NAV

Aminopromazine

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Aminopromazine
DrugBank Accession Number
DB15596
Background

Not Available

Type
Small Molecule
Groups
Experimental, Vet approved
Structure
3D
Similar Structures
Weight
Average: 327.49
Monoisotopic: 327.176918991
Chemical Formula
C19H25N3S
Synonyms
  • Aminopromazina
  • Aminopromazine
  • Aminopromazinum
  • Proquamezine
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Product Ingredients
IngredientUNIICASInChI Key
Aminopromazine hydrochlorideLFQ7A5UU2218704-89-7ISZDANQLTTVSKO-UHFFFAOYSA-N

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
S9SDD93U5U
CAS number
58-37-7
InChI Key
YZQNFFLGIYEXMM-UHFFFAOYSA-N
InChI
InChI=1S/C19H25N3S/c1-20(2)13-15(21(3)4)14-22-16-9-5-7-11-18(16)23-19-12-8-6-10-17(19)22/h5-12,15H,13-14H2,1-4H3
IUPAC Name
[1-(dimethylamino)-3-(10H-phenothiazin-10-yl)propan-2-yl]dimethylamine
SMILES
CN(C)CC(CN1C2=CC=CC=C2SC2=C1C=CC=C2)N(C)C

References

General References
Not Available
ChemSpider
18278
RxNav
2462496
ChEBI
135400
ChEMBL
CHEMBL2105961

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.0601 mg/mLALOGPS
logP3.82ALOGPS
logP3.95Chemaxon
logS-3.7ALOGPS
pKa (Strongest Basic)8.65Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count3Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area9.72 Å2Chemaxon
Rotatable Bond Count5Chemaxon
Refractivity101.78 m3·mol-1Chemaxon
Polarizability37 Å3Chemaxon
Number of Rings3Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-004i-1309000000-98af2e8c91507d093b54
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-004i-0009000000-279388cc97b475008b67
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-005a-1597000000-fcc91ff6e5993c77e0d6
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-00c0-9123000000-2bb4c5e38840a4839eb1
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-0089-9040000000-f214f84cadf915bbad05
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-0002-0950000000-e2eed054caded86a5a20
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-169.17552
predicted
DeepCCS 1.0 (2019)
[M+H]+171.53352
predicted
DeepCCS 1.0 (2019)
[M+Na]+177.73485
predicted
DeepCCS 1.0 (2019)

Drug created at December 23, 2019 17:16 / Updated at February 21, 2021 18:55