant, protecting cell membranes from oxidative damage . The antioxidant effects...
Approved
Nutraceutical
Vet approved
Matched Description: … Vitamin E is a term used to describe 8 different fat soluble tocopherols and tocotrienols, alpha-tocopherol ... for use in the treatment of diseases causing bone loss, cardiovascular diseases, diabetes mellitus and ... Though this research is so far inconclusive, vitamin E remains a popular supplement and is generally …
Matched Mixtures name: … Vitamin E 400 Iu and Selenium 100mcg ... OB Complete 400 ... Vitamin E 400 + Selenium Cap …
Matched Categories: … Basic Ointments and Protectants ... Diet, Food, and Nutrition …
Matched Products: … E NAT 400 ... อี -400 ... E 400 Iu …
Matched Mixtures name: … Vitamin E 400 Iu and Selenium 100mcg ... OB Complete 400 ... Vitamin E 400 + Selenium Cap …
Matched Categories: … Basic Ointments and Protectants ... Diet, Food, and Nutrition …
Matched Products: … E NAT 400 ... อี -400 ... E 400 Iu …
Polysorbate 20
Polysorbate 20 is a polysorbate-type nonionic surfactant used in many commercial, household and pharmaceutical products. It is composed of 20 repeated units of polyethylene glycol via ethoxylation. Polysorbate 20 is a wetting agent in food products, as well as washing agent, stabilizer and solubilizer in labratory assays and industrial applications....
Approved
Matched Description: … It is composed of 20 repeated units of polyethylene glycol via ethoxylation. ... It is also an excipient that stabilizes emulsions and suspensions in pharmaceutical products and lubricant ... in labratory assays and industrial applications. …
Matched Categories: … Polyethylene Glycols …
Matched Categories: … Polyethylene Glycols …
Pegfilgrastim
Pegfilgrastim is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (G-CSF) analogue, filgrastim. The drug is approved for use to decrease the incidence of infection, as manifested by febrile neutropenia, in susceptible patients with with non-myeloid cancer receiving myelosuppressive anti-cancer treatment. Although the risk of developing febrile neutropenia...
Approved
Matched Description: … pharmacokinetic profile and conditions of use. ... than 20% in many readily used chemotherapy regimens,[A248855] infections pose risks of hospitalization and ... Pelmeg, Udenyca, Ziextenzo, Grasustek, Fylnetra, Stimufend) by Health Canada, European Union (EU), and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Rurioctocog alfa pegol
Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor. Factor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional factor VIII is associated with an elevated risk for excessive bleeding caused by spontaneous or secondary events like trauma...
Approved
Experimental
Matched Description: … The presence of the polyethylene glycol (PEG) moiety increases the plasma half-life of the drug, thereby ... Bleeding in joints is a common manifestation of hemophilia A, and bleeding episodes can be severe and ... alfa pegol aims to restore functional levels of factor VIII in patients with hemophilia A to manage and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 1500IU Powder and Solvent for Solution for Injection ... ADYNOVATE 2000IU Powder and Solvent for Solution for Injection ... ADYNOVATE 1000IU Powder and Solvent for Solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 1500IU Powder and Solvent for Solution for Injection ... ADYNOVATE 2000IU Powder and Solvent for Solution for Injection ... ADYNOVATE 1000IU Powder and Solvent for Solution for Injection …
Pegloticase
Pegloticase is a porcine recombinant PEGylated uricase indicated for the treatment of chronic gout in adult patients that do not respond to other types of therapies. Pegloticase has a similar activity to rasburicase, an enzyme that metabolizes uric acid to allantoin. In gout patients treated with pegloticase, the conversion of...
Approved
Investigational
Matched Description: … glycol (PEG) group. ... [L42425]
Pegloticase has a longer terminal elimination half-life thanks to the addition of a polyethylene ... of pegloticase and methotrexate. …
Matched Categories: … Enzymes and Coenzymes …
Matched Categories: … Enzymes and Coenzymes …
Eflapegrastim
Febrile neutropenia (FN), defined as the co-occurrence of fever (temperature > 38 ◦C) and severe neutropenia (ANC < 500 cells/mm3), is a potential side effect of myelosuppressive chemotherapy in which the patient develops an infection during a period of significant neutropenia. It typically develops during the first cycle of chemotherapy...
Approved
Investigational
Matched Description: … glycol linker. ... recombinant human G-CSF comprising a human G-CSF analog coupled to the Fc fragment of human IgG4 via a polyethylene ... risk of morbidity and mortality. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Displaying drugs 1 - 25 of 50 in total