NameCytochrome P450 2C8
Kindprotein
OrganismHuman
Polypeptides
NameUniProt ID
Cytochrome P450 2C8P10632 Details

Drugs

DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB03796Palmitic AcidexperimentalunknownDetails
DB00214TorasemideapprovedunknownsubstrateDetails
DB00252Phenytoinapproved, vet_approvedunknownsubstrateinducerDetails
DB00412Rosiglitazoneapproved, investigationalunknownsubstrateinhibitorDetails
DB00439CerivastatinwithdrawnunknownsubstrateinhibitorDetails
DB00564Carbamazepineapproved, investigationalunknownsubstrateinducerDetails
DB00682WarfarinapprovedunknownsubstrateinhibitorDetails
DB00755Tretinoinapproved, investigational, nutraceuticalunknownsubstrateDetails
DB00912Repaglinideapproved, investigationalunknownsubstrateDetails
DB01118Amiodaroneapproved, investigationalunknownsubstrateDetails
DB01132Pioglitazoneapproved, investigationalunknownsubstrateinhibitorDetails
DB01198ZopicloneapprovedunknownsubstrateDetails
DB01229Paclitaxelapproved, vet_approvedunknownsubstrateDetails
DB01261Sitagliptinapproved, investigationalunknownsubstrateDetails
DB01259Lapatinibapproved, investigationalunknownsubstrateinhibitorDetails
DB01320FosphenytoinapprovedunknownsubstrateinducerDetails
DB00227Lovastatinapproved, investigationalunknowninhibitorDetails
DB00440Trimethoprimapproved, vet_approvedunknownsubstrateinhibitorDetails
DB00471MontelukastapprovedunknowninhibitorDetails
DB00549Zafirlukastapproved, investigationalunknownsubstrateinhibitorDetails
DB00586Diclofenacapproved, vet_approvedunknownsubstrateDetails
DB00613AmodiaquineapprovedunknownsubstrateDetails
DB00622NicardipineapprovedunknownsubstrateinhibitorDetails
DB00641SimvastatinapprovedunknownsubstrateinhibitorDetails
DB01026Ketoconazoleapproved, investigationalunknowninhibitorDetails
DB01045RifampicinapprovedunknownsubstrateinhibitorinducerDetails
DB01124TolbutamideapprovedunknownsubstrateinhibitorDetails
DB01241GemfibrozilapprovedunknowninhibitorinducerDetails
DB01424Aminophenazoneapproved, withdrawnunknownsubstrateDetails
DB01095FluvastatinapprovedunknownsubstrateinhibitorDetails
DB01023Felodipineapproved, investigationalunknowninhibitorDetails
DB00197TroglitazonewithdrawnunknownsubstrateinhibitorDetails
DB00796CandesartanapprovedunknowninhibitorDetails
DB00257Clotrimazoleapproved, vet_approvedunknowninhibitorDetails
DB00764Mometasoneapproved, vet_approvedunknowninhibitorDetails
DB00938SalmeterolapprovedunknowninhibitorDetails
DB00481Raloxifeneapproved, investigationalunknowninhibitorDetails
DB01039FenofibrateapprovedunknowninhibitorDetails
DB00503Ritonavirapproved, investigationalunknowninhibitorinducerDetails
DB00451LevothyroxineapprovedunknowninhibitorDetails
DB00675TamoxifenapprovedunknowninhibitorDetails
DB00455LoratadineapprovedunknownsubstrateinhibitorDetails
DB04216QuercetinexperimentalunknowninhibitorDetails
DB01062Oxybutyninapproved, investigationalunknowninhibitorDetails
DB00603Medroxyprogesterone acetateapproved, investigationalunknowninhibitorDetails
DB00977Ethinyl EstradiolapprovedunknowninhibitorDetails
DB00421SpironolactoneapprovedunknowninhibitorDetails
DB01029Irbesartanapproved, investigationalunknownsubstrateinhibitorDetails
DB01181IfosfamideapprovedunknownsubstrateinducerDetails
DB01115NifedipineapprovedunknowninhibitorDetails
DB00468QuinineapprovedunknownsubstrateinhibitorDetails
DB01435AntipyrineapprovedunknownsubstrateDetails
DB00250Dapsoneapproved, investigationalunknownsubstrateDetails
DB00946PhenprocoumonapprovedunknownsubstrateDetails
DB00857Terbinafineapproved, investigational, vet_approvedunknownsubstrateDetails
DB00972AzelastineapprovedunknownsubstrateDetails
DB00398Sorafenibapproved, investigationalunknownsubstrateinhibitorDetails
DB01174PhenobarbitalapprovedunknowninducerDetails
DB00794Primidoneapproved, vet_approvedunknowninducerDetails
DB01201RifapentineapprovedunknowninducerDetails
DB00418Secobarbitalapproved, vet_approvedunknowninducerDetails
DB06210EltrombopagapprovedunknownsubstrateinhibitorDetails
DB00678LosartanapprovedunknownsubstrateinhibitorDetails
DB04868Nilotinibapproved, investigationalunknowninhibitorDetails
DB00661VerapamilapprovedunknownsubstrateDetails
DB01050IbuprofenapprovedunknownsubstrateDetails
DB00788Naproxenapproved, vet_approvedunknownsubstrateDetails
DB00921Buprenorphineapproved, illicit, investigational, vet_approvedunknownsubstrateDetails
DB00333MethadoneapprovedunknownsubstrateDetails
DB00201CaffeineapprovedunknownsubstrateDetails
DB04725LicofeloneinvestigationalunknownsubstrateinhibitorDetails
DB06739SeratrodastapprovedunknownsubstrateDetails
DB00402EszopicloneapprovedunknownsubstrateDetails
DB08607(5R)-5-(4-{[(2R)-6-HYDROXY-2,5,7,8-TETRAMETHYL-3,4-DIHYDRO-2H-CHROMEN-2-YL]METHOXY}BENZYL)-1,3-THIAZOLIDINE-2,4-DIONEexperimentalunknownDetails
DB06772CabazitaxelapprovedunknownsubstrateDetails
DB01583LiotrixapprovedunknowninhibitorDetails
DB00945Acetylsalicylic acidapproved, vet_approvedunknownsubstrateDetails
DB00321AmitriptylineapprovedunknownsubstrateinhibitorDetails
DB00381AmlodipineapprovedunknowninhibitorDetails
DB00701AmprenavirapprovedunknownsubstrateDetails
DB01076AtorvastatinapprovedunknownsubstrateinhibitorDetails
DB01393BezafibrateapprovedunknowninhibitorDetails
DB00835BrompheniramineapprovedunknownsubstrateDetails
DB01156BupropionapprovedunknownsubstrateDetails
DB00748CarbinoxamineapprovedunknownsubstrateDetails
DB00446Chloramphenicolapproved, vet_approvedunknowninhibitorDetails
DB00608Chloroquineapproved, vet_approvedunknownsubstrateDetails
DB00091Cyclosporineapproved, investigational, vet_approvedunknowninhibitorDetails
DB00501CimetidineapprovedunknowninhibitorDetails
DB00604Cisaprideapproved, investigational, withdrawnunknownsubstrateDetails
DB00758Clopidogrelapproved, nutraceuticalunknowninhibitorDetails
DB00363ClozapineapprovedunknownsubstrateDetails
DB00907Cocaineapproved, illicitunknowninhibitorDetails
DB01394ColchicineapprovedunknowninhibitorinducerDetails
DB00169Cholecalciferolapproved, nutraceuticalunknowninhibitorDetails
DB00531Cyclophosphamideapproved, investigationalunknownsubstrateinducerDetails
DB00705DelavirdineapprovedunknowninhibitorDetails
DB01234Dexamethasoneapproved, investigational, vet_approvedunknowninducerDetails
DB00514DextromethorphanapprovedunknownsubstrateDetails
DB00647Dextropropoxypheneapproved, illicit, withdrawnunknowninhibitorDetails
DB00829Diazepamapproved, illicit, vet_approvedunknownsubstrateDetails
DB00343DiltiazemapprovedunknownsubstrateDetails
DB01184Domperidoneapproved, investigational, vet_approvedunknownsubstrateDetails
DB00783Estradiolapproved, investigational, vet_approvedunknownsubstrateDetails
DB00773EtoposideapprovedunknowninhibitorDetails
DB00544FluorouracilapprovedunknownsubstrateDetails
DB01218HalofantrineapprovedunknownsubstrateDetails
DB00741Hydrocortisoneapproved, vet_approvedunknowninducerDetails
DB00951IsoniazidapprovedunknowninhibitorDetails
DB01221Ketamineapproved, vet_approvedunknownsubstrateDetails
DB06738KetobemidoneapprovedunknownsubstrateDetails
DB01009Ketoprofenapproved, vet_approvedunknowninhibitorDetails
DB00448Lansoprazoleapproved, investigationalunknownsubstrateinhibitorDetails
DB00281Lidocaineapproved, vet_approvedunknownsubstrateDetails
DB00784Mefenamic acidapprovedunknownsubstrateinhibitorDetails
DB00814Meloxicamapproved, vet_approvedunknownsubstrateinhibitorDetails
DB00532Mephenytoininvestigational, withdrawnunknownsubstrateDetails
DB00916MetronidazoleapprovedunknowninhibitorDetails
DB00370MirtazapineapprovedunknownsubstrateDetails
DB00295Morphineapproved, investigationalunknownsubstrateDetails
DB01183Naloxoneapproved, vet_approvedunknownsubstrateDetails
DB00184NicotineapprovedunknownsubstrateDetails
DB00665NilutamideapprovedunknowninhibitorDetails
DB06712NilvadipineapprovedunknowninhibitorDetails
DB00338Omeprazoleapproved, investigational, vet_approvedunknownsubstrateDetails
DB00316AcetaminophenapprovedunknownsubstrateDetails
DB00715Paroxetineapproved, investigationalunknowninhibitorDetails
DB00738PentamidineapprovedunknownsubstrateDetails
DB00850PerphenazineapprovedunknownsubstrateDetails
DB00780PhenelzineapprovedunknowninhibitorDetails
DB00554Piroxicamapproved, investigationalunknownsubstrateinhibitorDetails
DB00175PravastatinapprovedunknowninhibitorDetails
DB01032ProbenecidapprovedunknowninducerDetails
DB00396Progesteroneapproved, vet_approvedunknownsubstrateDetails
DB01182PropafenoneapprovedunknowninhibitorDetails
DB00818Propofolapproved, investigational, vet_approvedunknownsubstrateDetails
DB00205Pyrimethamineapproved, vet_approvedunknowninhibitorDetails
DB00908QuinidineapprovedunknownsubstrateDetails
DB00533Rofecoxibinvestigational, withdrawnunknownsubstrateDetails
DB01698RutinexperimentalunknowninhibitorDetails
DB01232Saquinavirapproved, investigationalunknowninhibitorDetails
DB01037Selegilineapproved, investigational, vet_approvedunknownsubstrateDetails
DB00359Sulfadiazineapproved, vet_approvedunknownsubstrateDetails
DB01015SulfamethoxazoleapprovedunknowninhibitorDetails
DB06729SulfaphenazoleapprovedunknowninhibitorDetails
DB01138SulfinpyrazoneapprovedunknownsubstrateDetails
DB00799Tazaroteneapproved, investigationalunknownsubstrateDetails
DB01079Tegaserodinvestigational, withdrawnunknowninhibitorDetails
DB00231TemazepamapprovedunknownsubstrateDetails
DB00342TerfenadinewithdrawnunknowninhibitorDetails
DB00624Testosteroneapproved, investigationalunknownsubstrateDetails
DB00277TheophyllineapprovedunknownsubstrateDetails
DB00679ThioridazinewithdrawnunknowninhibitorDetails
DB00208TiclopidineapprovedunknowninhibitorDetails
DB01007TioconazoleapprovedunknowninhibitorDetails
DB00897TriazolamapprovedunknowninhibitorDetails
DB00347TrimethadioneapprovedunknownsubstrateDetails
DB13179TroleandomycinapprovedunknowninhibitorDetails
DB00313Valproic Acidapproved, investigationalunknowninhibitorDetails
DB00495ZidovudineapprovedunknownsubstrateDetails
DB00530Erlotinibapproved, investigationalunknownsubstrateinhibitorDetails
DB00617ParamethadioneapprovedunknownsubstrateDetails
DB06589PazopanibapprovedunknownsubstrateDetails
DB00255DiethylstilbestrolapprovedunknowninhibitorDetails
DB00836LoperamideapprovedunknownsubstrateDetails
DB00918Almotriptanapproved, investigationalunknownsubstrateDetails
DB05229BeraprostinvestigationalunknownsubstrateDetails
DB06770Benzyl alcoholapprovedunknownsubstrateDetails
DB08860PitavastatinapprovedunknownsubstrateDetails
DB05812AbirateroneapprovedunknowninhibitorDetails
DB06605ApixabanapprovedunknownsubstrateDetails
DB08828VismodegibapprovedunknowninhibitorDetails
DB08896RegorafenibapprovedunknowninhibitorDetails
DB08899EnzalutamideapprovedunknownsubstrateinhibitorDetails
DB08901PonatinibapprovedunknownsubstrateinhibitorDetails
DB08911TrametinibapprovedunknowninhibitorDetails
DB08912DabrafenibapprovedunknownsubstrateDetails
DB00688Mycophenolate mofetilapproved, investigationalunknownsubstrateDetails
DB08918LevomilnacipranapprovedunknownsubstrateDetails
DB00951IsoniazidapprovedunknownDetails
DB09080OlodaterolapprovednosubstrateDetails
DB09054IdelalisibapprovednoinhibitorDetails
DB09068VortioxetineapprovednosubstrateDetails
DB09280LumacaftorapprovednoinhibitorinducerDetails
DB09570IxazomibapprovedunknownsubstrateDetails
DB11362SelexipagapprovednosubstrateDetails
DB08931RiociguatapprovedunknownsubstrateDetails
DB09183DasabuvirapprovednosubstrateDetails
DB09296OmbitasvirapprovednosubstrateDetails
DB01601LopinavirapprovedunknowninhibitorDetails
DB00482Celecoxibapproved, investigationalunknowninhibitorDetails
DB00625Efavirenzapproved, investigationalunknowninhibitorDetails
DB01129Rabeprazoleapproved, investigationalunknowninhibitorDetails
DB08880TeriflunomideapprovedunknowninhibitorDetails
DB09396Propoxyphene napsylateapprovedunknowninhibitorDetails
DB05219CrisaboroleapprovednoinhibitorDetails
DB06595MidostaurinapprovedunknowninhibitorinducerDetails
DB05015Belinostatapproved, investigationalunknowninhibitorDetails
DB11613VelpatasvirapprovednosubstrateDetails
DB06670OdanacatibinvestigationalnosubstrateDetails
DB01685TopiroxostatapprovedunknowninhibitorDetails
DB08922PerospironeapprovedunknownsubstrateDetails
DB12026VoxilaprevirapprovednosubstrateDetails
DB13874EnasidenibapprovedunknownsubstrateinhibitorDetails