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Displaying drugs 1 - 25 of 1693 in total

Omaveloxolone

Omaveloxolone (RTA-408) is a semisynthetic oleanane triterpenoid with antioxidant and anti-inflammatory properties.[A257534,A257539] Omaveloxolone acts as an activator of nuclear factor (erythroid-derived 2)-like 2 (Nrf2), a transcription factor that mitigates oxidative stress. In patients with Friedreich's ataxia, a genetic disease involving mitochondrial dysfunction, the Nrf2 pathway is impaired, and Nrf2 activity...
Approved
Investigational
Matched Synonyms: … Propanamide, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoro- …

Phloxine B

Phloxine B (commonly known simply as phloxine, also known as D&C RED NO. 28) is a color additive which is used both as an inactive ingredient to provide color to products, or as a colorant in dental disclosing tablets. These tablets allow patients to visualise areas where more brushing and...
Approved
Matched Synonyms: … D&C Red No. 28 …
Matched Description: … Phloxine B (commonly known simply as phloxine, also known as D&C RED NO. 28) is a color additive which …

Sunitinib

Sunitinib is a small-molecule multi-targeted receptor tyrosine kinase (RTK) inhibitor. On January 26, 2006, the agent was formally approved by the US FDA for the indications of treating renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST). For these purposes, sunitinib is generally available as an orally administered formulation....
Approved
Investigational
Matched Products: … SUTENT 28 ... SUTENT 50 MG KAPSUL, 28 ADET ... SUTENT 25 MG KAPSUL, 28 ADET …

Rosuvastatin

Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Mixtures name: … ROSALIN 10/5 MG TABLET, 28 ADET ... ROSALIN 10/10 MG TABLET, 28 ADET ... ROSALIN 10/20 MG TABLET, 28 ADET …
Matched Products: … ROSUCOR 5 MG FILM TABLET, 28 ADET ... ROSUFIX 5 MG FILM TABLET, 28 ADET ... ROSUSTAR 5 MG FILM TABLET,28 ADET …

Strontium ranelate

Strontium ranelate, a strontium (II) salt of ranelic acid, is a medication for osteoporosis. Some reports have shown that strontium ranelate can slow down the progression of osteoarthritis of the knee. This agent presents an atypical mechanism of action in which it increases deposition of new bone by osteoblasts and,...
Approved
Withdrawn
Matched Mixtures name: … STRODAY D3 2G/800 IU SAŞE , 28 SAŞE …
Matched Products: … DIOSS 2 G EFERVESAN TABLET, 28 ADET ... RASBY 2 G ORAL SUSPANSIYON ICIN GRANUL ,28 PAKET ... ONTIRAN 2 GR ORAL SUSPANSIYON ICIN GRANUL 28 POSET …

Atomoxetine

Atomoxetine is a selective norepinephrine (NE) reuptake inhibitor used for the treatment of attention deficit hyperactivity disorder (ADHD). Also known as the marketed product Strattera, atomoxetine is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve developmentally inappropriate symptoms associated with ADHD including distractibility, short attention...
Approved
Matched Products: … SETİNOX 5 MG KAPSÜL, 28 ADET ... FIXATOM 10 MG KAPSÜL, 28 ADET ... SETİNOX 80 MG KAPSÜL, 28 ADET …

Nebivolol

Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta...
Approved
Investigational
Matched Mixtures name: … VASOXEN PLUS 5/25 MG FILM TABLET, 28 ADET ... VASOXEN PLUS 5/12.5 MG FILM TABLET, 28 ADET ... NEBITENS PLUS 5/25MG FILM TABLET, TABLET, 28 ADET …
Matched Products: … VASCURA 5 MG TABLET, 28 ADET ... VASCURA 10 MG TABLET, 28 ADET ... BLOXER 5 MG TABLET, 28 ADET …

Trandolapril

Trandolapril is a non-sulhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to its biologically active diacid form, trandolaprilat, in the liver. Trandolaprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure...
Approved
Matched Mixtures name: … TARKA 180/2 FILM TABLET, 28 ADET ... VERACOMB MR 180/2 MG KAPSÜL, 28 ADET ... VERACOMB MR 240/4 MG KAPSÜL, 28 ADET …
Matched Products: … GOPTEN 2 MG KAPSUL, 28 ADET ... GOPTEN FORTE 4 MG KAPSUL, 28 ADET …

Guanfacine

Guanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension but is now indicated as an extended release tablet for the treatment of ADHD. Guanfacine was first described in the literature in 1974. Guanfacine was granted FDA approval on 27 October 1986.
Approved
Investigational
Matched Products: … GUAGO 1 MG UZATILMIŞ SALIMLI TABLET, 28 ADET ... GUAGO 2 MG UZATILMIŞ SALIMLI TABLET, 28 ADET ... GUAGO 3 MG UZATILMIŞ SALIMLI TABLET, 28 ADET …

Memantine

Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's...
Approved
Investigational
Matched Mixtures name: … DEZİRA COMBİ 10 MG/28 MG UZATILMIŞ SALIMLI SERT KAPSÜL, 28 ADET ... MEXIA XR 7 MG + 14 MG + 21 MG + 28 MG TEDAVIYE BAŞLAMA PAKETI ,28 UZATILMIŞ SALINIMLI MIKROPELLET KAPSÜL ... MEXIA XR 7 MG + 14 MG + 21 MG + 28 MG TEDAVIYE BAŞLAMA PAKETI ,28 UZATILMIŞ SALINIMLI MIKROPELLET KAPSÜL …
Matched Products: … ALZIA 10 MG FILM TABLET, 28 ADET ... ALZIA 20 MG FILM TABLET, 28 ADET ... ALMENTA 15MG FILM TABLET, 28 ADET …

Deferasirox

Deferasirox is an iron chelator and the first oral medication FDA approved for chronic iron overload in patients receiving long term blood transfusions.
Approved
Investigational
Matched Products: … CELACT 250 MG DAĞILABİLİR TABLET, 28 ADET ... CELACT 500 MG DAĞILABİLİR TABLET, 28 ADET ... CELACT 125 MG DAĞILABİLİR TABLET, 28 ADET …

Ethynodiol diacetate

A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive. Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug that has never been...
Approved
Matched Mixtures name: … Zovia 1/35E-28 ... Zovia 1/50E-28 ... Zovia 1/35E-28 …
Matched Products: … FEMULEN TABLET, 28 ADET …

Olanzapine

Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent. The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to drug-drug interactions. Olanzapine very closely resembles clozapine and only differs by...
Approved
Investigational
Matched Products: … ZOLAPINE 5 MG TABLET, 28 ADET ... ZOLAPINE 10 MG TABLET, 28 ADET ... ZOLAPINE 15 MG TABLET, 28 ADET …

Teriflunomide

Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. It is marketed under the name Aubagio® and is indicated for the treatment of multiple sclerosis, specifically relapsing forms. The FDA label states an important warning about the risk of hepatoxicity and...
Approved
Matched Products: … AVORAN 14 MG FİLM KAPLI TABLET, 28 ADET ... BAUDA 14 MG FİLM KAPLI TABLET , 28 ADET ... AUBAGIO 14 MG FILM KAPLI TABLET, 28 ADET …

Vildagliptin

Vildagliptin (LAF237) is an orally active antihyperglycemic agent that selectively inhibits the dipeptidyl peptidase-4 (DPP-4) enzyme. It is used to manage type II diabetes mellitus, where GLP-1 secretion and insulinotropic effects are impaired. By inhibiting DPP-4, vildagliptin prevents the degradation of glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP),...
Approved
Investigational
Matched Products: … GLIPTA 50 MG TABLET, 28 ADET ... DIYATIX 50 MG TABLET, 28 ADET ... TAGLİN 50 MG TABLET, 28 ADET …

Citalopram

Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs.[A261316,A14720] Citalopram enhances serotonergic transmission through the...
Approved
Matched Products: … ATOPRAN 20 MG FILM TABLET, 28 ADET ... ATOPRAN 40 MG FILM TABLET, 28 ADET ... LAIRA 10 MG FILM TABLET, 28 ADET …

Sertindole

Sertindole, a neuroleptic, is one of the newer antipsychotic medications available. Serdolect is developed by the Danish pharmaceutical company H. Lundbeck. It is a phenylindole derivative used in the treatment of schizophrenia. It was first marketed in 1996 in several European countries before being withdrawn two years later because of...
Approved
Investigational
Withdrawn
Matched Products: … SERDOLECT 12 MG FILM KAPLI TABLET, 28 ADET ... SERDOLECT 16 MG FILM KAPLI TABLET, 28 ADET ... SERDOLECT 20 MG FILM KAPLI TABLET, 28 ADET …

Paroxetine

Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others. It was approved by the FDA in the early 1990s and marketed by SmithKline...
Approved
Investigational
Matched Products: … PALUXON 20 MG FİLM TABLET, 28 ADET ... PALUXON 40 MG FİLM TABLET, 28 ADET ... PAXIL 20 MG FILM TABLET, 28 ADET …

Cilazapril

Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. It belongs to the angiotensin-converting enzyme inhibitors (ACE inhibitors) class of drugs. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. It is branded as Inhibace in Canada and...
Approved
Matched Mixtures name: … INHIBACE PLUS 5 MG TABLET, 28 ADET ... İNHİBACE PLUS 5 MG/12,5 MG FILM KAPLI TABLET, 28 ADET …
Matched Products: … INHIBACE 5 MG FİLM KAPLI TABLET, 28 ADET ... INHIBACE 2.5 MG FİLM KAPLI TABLET, 28 ADET …

Telmisartan

Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to...
Approved
Investigational
Matched Mixtures name: … TELVIS PLUS 80/25 TABLET, 28 ADET ... TWYNSTA 80/5 MG TABLET, 28 ADET ... TWYNSTA 80/10 MG TABLET, 28 ADET …
Matched Products: … TELPRES 80 MG TABLET, 28 ADET ... TELORA 40 MG TABLET, 28 ADET ... TELORA 80 MG TABLET, 28 ADET …

Raloxifene

Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific effects distinct from estradiol, raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM....
Approved
Investigational
Matched Products: … EVISTA 60 MG TABLET, 28 ADET ... ROXIMAX 60 MG FİLM TABLET, 28 ADET ... RALIEN 60 MG FILM KAPLI TABLET, 28 ADET …

Dalfampridine

Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. This is the first drug that was specifically approved to help with mobility in these patients. FDA approved on January 22, 2010.
Approved
Matched Products: … HALFPRİN 10 MG UZATILMIŞ SALIMLI TABLET, 28 ADET ... FAMPYRA 10 MG UZATILMIŞ SALIMLI TABLET ,TABLET, 28 ADET ... Famprimes 10 mg Uzatılmış Salımlı Tablet, 28 ADET …

Axitinib

Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3). Through this mechanism of action, axitinib blocks angiogenesis, tumour growth and metastases. It is reported to exhibit potency that is 50-450 times higher than that of the first generation...
Approved
Investigational
Matched Products: … INLYTA 3 MG FİLM KAPLI TABLET, 28 ADET ... INLYTA 7 MG FİLM KAPLI TABLET, 28 ADET ... INLYTA 1MG FILM KAPLI TABLET, TABLET, 28 ADET …

Vericiguat

Vericiguat is a direct stimulator of soluble guanylate cyclase (sGC) used in the management of systolic heart failure to reduce mortality and hospitalizations. A key component of the NO-sGC-cGMP signaling pathway that helps to regulate the cardiovascular system, sGC enzymes are intracellular enzymes found in vascular smooth muscle cells (amongst...
Approved
Investigational
Matched Products: … VERQUVO 2,5 MG FİLM KAPLI TABLET , 28 ADET ... VERQUVO 5 MG FİLM KAPLI TABLET , 28 ADET ... VERQUVO 10 MG FİLM KAPLI TABLET , 28 ADET …

Brigatinib

Brigatinib, originally named AP26113, is a reversible dual inhibitor of anaplastic lymphoma kinase (ALK) and epidermal growth factor receptor (EGFR). It presents selectivity against the mutant forms of EGFR compared to the wild-type. It also exhibits selectivity against 9 different Crizotinib-resistant mutants of the EML4-ALK fusion gene, which is a...
Approved
Investigational
Matched Description: … Ariad Pharmaceuticals, a subsidiary of Takeda Pharmaceutical Company Limited, and FDA-approved on April 28 …
Matched Products: … ALUNBRİG 30 MG FİLM KAPLI TABLET, 28 ADET ... ALUNBRİG 90 MG FİLM KAPLI TABLET, 28 ADET ... ALUNBRİG 180 MG FİLM KAPLI TABLET, 28 ADET …
Displaying drugs 1 - 25 of 1693 in total