Cytochrome P450 2C8

Details

Name
Cytochrome P450 2C8
Kind
protein
Organism
Human
Polypeptides
NameUniProt ID
Cytochrome P450 2C8P10632Details

Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB03796Palmitic Acidapproved, experimentalunknownDetails
DB00214TorasemideapprovedunknownsubstrateDetails
DB00252Phenytoinapproved, vet_approvedunknownsubstrateinducerDetails
DB00412Rosiglitazoneapproved, investigationalunknownsubstrateinhibitorDetails
DB00439CerivastatinwithdrawnunknownsubstrateinhibitorDetails
DB00564Carbamazepineapproved, investigationalunknownsubstrateinducerDetails
DB00682WarfarinapprovedunknownsubstrateinhibitorDetails
DB00755Tretinoinapproved, investigational, nutraceuticalunknownsubstrateDetails
DB00912Repaglinideapproved, investigationalunknownsubstrateDetails
DB01118Amiodaroneapproved, investigationalunknownsubstrateDetails
DB01132Pioglitazoneapproved, investigationalunknownsubstrateinhibitorDetails
DB01198ZopicloneapprovedunknownsubstrateDetails
DB01229Paclitaxelapproved, vet_approvedunknownsubstrateDetails
DB01261Sitagliptinapproved, investigationalunknownsubstrateDetails
DB01259Lapatinibapproved, investigationalunknownsubstrateinhibitorDetails
DB01320FosphenytoinapprovedunknownsubstrateinducerDetails
DB00227Lovastatinapproved, investigationalunknowninhibitorDetails
DB00440Trimethoprimapproved, vet_approvedunknownsubstrateinhibitorDetails
DB00471MontelukastapprovedunknowninhibitorDetails
DB00549Zafirlukastapproved, investigationalunknownsubstrateinhibitorDetails
DB00586Diclofenacapproved, vet_approvedunknownsubstrateDetails
DB00613Amodiaquineapproved, investigationalunknownsubstrateDetails
DB00622NicardipineapprovedunknownsubstrateinhibitorDetails
DB00641SimvastatinapprovedunknownsubstrateinhibitorDetails
DB01026Ketoconazoleapproved, investigationalunknowninhibitorDetails
DB01045RifampicinapprovedunknownsubstrateinhibitorinducerDetails
DB01124TolbutamideapprovedunknownsubstrateinhibitorDetails
DB01241GemfibrozilapprovedunknowninhibitorinducerDetails
DB01424Aminophenazoneapproved, withdrawnunknownsubstrateDetails
DB01095FluvastatinapprovedunknownsubstrateinhibitorDetails
DB01023Felodipineapproved, investigationalunknowninhibitorDetails
DB00197Troglitazoneinvestigational, withdrawnunknownsubstrateinhibitorDetails
DB00796Candesartan cilexetilapprovedunknowninhibitorDetails
DB00257Clotrimazoleapproved, vet_approvedunknowninhibitorDetails
DB00764Mometasoneapproved, vet_approvedunknowninhibitorDetails
DB00938SalmeterolapprovedunknowninhibitorDetails
DB00481Raloxifeneapproved, investigationalunknowninhibitorDetails
DB01039FenofibrateapprovedunknowninhibitorDetails
DB00503Ritonavirapproved, investigationalunknowninhibitorinducerDetails
DB00451LevothyroxineapprovedunknowninhibitorDetails
DB00675TamoxifenapprovedunknowninhibitorDetails
DB00455LoratadineapprovedunknownsubstrateinhibitorDetails
DB04216Quercetinexperimental, investigationalunknowninhibitorDetails
DB01062Oxybutyninapproved, investigationalunknowninhibitorDetails
DB00603Medroxyprogesterone acetateapproved, investigationalunknowninhibitorDetails
DB00977Ethinyl EstradiolapprovedunknowninhibitorDetails
DB00421SpironolactoneapprovedunknowninhibitorDetails
DB01029Irbesartanapproved, investigationalunknownsubstrateinhibitorDetails
DB01181IfosfamideapprovedunknownsubstrateinducerDetails
DB01115NifedipineapprovedunknowninhibitorDetails
DB00468QuinineapprovedunknownsubstrateinhibitorDetails
DB01435AntipyrineapprovedunknownsubstrateDetails
DB00250Dapsoneapproved, investigationalunknownsubstrateDetails
DB00946Phenprocoumonapproved, investigationalunknownsubstrateDetails
DB00857Terbinafineapproved, investigational, vet_approvedunknownsubstrateDetails
DB00972AzelastineapprovedunknownsubstrateDetails
DB00398Sorafenibapproved, investigationalunknownsubstrateinhibitorDetails
DB01174PhenobarbitalapprovedunknowninducerDetails
DB00794Primidoneapproved, vet_approvedunknowninducerDetails
DB01201RifapentineapprovedunknowninducerDetails
DB00418Secobarbitalapproved, vet_approvedunknowninducerDetails
DB06210EltrombopagapprovedunknownsubstrateinhibitorDetails
DB00678LosartanapprovedunknownsubstrateinhibitorDetails
DB04868Nilotinibapproved, investigationalunknowninhibitorDetails
DB00661VerapamilapprovedunknownsubstrateDetails
DB01050IbuprofenapprovedunknownsubstrateDetails
DB00788Naproxenapproved, vet_approvedunknownsubstrateDetails
DB00921Buprenorphineapproved, illicit, investigational, vet_approvedunknownsubstrateDetails
DB00333MethadoneapprovedunknownsubstrateDetails
DB00201CaffeineapprovedunknownsubstrateDetails
DB04725LicofeloneinvestigationalunknownsubstrateinhibitorDetails
DB06739SeratrodastapprovedunknownsubstrateDetails
DB00402EszopicloneapprovedunknownsubstrateDetails
DB08607(5R)-5-(4-{[(2R)-6-HYDROXY-2,5,7,8-TETRAMETHYL-3,4-DIHYDRO-2H-CHROMEN-2-YL]METHOXY}BENZYL)-1,3-THIAZOLIDINE-2,4-DIONEexperimentalunknownDetails
DB06772CabazitaxelapprovedunknownsubstrateDetails
DB01583LiotrixapprovedunknowninhibitorDetails
DB00945Acetylsalicylic acidapproved, vet_approvedunknownsubstrateDetails
DB00321AmitriptylineapprovedunknownsubstrateinhibitorDetails
DB00381AmlodipineapprovedunknowninhibitorDetails
DB00701AmprenavirapprovedunknownsubstrateDetails
DB01076AtorvastatinapprovedunknownsubstrateinhibitorDetails
DB01393BezafibrateapprovedunknowninhibitorDetails
DB00835BrompheniramineapprovedunknownsubstrateDetails
DB01156BupropionapprovedunknownsubstrateDetails
DB00748CarbinoxamineapprovedunknownsubstrateDetails
DB00446Chloramphenicolapproved, vet_approvedunknowninhibitorDetails
DB00608Chloroquineapproved, vet_approvedunknownsubstrateDetails
DB00091Cyclosporineapproved, investigational, vet_approvedunknowninhibitorDetails
DB00501CimetidineapprovedunknowninhibitorDetails
DB00604Cisaprideapproved, investigational, withdrawnunknownsubstrateDetails
DB00758Clopidogrelapproved, nutraceuticalunknowninhibitorDetails
DB00363ClozapineapprovedunknownsubstrateDetails
DB00907Cocaineapproved, illicitunknowninhibitorDetails
DB01394ColchicineapprovedunknowninhibitorinducerDetails
DB00169Cholecalciferolapproved, nutraceuticalunknowninhibitorDetails
DB00531Cyclophosphamideapproved, investigationalunknownsubstrateinducerDetails
DB00705DelavirdineapprovedunknowninhibitorDetails
DB01234Dexamethasoneapproved, investigational, vet_approvedunknowninducerDetails
DB00514DextromethorphanapprovedunknownsubstrateDetails
DB00647Dextropropoxypheneapproved, illicit, investigational, withdrawnunknowninhibitorDetails
DB00829Diazepamapproved, illicit, vet_approvedunknownsubstrateDetails
DB00343DiltiazemapprovedunknownsubstrateDetails
DB01184Domperidoneapproved, investigational, vet_approvedunknownsubstrateDetails
DB00783Estradiolapproved, investigational, vet_approvedunknownsubstrateDetails
DB00773EtoposideapprovedunknowninhibitorDetails
DB00544FluorouracilapprovedunknownsubstrateDetails
DB01218HalofantrineapprovedunknownsubstrateDetails
DB00741Hydrocortisoneapproved, vet_approvedunknowninducerDetails
DB00951IsoniazidapprovedunknowninhibitorDetails
DB01221Ketamineapproved, vet_approvedunknownsubstrateDetails
DB06738Ketobemidoneapproved, investigationalunknownsubstrateDetails
DB01009Ketoprofenapproved, vet_approvedunknowninhibitorDetails
DB00448Lansoprazoleapproved, investigationalunknownsubstrateinhibitorDetails
DB00281Lidocaineapproved, vet_approvedunknownsubstrateDetails
DB00784Mefenamic acidapprovedunknownsubstrateinhibitorDetails
DB00814Meloxicamapproved, vet_approvedunknownsubstrateinhibitorDetails
DB00532Mephenytoininvestigational, withdrawnunknownsubstrateDetails
DB00916MetronidazoleapprovedunknowninhibitorDetails
DB00370MirtazapineapprovedunknownsubstrateDetails
DB00295Morphineapproved, investigationalunknownsubstrateDetails
DB01183Naloxoneapproved, vet_approvedunknownsubstrateDetails
DB00184NicotineapprovedunknownsubstrateDetails
DB00665NilutamideapprovedunknowninhibitorDetails
DB06712Nilvadipineapproved, investigationalunknowninhibitorDetails
DB00338Omeprazoleapproved, investigational, vet_approvedunknownsubstrateDetails
DB00316AcetaminophenapprovedunknownsubstrateDetails
DB00715Paroxetineapproved, investigationalunknowninhibitorDetails
DB00738PentamidineapprovedunknownsubstrateDetails
DB00850PerphenazineapprovedunknownsubstrateDetails
DB00780PhenelzineapprovedunknowninhibitorDetails
DB00554Piroxicamapproved, investigationalunknownsubstrateinhibitorDetails
DB00175PravastatinapprovedunknowninhibitorDetails
DB01032ProbenecidapprovedunknowninducerDetails
DB00396Progesteroneapproved, vet_approvedunknownsubstrateDetails
DB01182PropafenoneapprovedunknowninhibitorDetails
DB00818Propofolapproved, investigational, vet_approvedunknownsubstrateDetails
DB00205Pyrimethamineapproved, vet_approvedunknowninhibitorDetails
DB00908QuinidineapprovedunknownsubstrateDetails
DB00533Rofecoxibinvestigational, withdrawnunknownsubstrateDetails
DB01698Rutinexperimental, investigationalunknowninhibitorDetails
DB01232Saquinavirapproved, investigationalunknowninhibitorDetails
DB01037Selegilineapproved, investigational, vet_approvedunknownsubstrateDetails
DB00359Sulfadiazineapproved, vet_approvedunknownsubstrateDetails
DB01015SulfamethoxazoleapprovedunknowninhibitorDetails
DB06729SulfaphenazoleapprovedunknowninhibitorDetails
DB01138SulfinpyrazoneapprovedunknownsubstrateDetails
DB00799Tazaroteneapproved, investigationalunknownsubstrateDetails
DB01079Tegaserodinvestigational, withdrawnunknowninhibitorDetails
DB00231TemazepamapprovedunknownsubstrateDetails
DB00342TerfenadinewithdrawnunknowninhibitorDetails
DB00624Testosteroneapproved, investigationalunknownsubstrateDetails
DB00277TheophyllineapprovedunknownsubstrateDetails
DB00679Thioridazineapproved, withdrawnunknowninhibitorDetails
DB00208TiclopidineapprovedunknowninhibitorDetails
DB01007TioconazoleapprovedunknowninhibitorDetails
DB00897TriazolamapprovedunknowninhibitorDetails
DB00347TrimethadioneapprovedunknownsubstrateDetails
DB13179TroleandomycinapprovedunknowninhibitorDetails
DB00313Valproic Acidapproved, investigationalunknowninhibitorDetails
DB00495ZidovudineapprovedunknownsubstrateDetails
DB00530Erlotinibapproved, investigationalunknownsubstrateinhibitorDetails
DB00617ParamethadioneapprovedunknownsubstrateDetails
DB06589PazopanibapprovedunknownsubstrateDetails
DB00255Diethylstilbestrolapproved, investigationalunknowninhibitorDetails
DB00836LoperamideapprovedunknownsubstrateDetails
DB00918Almotriptanapproved, investigationalunknownsubstrateDetails
DB05229BeraprostinvestigationalunknownsubstrateDetails
DB06770Benzyl alcoholapprovedunknownsubstrateDetails
DB08860PitavastatinapprovedunknownsubstrateDetails
DB05812AbirateroneapprovedunknowninhibitorDetails
DB06605ApixabanapprovedunknownsubstrateDetails
DB08828VismodegibapprovedunknowninhibitorDetails
DB08896RegorafenibapprovedunknowninhibitorDetails
DB08899EnzalutamideapprovedunknownsubstrateinhibitorDetails
DB08901PonatinibapprovedunknownsubstrateinhibitorDetails
DB08911TrametinibapprovedunknowninhibitorDetails
DB08912DabrafenibapprovedunknownsubstrateDetails
DB00688Mycophenolate mofetilapproved, investigationalunknownsubstrateDetails
DB08918LevomilnacipranapprovedunknownsubstrateDetails
DB00951IsoniazidapprovedunknownDetails
DB09080OlodaterolapprovednosubstrateDetails
DB09054IdelalisibapprovednoinhibitorDetails
DB09068VortioxetineapprovednosubstrateDetails
DB09280LumacaftorapprovednoinhibitorinducerDetails
DB09570IxazomibapprovedunknownsubstrateDetails
DB11362SelexipagapprovednosubstrateDetails
DB08931RiociguatapprovedunknownsubstrateDetails
DB09183DasabuvirapprovednosubstrateDetails
DB09296OmbitasvirapprovednosubstrateDetails
DB01601LopinavirapprovedunknowninhibitorDetails
DB00482Celecoxibapproved, investigationalunknowninhibitorDetails
DB00625Efavirenzapproved, investigationalunknowninhibitorDetails
DB01129Rabeprazoleapproved, investigationalunknowninhibitorDetails
DB08880TeriflunomideapprovedunknowninhibitorDetails
DB09396Propoxyphene napsylateapprovedunknowninhibitorDetails
DB05219CrisaboroleapprovednoinhibitorDetails
DB06595MidostaurinapprovedunknowninhibitorinducerDetails
DB05015Belinostatapproved, investigationalunknowninhibitorDetails
DB11613VelpatasvirapprovednosubstrateDetails
DB06670OdanacatibinvestigationalnosubstrateDetails
DB01685Topiroxostatapproved, investigationalunknowninhibitorDetails
DB08922PerospironeapprovedunknownsubstrateDetails
DB12026VoxilaprevirapprovednosubstrateDetails
DB13874EnasidenibapprovedunknownsubstrateinhibitorDetails
DB13919CandesartanexperimentalunknowninhibitorDetails
DB12070LetermovirapprovednoinhibitorDetails
DB12267BrigatinibapprovednosubstrateDetails