This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Brand Names
- Vivotif
- Generic Name
- Typhoid Vaccine Live
- DrugBank Accession Number
- DB11050
- Background
Salmonella typhi Ty21a live antigen is a live attenuated vaccine for oral administration only. It contains the attenuated strain Salmonella typhi Ty21a. The vaccine prevents the development of typhoid fever, an acute, febrile enteric disease caused by Salmonella typhi by inducing a local immune response in the intestinal tract.
- Type
- Biotech
- Groups
- Approved
- Biologic Classification
- Vaccines
Attenuated - Synonyms
- Salmonella enterica subsp. enterica serovar typhi
- Salmonella typhi Ty21a live antigen
- Typhoid vaccine (salmonella typhi Ty21a)
- Typhoid Vaccine Live Ty21a
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Prevention of Disease caused by salmonella typhi •••••••••••• - Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAbacavir The therapeutic efficacy of Typhoid Vaccine Live can be decreased when used in combination with Abacavir. Abatacept The risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Abatacept. Acyclovir The therapeutic efficacy of Typhoid Vaccine Live can be decreased when used in combination with Acyclovir. Adalimumab The risk or severity of adverse effects can be increased when Adalimumab is combined with Typhoid Vaccine Live. Adefovir dipivoxil The therapeutic efficacy of Typhoid Vaccine Live can be decreased when used in combination with Adefovir dipivoxil. - Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Brand Name Prescription Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Vivotif Capsule, coated 6000000000 [CFU]/1 Oral A-S Medication Solutions 1992-03-16 Not applicable US 
Vivotif Capsule, delayed release 10000000000 [CFU] Oral Bavarian Nordic As 1993-01-01 Not applicable Canada 
Vivotif Capsule, coated 6000000000 [CFU]/1 Oral Emergent Travel Health Inc. 1992-03-16 Not applicable US Vivotif Capsule, coated 2 [CFU]/1[CFU] Oral A-S Medication Solutions 1992-03-16 Not applicable US Vivotif L Powder 10000000000 [CFU] Oral Berna Biotech Ltd 1997-11-01 2015-11-01 Canada
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 0MZI008M96
- CAS number
- Not Available
References
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 4 Active Not Recruiting Basic Science Typhoid Vaccination 1 4 Recruiting Basic Science Risk Reduction 1 4 Recruiting Basic Science Typhoid and/or Cholera Vaccination 1 4 Recruiting Prevention Cholera (Disorder) / Disease caused by Salmonella typhi / Vaccine Preventable Diseases 1 4 Unknown Status Prevention Healthy Volunteers (HV) 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Capsule, coated Oral 2 [CFU]/1[CFU] Capsule, coated Oral 6000000000 [CFU]/1 Capsule, delayed release Oral 10000000000 [CFU] Capsule, delayed release Oral 2000000000 U Capsule Oral Capsule, coated Oral Powder Oral 10000000000 [CFU] Capsule Oral 2000000000 CFU - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
Drug created at December 01, 2015 20:05 / Updated at April 17, 2024 06:33