Cyclin-dependent kinase 2

Details

Name
Cyclin-dependent kinase 2
Kind
protein
Organism
Human
Polypeptides
NameUniProt ID
Cyclin-dependent kinase 2P24941Details

Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB018884-[5-(Trans-4-Aminocyclohexylamino)-3-Isopropylpyrazolo[1,5-a]Pyrimidin-7-Ylamino]-N,N-DimethylbenzenesulfonamideexperimentalunknownDetails
DB02010StaurosporineexperimentalunknownDetails
DB020914-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-YlamineexperimentalunknownDetails
DB02116OlomoucineexperimentalunknowninhibitorDetails
DB021974-[(4-Imidazo[1,2-a]Pyridin-3-Ylpyrimidin-2-Yl)Amino]BenzenesulfonamideexperimentalunknownDetails
DB022972-Amino-6-ChloropyrazineexperimentalunknownDetails
DB024076-O-Cyclohexylmethyl GuanineexperimentalunknownDetails
DB02538N-[4-(2-Methylimidazo[1,2-a]Pyridin-3-Yl)-2-Pyrimidinyl]AcetamideexperimentalunknownDetails
DB026031-Amino-6-Cyclohex-3-EnylmethyloxypurineexperimentalunknownDetails
DB02647N-(5-Cyclopropyl-1h-Pyrazol-3-Yl)BenzamideexperimentalunknownDetails
DB02733PurvalanolexperimentalunknownDetails
DB02833[4-(2-Amino-4-Methyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(3-Nitro-Phenyl)-AmineexperimentalunknownDetails
DB028985-{[(2-Amino-9h-Purin-6-Yl)Oxy]Methyl}-2-PyrrolidinoneexperimentalunknownDetails
DB029154-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(4-Trifluoromethyl-Phenyl)-AmineexperimentalunknownDetails
DB02950HymenialdisineexperimentalunknowninhibitorDetails
DB02963(5-Chloropyrazolo[1,5-a]Pyrimidin-7-Yl)-(4-Methanesulfonylphenyl)AmineexperimentalunknownDetails
DB029734-(5-Bromo-2-Oxo-2h-Indol-3-Ylazo)-BenzenesulfonamideexperimentalunknownDetails
DB030194-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-YlamineexperimentalunknownDetails
DB033074-[(6-Amino-4-Pyrimidinyl)Amino]BenzenesulfonamideexperimentalunknownDetails
DB033654-[3-Hydroxyanilino]-6,7-DimethoxyquinazolineexperimentalunknownDetails
DB03428SU9516experimentalunknowninhibitorDetails
DB034903-Pyridin-4-Yl-2,4-Dihydro-Indeno[1,2-.C.]PyrazoleexperimentalunknownDetails
DB03583(2e,3s)-3-Hydroxy-5'-[(4-Hydroxypiperidin-1-Yl)Sulfonyl]-3-Methyl-1,3-Dihydro-2,3'-Biindol-2'(1'h)-OneexperimentalunknownDetails
DB036631-[(2-Amino-6,9-Dihydro-1h-Purin-6-Yl)Oxy]-3-Methyl-2-ButanolexperimentalunknownDetails
DB037374-((3r,4s,5r)-4-Amino-3,5-Dihydroxy-Hex-1-Ynyl)-5-Fluoro-3-[1-(3-Methoxy-1h-Pyrrol-2-Yl)-Meth-(Z)-Ylidene]-1,3-Dihydro-Indol-2-OneexperimentalunknownDetails
DB03801Lysine Nz-Carboxylic AcidexperimentalunknownDetails
DB04006[2-Amino-6-(2,6-Difluoro-Benzoyl)-Imidazo[1,2-a]Pyridin-3-Yl]-Phenyl-MethanoneexperimentalunknownDetails
DB04101N-[4-(2,4-Dimethyl-1,3-Thiazol-5-Yl)Pyrimidin-2-Yl]-N'-HydroxyimidoformamideexperimentalunknownDetails
DB04186N'-(Pyrrolidino[2,1-B]Isoindolin-4-On-8-Yl)-N-(Pyridin-2-Yl)UreaexperimentalunknownDetails
DB042882-[Trans-(4-Aminocyclohexyl)Amino]-6-(Benzyl-Amino)-9-CyclopentylpurineexperimentalunknownDetails
DB044074-[4-(4-Methyl-2-Methylamino-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-PhenolexperimentalunknownDetails
DB045183-[4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-PhenolexperimentalunknownDetails
DB05037AT7519investigationalunknownDetails
DB04607PHENYLAMINOIMIDAZO(1,2-ALPHA)PYRIDINEexperimentalunknownDetails
DB04662OLOMOUCINE IIexperimentalunknownDetails
DB04669TRIAZOLOPYRIMIDINEexperimentalunknownDetails
DB03496Alvocidibexperimental, investigationalunknowninhibitorDetails
DB068444-[(7-OXO-7H-THIAZOLO[5,4-E]INDOL-8-YLMETHYL)-AMINO]-N-PYRIDIN-2-YL-BENZENESULFONAMIDEexperimentalunknownDetails
DB06888(13R,15S)-13-METHYL-16-OXA-8,9,12,22,24-PENTAAZAHEXACYCLO[15.6.2.16,9.1,12,15.0,2,7.0,21,25]HEPTACOSA-1(24),2,4,6,17(25),18,20-HEPTAENE-23,26-DIONEexperimentalunknownDetails
DB06944N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamideexperimentalunknownDetails
DB069482-ANILINO-6-CYCLOHEXYLMETHOXYPURINEexperimentalunknownDetails
DB069761-(5-OXO-2,3,5,9B-TETRAHYDRO-1H-PYRROLO[2,1-A]ISOINDOL-9-YL)-3-(5-PYRROLIDIN-2-YL-1H-PYRAZOL-3-YL)-UREAexperimentalunknownDetails
DB06983(5-phenyl-7-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-3-yl)methanolexperimentalunknownDetails
DB070242-(3,4-DIHYDROXYPHENYL)-8-(1,1-DIOXIDOISOTHIAZOLIDIN-2-YL)-3-HYDROXY-6-METHYL-4H-CHROMEN-4-ONEexperimentalunknownDetails
DB07054(2R)-1-(DIMETHYLAMINO)-3-{4-[(6-{[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-4-YL)AMINO]PHENOXY}PROPAN-2-OLexperimentalunknownDetails
DB070655-(2,3-dichlorophenyl)-N-(pyridin-4-ylmethyl)-3-thiocyanatopyrazolo[1,5-a]pyrimidin-7-amineexperimentalunknownDetails
DB07126O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINEexperimentalunknownDetails
DB07137(2S)-N-[(3Z)-5-CYCLOPROPYL-3H-PYRAZOL-3-YLIDENE]-2-[4-(2-OXOIMIDAZOLIDIN-1-YL)PHENYL]PROPANAMIDEexperimentalunknownDetails
DB071635-[(2-AMINOETHYL)AMINO]-6-FLUORO-3-(1H-PYRROL-2-YL)BENZO[CD]INDOL-2(1H)-ONEexperimentalunknownDetails
DB07164N-cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amineexperimentalunknownDetails
DB071793-((3-bromo-5-o-tolylpyrazolo[1,5-a]pyrimidin-7-ylamino)methyl)pyridine 1-oxideexperimentalunknownDetails
DB072036-CYCLOHEXYLMETHOXY-2-(3'-CHLOROANILINO) PURINEexperimentalunknownDetails
DB072103-bromo-5-phenyl-N-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amineexperimentalunknownDetails
DB07220N-[5-(1,1-DIOXIDOISOTHIAZOLIDIN-2-YL)-1H-INDAZOL-3-YL]-2-(4-PIPERIDIN-1-YLPHENYL)ACETAMIDEexperimentalunknownDetails
DB07431(3R)-3-(aminomethyl)-9-methoxy-1,2,3,4-tetrahydro-5H-[1]benzothieno[3,2-e][1,4]diazepin-5-oneexperimentalunknownDetails
DB074715-[5,6-BIS(METHYLOXY)-1H-BENZIMIDAZOL-1-YL]-3-{[1-(2-CHLOROPHENYL)ETHYL]OXY}-2-THIOPHENECARBOXAMIDEexperimentalunknownDetails
DB07493(2Z)-5'-BROMO-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE AMMONIATEexperimentalunknownDetails
DB07501(2S)-1-{4-[(4-anilino-5-bromopyrimidin-2-yl)amino]phenoxy}-3-(dimethylamino)propan-2-olexperimentalunknownDetails
DB07504(2R)-1-{4-[(4-anilino-5-bromopyrimidin-2-yl)amino]phenoxy}-3-(dimethylamino)propan-2-olexperimentalunknownDetails
DB075292-IMINO-5-(1-PYRIDIN-2-YL-METH-(E)-YLIDENE)-1,3-THIAZOLIDIN-4-ONEexperimentalunknownDetails
DB075314-{5-[(Z)-(2,4-DIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZENESULFONAMIDEexperimentalunknownDetails
DB075334-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-FURYL}-N-METHYLBENZENESULFONAMIDEexperimentalunknownDetails
DB075344-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZENESULFONAMIDEexperimentalunknownDetails
DB075384-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}-2-(TRIFLUOROMETHYL)BENZENESULFONAMIDEexperimentalunknownDetails
DB075394-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZOIC ACIDexperimentalunknownDetails
DB075404-{5-[(1Z)-1-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)ETHYL]-2-FURYL}BENZENESULFONAMIDEexperimentalunknownDetails
DB07562N-[4-(2,4-DIMETHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-N',N'-DIMETHYL-BENZENE-1,4-DIAMINEexperimentalunknownDetails
DB07595(5Z)-5-(3-BROMOCYCLOHEXA-2,5-DIEN-1-YLIDENE)-N-(PYRIDIN-4-YLMETHYL)-1,5-DIHYDROPYRAZOLO[1,5-A]PYRIMIDIN-7-AMINEexperimentalunknownDetails
DB076066-(3,4-DIHYDROXYBENZYL)-3-ETHYL-1-(2,4,6-TRICHLOROPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4(5H)-ONEexperimentalunknownDetails
DB076126-(3-AMINOPHENYL)-N-(TERT-BUTYL)-2-(TRIFLUOROMETHYL)QUINAZOLIN-4-AMINEexperimentalunknownDetails
DB076182-(4-(AMINOMETHYL)PIPERIDIN-1-YL)-N-(3_CYCLOHEXYL-4-OXO-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-5-YL)ACETAMIDEexperimentalunknownDetails
DB076221-(3-(2,4-DIMETHYLTHIAZOL-5-YL)-4-OXO-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-5-YL)-3-(4-METHYLPIPERAZIN-1-YL)UREAexperimentalunknownDetails
DB076854-{[5-(CYCLOHEXYLMETHOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDEexperimentalunknownDetails
DB076864-{[5-(CYCLOHEXYLAMINO)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDEexperimentalunknownDetails
DB076874-({5-[(4-AMINOCYCLOHEXYL)AMINO][1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL}AMINO)BENZENESULFONAMIDEexperimentalunknownDetails
DB076884-{[5-(CYCLOHEXYLOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDEexperimentalunknownDetails
DB077314-[(E)-(3,5-DIAMINO-1H-PYRAZOL-4-YL)DIAZENYL]PHENOLexperimentalunknownDetails
DB07750(2R)-1-[4-({4-[(2,5-dichlorophenyl)amino]pyrimidin-2-yl}amino)phenoxy]-3-(dimethylamino)propan-2-olexperimentalunknownDetails
DB07751(2S)-1-[4-({6-[(2,6-difluorophenyl)amino]pyrimidin-4-yl}amino)phenoxy]-3-(dimethylamino)propan-2-olexperimentalunknownDetails
DB07755(2S)-1-[4-({4-[(2,5-dichlorophenyl)amino]pyrimidin-2-yl}amino)phenoxy]-3-(dimethylamino)propan-2-olexperimentalunknownDetails
DB07761(2R)-1-[4-({6-[(2,6-difluorophenyl)amino]pyrimidin-4-yl}amino)phenoxy]-3-(dimethylamino)propan-2-olexperimentalunknownDetails
DB07790N-(2-METHOXYETHYL)-4-({4-[2-METHYL-1-(1-METHYLETHYL)-1H-IMIDAZOL-5-YL]PYRIMIDIN-2-YL}AMINO)BENZENESULFONAMIDEexperimentalunknownDetails
DB077914-{[4-(1-CYCLOPROPYL-2-METHYL-1H-IMIDAZOL-5-YL)PYRIMIDIN-2-YL]AMINO}-N-METHYLBENZENESULFONAMIDEexperimentalunknownDetails
DB078521-(3,5-DICHLOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXYLIC ACIDexperimentalunknownDetails
DB078891-(DIMETHYLAMINO)-3-(4-{{4-(2-METHYLIMIDAZO[1,2-A]PYRIDIN-3-YL)PYRIMIDIN-2-YL]AMINO}PHENOXY)PROPAN-2-OLexperimentalunknownDetails
DB07936N-(4-{[(3S)-3-(dimethylamino)pyrrolidin-1-yl]carbonyl}phenyl)-5-fluoro-4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]pyrimidin-2-amineexperimentalunknownDetails
DB079822-{4-[4-({4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]pyrimidin-2-yl}amino)phenyl]piperazin-1-yl}-2-oxoethanolexperimentalunknownDetails
DB02052Indirubin-3'-MonoximeexperimentalunknowninhibitorDetails
DB08066N-[3-(1H-BENZIMIDAZOL-2-YL)-1H-PYRAZOL-4-YL]BENZAMIDEexperimentalunknownDetails
DB08094(4-AMINO-2-{[1-(METHYLSULFONYL)PIPERIDIN-4-YL]AMINO}PYRIMIDIN-5-YL)(2,3-DIFLUORO-6-METHOXYPHENYL)METHANONEexperimentalunknownDetails
DB08122N-METHYL-4-{[(2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]AMINO}BENZENESULFONAMIDEexperimentalunknownDetails
DB08123N-METHYL-{4-[2-(7-OXO-6,7-DIHYDRO-8H-[1,3]THIAZOLO[5,4-E]INDOL-8-YLIDENE)HYDRAZINO]PHENYL}METHANESULFONAMIDEexperimentalunknownDetails
DB081243-{[(2,2-DIOXIDO-1,3-DIHYDRO-2-BENZOTHIEN-5-YL)AMINO]METHYLENE}-5-(1,3-OXAZOL-5-YL)-1,3-DIHYDRO-2H-INDOL-2-ONEexperimentalunknownDetails
DB081254-{[(2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]AMINO}-N-(1,3-THIAZOL-2-YL)BENZENESULFONAMIDEexperimentalunknownDetails
DB081263-{[4-([AMINO(IMINO)METHYL]AMINOSULFONYL)ANILINO]METHYLENE}-2-OXO-2,3-DIHYDRO-1H-INDOLEexperimentalunknownDetails
DB081325-hydroxynaphthalene-1-sulfonamideexperimentalunknownDetails
DB08133N-(4-sulfamoylphenyl)-1H-indazole-3-carboxamideexperimentalunknownDetails
DB081344-[(6-chloropyrazin-2-yl)amino]benzenesulfonamideexperimentalunknownDetails
DB08135N-phenyl-1H-pyrazole-3-carboxamideexperimentalunknownDetails
DB081364-(acetylamino)-N-(4-fluorophenyl)-1H-pyrazole-3-carboxamideexperimentalunknownDetails
DB08137(4E)-N-(4-fluorophenyl)-4-[(phenylcarbonyl)imino]-4H-pyrazole-3-carboxamideexperimentalunknownDetails
DB08138{[(2,6-difluorophenyl)carbonyl]amino}-N-(4-fluorophenyl)-1H-pyrazole-3-carboxamideexperimentalunknownDetails
DB081395-chloro-7-[(1-methylethyl)amino]pyrazolo[1,5-a]pyrimidine-3-carbonitrileexperimentalunknownDetails
DB081405-[(4-AMINOCYCLOHEXYL)AMINO]-7-(PROPAN-2-YLAMINO)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBONITRILEexperimentalunknownDetails
DB081414-{[(2,6-difluorophenyl)carbonyl]amino}-N-[(3S)-piperidin-3-yl]-1H-pyrazole-3-carboxamideexperimentalunknownDetails
DB081424-{[(2,6-dichlorophenyl)carbonyl]amino}-N-piperidin-4-yl-1H-pyrazole-3-carboxamideexperimentalunknownDetails
DB081784-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amineexperimentalunknownDetails
DB081824-(4-propoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amineexperimentalunknownDetails
DB08218HYDROXY(OXO)(3-{[(2Z)-4-[3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]PYRIMIDIN-2(5H)-YLIDENE]AMINO}PHENYL)AMMONIUMexperimentalunknownDetails
DB082194-METHYL-5-{(2E)-2-[(4-MORPHOLIN-4-YLPHENYL)IMINO]-2,5-DIHYDROPYRIMIDIN-4-YL}-1,3-THIAZOL-2-AMINEexperimentalunknownDetails
DB082336-CYCLOHEXYLMETHYLOXY-2-(4'-HYDROXYANILINO)PURINEexperimentalunknownDetails
DB082414-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)--BENZAMIDEexperimentalunknownDetails
DB082476-(CYCLOHEXYLMETHOXY)-8-ISOPROPYL-9H-PURIN-2-AMINEexperimentalunknownDetails
DB082483-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)-BENZENESULFONAMIDEexperimentalunknownDetails
DB08285(2R)-2-{[4-(benzylamino)-8-(1-methylethyl)pyrazolo[1,5-a][1,3,5]triazin-2-yl]amino}butan-1-olexperimentalunknownDetails
DB083093-({2-[(4-{[6-(CYCLOHEXYLMETHOXY)-9H-PURIN-2-YL]AMINO}PHENYL)SULFONYL]ETHYL}AMINO)PROPAN-1-OLexperimentalunknownDetails
DB083126-CYCLOHEXYLMETHYLOXY-5-NITROSO-PYRIMIDINE-2,4-DIAMINEexperimentalunknownDetails
DB083551-methyl-8-(phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylic acidexperimentalunknownDetails
DB084416-BROMO-13-THIA-2,4,8,12,19-PENTAAZATRICYCLO[12.3.1.1~3,7~]NONADECA-1(18),3(19),4,6,14,16-HEXAENE 13,13-DIOXIDEexperimentalunknownDetails
DB08463(2R)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9H-purin-2-yl}amino)butan-1-olexperimentalunknownDetails
DB085271-[4-(AMINOSULFONYL)PHENYL]-1,6-DIHYDROPYRAZOLO[3,4-E]INDAZOLE-3-CARBOXAMIDEexperimentalunknownDetails
DB085315-(2,3-dichlorophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amineexperimentalunknownDetails
DB085326-(2-fluorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amineexperimentalunknownDetails
DB085333-methyl-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amineexperimentalunknownDetails
DB085345-(2-fluorophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amineexperimentalunknownDetails
DB085353-bromo-5-phenyl-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amineexperimentalunknownDetails
DB085363-bromo-5-phenyl-N-(pyrimidin-5-ylmethyl)pyrazolo[1,5-a]pyridin-7-amineexperimentalunknownDetails
DB085373-bromo-6-phenyl-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amineexperimentalunknownDetails
DB08538N-((2-aminopyrimidin-5-yl)methyl)-5-(2,6-difluorophenyl)-3-ethylpyrazolo[1,5-a]pyrimidin-7-amineexperimentalunknownDetails
DB085393-cyclopropyl-5-phenyl-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amineexperimentalunknownDetails
DB085724-{[4-AMINO-6-(CYCLOHEXYLMETHOXY)-5-NITROSOPYRIMIDIN-2-YL]AMINO}BENZAMIDEexperimentalunknownDetails
DB086734-[(5-ISOPROPYL-1,3-THIAZOL-2-YL)AMINO]BENZENESULFONAMIDEexperimentalunknownDetails
DB08677N-(5-ISOPROPYL-THIAZOL-2-YL)-2-PYRIDIN-3-YL-ACETAMIDEexperimentalunknownDetails
DB086949-amino-5-(2-aminopyrimidin-4-yl)pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidin-4-olexperimentalunknownDetails
DB08768N-(3-METHYLBUT-2-EN-1-YL)-9H-PURIN-6-AMINEexperimentalunknownDetails
DB06616BosutinibapprovedunknowninhibitorDetails