The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug data with comprehensive drug target information.
The latest release of DrugBank (version 5.1.2, released 2018-12-20) contains 11,928 drug entries including 2,541 approved small molecule drugs, 1,194 approved biotech (protein/peptide) drugs, 130 nutraceuticals and over 5,766 experimental drugs. Additionally, 5,134 non-redundant protein (i.e. drug target/enzyme/transporter/carrier) sequences are linked to these drug entries. Each DrugCard entry contains more than 200 data fields with half of the information being devoted to drug/chemical data and the other half devoted to drug target or protein data.
- BenzonatateFor the symptomatic relief of cough. Has also been applied locally in the oral cavity in adults by releasing the drug from the liquid-filled capsules to provide oropharyngeal anesthesia for...
- SalbutamolFor symptomatic relief and prevention of bronchospasm due to bronchial asthma, chronic bronchitis, and other chronic bronchopulmonary disorders such as COPD.
- OxycodoneFor the treatment of diarrhoea, pulmonary oedema and for the relief of moderate to moderately severe pain.
- CodeineFor treatment and management of pain (systemic). It is also used as an antidiarrheal and as a cough suppressant.
- MorphineFor the relief and treatment of severe pain.
Ketamine is an NMDA receptor antagonist with a potent anesthetic effect.It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor hallucinogenic effects and shorter psychotomimetic effects. It was FDA approved in 1970, and from there, it has been used as an anesthetic for children or patients undergoing minor surgeries but mainly for veterinary purposes.
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DrugBank is offered to the public as a freely available resource.
Use and re-distribution of the data, in whole or in part, for commercial purposes (including internal use) requires a license. We ask that users who download significant portions of the database cite the DrugBank paper in any resulting publications.