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Displaying drugs 1 - 25 of 1466 in total
Parathyroid hormone (PTH) is a single-chain polypeptide composed of 84 amino acids. Available as Preotact, it is an identical form of human recombinant hormome which produced as a fusion protein undergoeing post-translational processing involving the cleavage of the OmpA leader sequence, leaving the mature protein as a single-chain 84 amino-acids...
Approved
Investigational
Matched Synonyms: … PTH(1-84) ... rPTH(1-84) ... rhPTH(1-84) …
Matched Description: … Parathyroid hormone (PTH) is a single-chain polypeptide composed of 84 amino acids. ... processing involving the cleavage of the OmpA leader sequence, leaving the mature protein as a single-chain 84
Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta...
Approved
Investigational
Matched Mixtures name: … VASOXEN PLUS 5/25 MG FILM TABLET, 84 ADET ... VASOXEN PLUS 5/12.5 MG FILM TABLET, 84 ADET ... NEBITENS PLUS 5/25MG FILM TABLET, TABLET, 84 ADET …
Matched Products: … BLOXER 5 MG TABLET, 84 ADET ... VASCURA 5 MG TABLET, 84 ADET ... VASOXEN 5 MG TABLET, 84 ADET …
Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Mixtures name: … ROSALIN 10/5 MG TABLET, 84 ADET ... ROSALIN 10/10 MG TABLET, 84 ADET ... ROSALIN 10/20 MG TABLET, 84 ADET …
Matched Products: … ROSUCOR 5 MG FILM TABLET, 84 ADET ... ROSUFIX 5 MG FILM TABLET, 84 ADET ... ROSUSTAR 5 MG FILM TABLET,84 ADET …
Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent. The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to drug-drug interactions. Olanzapine very closely resembles clozapine and only differs by...
Approved
Investigational
Matched Products: … APZET 5 MG FILM TABLET, 84 ADET ... APZET 10 MG FILM TABLET, 84 ADET ... OLLAFAX 5 MG FILM TABLET, 84 ADET …
Baricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. Overactive JAKs have been implicated in autoimmune disorders, such as rheumatoid arthritis. By inhibiting the actions of JAK1 and JAK2, baricitinib attenuates JAK-mediated inflammation and immune responses. Baricitinib was...
Approved
Investigational
Matched Products: … UNAMİTY 4 MG FİLM KAPLI TABLET, 84 ADET ... UNAMİTY 2 MG FİLM KAPLI TABLET, 84 ADET …
Gilteritinib, also known as ASP2215, is a small molecule part of the FLT3 tyrosine kinase inhibitors that presented a greater selectivity and potency when compared with other agents from this group. It is a pyrazinecarboxamide derivative that showed high selectivity to FLT3 preventing the c-Kit -driven myelosuppression observed in other...
Approved
Investigational
Matched Salts cas: … 1254053-84-3 …
Matched Products: … XOSPATA 40 MG FİLM KAPLI TABLET, 84 ADET …
Regorafenib is an orally-administered inhibitor of multiple kinases. It is used for the treatment of metastatic colorectal cancer, advanced gastrointestinal stromal tumours, and hepatocellular carcinoma. FDA approved on September 27, 2012. Approved use of Regorafenib was expanded to treat Hepatocellular Carcinoma in April 2017.
Approved
Matched Products: … STIVARGA 40 MG FILM KAPLI TABLET ,84 ADET …
Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with Ethinyl estradiol. Most recently, it was approved by both Health Canada and the FDA in combination with Estetrol as an oral contraceptive therapy.[L33199,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to...
Approved
Matched Iupac: … (1R,2R,4R,10R,11S,14S,15S,16S,18S,19S)-10,14-dimethylspiro[hexacyclo[9.8.0.0^{2,4}.0^{5,10}.0^{14,19} ... .0^{16,18}]nonadecane-15,2'-oxolan]-5-ene-5',7-dione …
Matched Products: … ZLYNDA 4 MG FİLM KAPLI TABLET, 84 ADET …
Miglustat, commonly marketed under the trade name Zavesca, is a drug used to treat Gaucher disease. It inhibits the enzyme glucosylceramide synthase, an essential enzyme for the synthesis of most glycosphingolipids. It is only used for patients who cannot be treated with enzyme replacement therapy with imiglucerase. Miglustat is now...
Approved
Matched Salts cas: … 210110-90-0
Matched Products: … ZAVESCA 100 MG KAPSUL, 84 ADET …
Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the...
Approved
Matched Mixtures name: … HARVONI 90 MG/400 MG FILM KAPLI TABLET, 84 ADET …
Matched Products: … SOVALDI 400 MG FILM KAPLI TABLET, 84 ADET …
Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to...
Approved
Investigational
Matched Mixtures name: … TELVIS PLUS 80/25 TABLET, 84 ADET ... TELMIDAY PLUS 80/25 MG TABLET, 84 ADET ... TENVIA PLUS 80/25 MG TABLET, 84 ADET …
Matched Products: … TELVIS 80 MG TABLET, 84 ADET ... TELZAP 40 MG TABLET, 84 ADET ... TELZAP 80 MG TABLET, 84 ADET …
Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's...
Approved
Investigational
Matched Mixtures name: … PHOCUSS 10 MG/20 MG FILM KAPLI TABLET, 84 ADET ... BERMAXIN 90/10/5 MG FILM TABLET ,FILM TABLET, 84 ADET …
Matched Products: … ALZIA 20 MG FILM TABLET, 84 ADET ... ALMENTA 15MG FILM TABLET, 84 ADET ... ALMENTA 20MG FILM TABLET, 84 ADET …
Strontium ranelate, a strontium (II) salt of ranelic acid, is a medication for osteoporosis. Some reports have shown that strontium ranelate can slow down the progression of osteoarthritis of the knee. This agent presents an atypical mechanism of action in which it increases deposition of new bone by osteoblasts and,...
Approved
Withdrawn
Matched Products: … RASBY 2 G ORAL SUSPANSIYON ICIN GRANUL ,84 PAKET …
Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to zoledronic acid, minodronic acid, and risedronic acid.[A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis.[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs. Ibandronate was granted FDA...
Approved
Investigational
Matched Products: … IBACUR 50 MG ŞASE, 84 ADET ... BONDKEM 50 MG FİLM KAPLI TABLET, 84 ADET ... BONDRONAT 50 MG FİLM KAPLI TABLET, 84 ADET …
Ramelteon is the first in a new class of sleep agents that selectively binds to the melatonin receptors in the suprachiasmatic nucleus (SCN). It is used for insomnia, particularly delayed sleep onset. Ramelteon has not been shown to produce dependence and has shown no potential for abuse.
Approved
Investigational
A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.
Approved
Investigational
A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
Approved
Ledipasvir is a direct acting antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Matched Mixtures name: … HARVONI 90 MG/400 MG FILM KAPLI TABLET, 84 ADET …
Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs. Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. Though its mechanism of action has not been clearly established, most of its actions appear to be associated with inhibition of prostaglandin synthesis via the...
Approved
Investigational
Tildrakizumab is a high-affinity, humanized, IgG1 κ antibody targeting interleukin 23 p19 that shows promise in the evolution of treatment strategy in chronic plaque psoriasis . The Food and Drug Administration (FDA) approved ILUMYA (tildrakizumab-asmn) for the treatment of adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy...
Approved
Investigational
Matched Description: … The approved recommended dosage of ILUMYA is a subcutaneous injection of 100 mg at Weeks 0, 4, and every …
A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985)....
Approved
Investigational
Lorazepam is a short-acting and rapidly cleared benzodiazepine used commonly as a sedative and anxiolytic. It was developed by DJ Richards, presented and marketed initially by Wyeth Pharmaceuticals in the USA in 1977. The first historic FDA label approval is reported in 1985 by the company Mutual Pharm.
Approved
Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are...
Approved
Nutraceutical
Matched Products: … YYUX Organic Liquid Vitamin D3 Drops For Baby 0-3 years 400 IU …
Antiarrhythmic agent pharmacologically similar to lidocaine. It may have some anticonvulsant properties.
Approved
Investigational
The World Health Organization declared smallpox, a contagious and sometimes fatal infectious disease, eradicated in 1980. However, there have been longstanding concerns that smallpox may be used as a bioweapon.[A35133,L3614] Tecovirimat is an antiviral drug that was identified via a high-throughput screen in 2002. It is effective against all orthopoxviruses,...
Approved
Investigational
Matched Iupac: … N-[(1R,2R,6S,7S,8S,10R)-3,5-dioxo-4-azatetracyclo[5.3.2.0^{2,6}.0^{8,10}]dodec-11-en-4-yl]-4-(trifluoromethyl …
Displaying drugs 1 - 25 of 1466 in total