NameCytochrome P450 2C19
Kindprotein
OrganismHuman
Polypeptides
NameUniProt ID
Cytochrome P450 2C19P33261 Details

Drugs

DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB00188Bortezomibapproved, investigationalnosubstrateinhibitorDetails
DB00213PantoprazoleapprovedunknownsubstrateinhibitorDetails
DB00215CitalopramapprovedunknownsubstrateinhibitorDetails
DB00220NelfinavirapprovedunknownsubstrateinhibitorDetails
DB00231TemazepamapprovedunknownsubstrateDetails
DB00252Phenytoinapproved, vet_approvedunknownsubstrateinducerDetails
DB00273TopiramateapprovedunknowninhibitorDetails
DB00328Indomethacinapproved, investigationalunknownsubstrateinhibitorDetails
DB00338Omeprazoleapproved, investigational, vet_approvedunknownsubstrateinhibitorDetails
DB00349Clobazamapproved, illicitunknownsubstrateDetails
DB00395CarisoprodolapprovedunknownsubstrateDetails
DB00396Progesteroneapproved, vet_approvedunknownsubstrateinhibitorDetails
DB00420Promazineapproved, vet_approvedunknownsubstrateDetails
DB00444TeniposideapprovedunknownsubstrateDetails
DB00448Lansoprazoleapproved, investigationalunknownsubstrateinhibitorDetails
DB00546AdinazolamapprovedunknownsubstrateDetails
DB00582Voriconazoleapproved, investigationalunknownsubstrateinhibitorDetails
DB00665NilutamideapprovedunknownsubstrateinhibitorDetails
DB00679ThioridazinewithdrawnunknownsubstrateDetails
DB00736Esomeprazoleapproved, investigationalunknownsubstrateinhibitorDetails
DB00738PentamidineapprovedunknownsubstrateDetails
DB00794Primidoneapproved, vet_approvedunknownsubstrateinducerDetails
DB00849MethylphenobarbitalapprovedunknownsubstrateinhibitorDetails
DB00863RanitidineapprovedunknownsubstrateDetails
DB00949FelbamateapprovedunknowninhibitorDetails
DB00983Formoterolapproved, investigationalunknownsubstrateDetails
DB01018Guanfacineapproved, investigationalunknownsubstrateDetails
DB01060Amoxicillinapproved, vet_approvedunknownsubstrateDetails
DB01104SertralineapprovedunknownsubstrateinhibitorDetails
DB01124TolbutamideapprovedunknownsubstrateDetails
DB01129Rabeprazoleapproved, investigationalunknownsubstrateinhibitorDetails
DB01131ProguanilapprovedunknownsubstrateDetails
DB01166CilostazolapprovedunknownsubstrateDetails
DB01171MoclobemideapprovedunknownsubstrateinhibitorDetails
DB01174PhenobarbitalapprovedunknownsubstrateinducerDetails
DB01274Arformoterolapproved, investigationalunknownsubstrateDetails
DB01320FosphenytoinapprovedunknownsubstrateinducerDetails
DB01544Flunitrazepamapproved, illicitunknownsubstrateDetails
DB00176Fluvoxamineapproved, investigationalunknowninhibitorDetails
DB00197TroglitazonewithdrawnunknownsubstrateinhibitorDetails
DB00208TiclopidineapprovedunknownsubstrateinhibitorDetails
DB00321AmitriptylineapprovedunknownsubstrateinhibitorDetails
DB00343DiltiazemapprovedunknownsubstrateDetails
DB00455LoratadineapprovedunknowninhibitorinducerDetails
DB00458ImipramineapprovedunknownsubstrateinhibitorDetails
DB00503Ritonavirapproved, investigationalunknowninhibitorinducerDetails
DB00532Mephenytoininvestigational, withdrawnunknownsubstrateinhibitorDetails
DB00586Diclofenacapproved, vet_approvedunknownsubstrateDetails
DB00622NicardipineapprovedunknowninhibitorDetails
DB00625Efavirenzapproved, investigationalunknowninhibitorDetails
DB00745Modafinilapproved, investigationalunknowninhibitorinducerDetails
DB00752TranylcypromineapprovedunknowninhibitorDetails
DB00776OxcarbazepineapprovedunknowninhibitorDetails
DB00927FamotidineapprovedunknownsubstrateDetails
DB00967Desloratadineapproved, investigationalunknowninhibitorDetails
DB01026Ketoconazoleapproved, investigationalunknowninhibitorDetails
DB01041Thalidomideapproved, investigational, withdrawnunknownsubstrateinhibitorDetails
DB01211ClarithromycinapprovedunknownsubstrateinhibitorDetails
DB13179TroleandomycinapprovedunknowninhibitorDetails
DB01424Aminophenazoneapproved, withdrawnunknownsubstrateinhibitorDetails
DB00333MethadoneapprovedunknownsubstrateDetails
DB01065Melatoninapproved, nutraceutical, vet_approvedunknownsubstrateDetails
DB01076AtorvastatinapprovedunknowninhibitorDetails
DB00439CerivastatinwithdrawnunknowninhibitorDetails
DB00227Lovastatinapproved, investigationalunknowninhibitorDetails
DB00641SimvastatinapprovedunknowninhibitorDetails
DB01095FluvastatinapprovedunknowninhibitorDetails
DB00196FluconazoleapprovedunknowninhibitorDetails
DB00619ImatinibapprovedunknownsubstrateDetails
DB00468QuinineapprovedunknownsubstrateinhibitorDetails
DB01142DoxepinapprovedunknownsubstrateDetails
DB01435AntipyrineapprovedunknownsubstrateinhibitorDetails
DB00250Dapsoneapproved, investigationalunknownsubstrateDetails
DB00675TamoxifenapprovedunknownsubstrateDetails
DB05109Trabectedinapproved, investigationalunknownsubstrateDetails
DB01418AcenocoumarolapprovedunknownsubstrateDetails
DB00682WarfarinapprovedunknownsubstrateinhibitorDetails
DB00540NortriptylineapprovedunknownsubstrateDetails
DB00285VenlafaxineapprovedunknownsubstrateDetails
DB00857Terbinafineapproved, investigational, vet_approvedunknownsubstrateDetails
DB00972AzelastineapprovedunknownsubstrateinhibitorDetails
DB01075DiphenhydramineapprovedunknownsubstrateDetails
DB00829Diazepamapproved, illicit, vet_approvedunknownsubstrateinhibitorDetails
DB00446Chloramphenicolapproved, vet_approvedunknownsubstrateinhibitorDetails
DB01242Clomipramineapproved, vet_approvedunknownsubstrateDetails
DB00758Clopidogrelapproved, nutraceuticalunknownsubstrateDetails
DB00531Cyclophosphamideapproved, investigationalunknownsubstrateDetails
DB01355HexobarbitalapprovedunknownsubstrateDetails
DB00571Propranololapproved, investigationalunknownsubstrateDetails
DB00501CimetidineapprovedunknowninhibitorDetails
DB00472Fluoxetineapproved, vet_approvedunknownsubstrateinhibitorDetails
DB01032ProbenecidapprovedunknowninhibitorDetails
DB06403Ambrisentanapproved, investigationalunknownsubstrateDetails
DB01175Escitalopramapproved, investigationalunknownsubstrateDetails
DB06414EtravirineapprovedunknownsubstrateinhibitorDetails
DB01181IfosfamideapprovedunknownsubstrateDetails
DB05246MethsuximideapprovedunknownsubstrateinhibitorDetails
DB00726TrimipramineapprovedunknownsubstrateDetails
DB00357AminoglutethimideapprovedunknowninducerDetails
DB00564Carbamazepineapproved, investigationalunknowninhibitorinducerDetails
DB01601LopinavirapprovedunknowninhibitorinducerDetails
DB01045RifampicinapprovedunknowninducerDetails
DB06413Armodafinilapproved, investigationalunknowninhibitorDetails
DB00705DelavirdineapprovedunknowninhibitorDetails
DB01241GemfibrozilapprovedunknowninhibitorDetails
DB00951IsoniazidapprovedunknowninhibitorDetails
DB06268Sitaxentanapproved, investigational, withdrawnunknowninhibitorDetails
DB00216Eletriptanapproved, investigationalunknownsubstrateDetails
DB00363ClozapineapprovedunknownsubstrateinhibitorDetails
DB00470Dronabinolapproved, illicitunknownsubstrateDetails
DB00425ZolpidemapprovedunknownsubstrateDetails
DB01036Tolterodineapproved, investigationalunknownsubstrateDetails
DB01283Lumiracoxibapproved, investigationalunknownsubstrateDetails
DB00203Sildenafilapproved, investigationalunknownsubstrateinhibitorDetails
DB00672ChlorpropamideapprovedunknownsubstrateDetails
DB01120GliclazideapprovedunknownsubstrateinhibitorDetails
DB01016GlyburideapprovedunknownsubstrateDetails
DB01098RosuvastatinapprovedunknownsubstrateDetails
DB06697ArtemetherapprovedunknownsubstrateinducerDetails
DB00945Acetylsalicylic acidapproved, vet_approvedunknowninducerDetails
DB01118Amiodaroneapproved, investigationalunknownsubstrateDetails
DB00701AmprenavirapprovedunknowninhibitorDetails
DB00673Aprepitantapproved, investigationalunknownsubstrateinhibitorDetails
DB00289AtomoxetineapprovedunknownsubstrateDetails
DB00245BenzatropineapprovedunknownsubstrateDetails
DB04794BifonazoleapprovedunknowninhibitorDetails
DB01558Bromazepamapproved, illicitunknownsubstrateDetails
DB00835BrompheniramineapprovedunknownsubstrateDetails
DB00297Bupivacaineapproved, investigationalunknownsubstrateDetails
DB00921Buprenorphineapproved, illicit, investigational, vet_approvedunknowninhibitorDetails
DB00748CarbinoxamineapprovedunknownsubstrateDetails
DB00091Cyclosporineapproved, investigational, vet_approvedunknowninhibitorDetails
DB00604Cisaprideapproved, investigational, withdrawnunknownsubstrateDetails
DB01559Clotiazepamapproved, illicitunknownsubstrateDetails
DB00257Clotrimazoleapproved, vet_approvedunknowninhibitorDetails
DB00169Cholecalciferolapproved, nutraceuticalunknowninhibitorDetails
DB01151DesipramineapprovedunknownsubstrateinhibitorDetails
DB01234Dexamethasoneapproved, investigational, vet_approvedunknowninducerDetails
DB01191Dexfenfluramineapproved, illicit, withdrawnunknowninhibitorDetails
DB00514DextromethorphanapprovedunknownsubstrateDetails
DB01093Dimethyl sulfoxideapproved, vet_approvedunknowninhibitorDetails
DB00988DopamineapprovedunknownsubstrateDetails
DB00590DoxazosinapprovedunknownsubstrateDetails
DB00783Estradiolapproved, investigational, vet_approvedunknownsubstrateDetails
DB00898EthanolapprovedunknowninhibitorDetails
DB00754EthotoinapprovedunknowninhibitorDetails
DB01628Etoricoxibapproved, investigationalunknowninhibitorDetails
DB00499FlutamideapprovedunknownsubstrateDetails
DB01296GlucosamineapprovedunknownsubstrateDetails
DB00502HaloperidolapprovedunknownsubstrateDetails
DB01050IbuprofenapprovedunknownsubstrateDetails
DB00224IndinavirapprovedunknowninhibitorDetails
DB06738KetobemidoneapprovedunknownsubstrateDetails
DB00678LosartanapprovedunknowninhibitorDetails
DB01043Memantineapproved, investigationalunknowninhibitorDetails
DB00371Meprobamateapproved, illicitunknownsubstrateDetails
DB00703MethazolamideapprovedunknowninhibitorDetails
DB00264Metoprololapproved, investigationalunknownsubstrateDetails
DB01110Miconazoleapproved, investigational, vet_approvedunknowninhibitorDetails
DB00184NicotineapprovedunknownsubstrateDetails
DB06712NilvadipineapprovedunknowninhibitorDetails
DB00717NorethisteroneapprovedunknowninducerDetails
DB00334Olanzapineapproved, investigationalunknowninhibitorDetails
DB00312Pentobarbitalapproved, vet_approvedunknownsubstrateDetails
DB00850PerphenazineapprovedunknownsubstrateDetails
DB00454PethidineapprovedunknownsubstrateDetails
DB03783PhenacetinwithdrawnunknownsubstrateDetails
DB00780PhenelzineapprovedunknowninhibitorDetails
DB00832PhensuximideapprovedunknowninhibitorDetails
DB01100PimozideapprovedunknowninhibitorDetails
DB01132Pioglitazoneapproved, investigationalunknowninhibitorDetails
DB01179PodofiloxapprovedunknownsubstrateDetails
DB01058Praziquantelapproved, vet_approvedunknownsubstrateDetails
DB00635Prednisoneapproved, vet_approvedunknowninducerDetails
DB00818Propofolapproved, investigational, vet_approvedunknownsubstrateDetails
DB01589Quazepamapproved, illicitunknownsubstrateDetails
DB01224QuetiapineapprovedunknownsubstrateDetails
DB00412Rosiglitazoneapproved, investigationalunknowninhibitorDetails
DB01232Saquinavirapproved, investigationalunknowninhibitorDetails
DB01037Selegilineapproved, investigational, vet_approvedunknownsubstrateDetails
DB00259SulfanilamideapprovedunknowninhibitorDetails
DB00966Telmisartanapproved, investigationalunknowninhibitorDetails
DB00624Testosteroneapproved, investigationalunknownsubstrateDetails
DB00763MethimazoleapprovedunknowninhibitorDetails
DB00373TimololapprovedunknownsubstrateDetails
DB01007TioconazoleapprovedunknowninhibitorDetails
DB00214TorasemideapprovedunknowninhibitorDetails
DB00347TrimethadioneapprovedunknownsubstrateDetails
DB00580Valdecoxibinvestigational, withdrawnunknowninhibitorDetails
DB00313Valproic Acidapproved, investigationalunknownsubstrateinhibitorDetails
DB00661VerapamilapprovedunknownsubstrateDetails
DB00549Zafirlukastapproved, investigationalunknowninhibitorDetails
DB00495ZidovudineapprovedunknownsubstrateDetails
DB00909Zonisamideapproved, investigationalunknowninhibitorDetails
DB00398Sorafenibapproved, investigationalunknowninhibitorDetails
DB00932Tipranavirapproved, investigationalunknownsubstrateinhibitorDetails
DB00980Ramelteonapproved, investigationalunknownsubstrateDetails
DB01128BicalutamideapprovedunknowninhibitorDetails
DB01259Lapatinibapproved, investigationalunknownsubstrateDetails
DB01621PipotiazineapprovedunknownsubstrateDetails
DB00918Almotriptanapproved, investigationalunknownsubstrateDetails
DB04920ClevidipineapprovedunknowninhibitorDetails
DB00109Enfuvirtideapproved, investigationalunknownsubstrateDetails
DB00239OxiconazoleapprovedunknownsubstrateDetails
DB00082PegvisomantapprovedunknowninhibitorDetails
DB06204TapentadolapprovedunknownsubstrateDetails
DB06209PrasugrelapprovedyessubstrateDetails
DB04871LorcaserinapprovednosubstrateDetails
DB08864RilpivirineapprovedunknowninhibitorDetails
DB06605ApixabanapprovedunknownsubstrateDetails
DB06626Axitinibapproved, investigationalnosubstrateDetails
DB08828VismodegibapprovedunknowninhibitorDetails
DB08896RegorafenibapprovedunknowninhibitorDetails
DB08899EnzalutamideapprovedunknowninducerDetails
DB08895Tofacitinibapproved, investigationalnosubstrateDetails
DB04938OspemifeneapprovedunknownsubstrateDetails
DB00317Gefitinibapproved, investigationalunknowninhibitorDetails
DB08918LevomilnacipranapprovedunknownsubstrateDetails
DB08932MacitentanapprovednosubstrateDetails
DB08933LuliconazoleapprovednoinhibitorDetails
DB09049NaloxegolapprovedunknowninhibitorDetails
DB00951IsoniazidapprovedunknownDetails
DB09054IdelalisibapprovednoinhibitorDetails
DB09068VortioxetineapprovednosubstrateDetails
DB09280LumacaftorapprovednoinducerDetails
DB09570IxazomibapprovedunknownsubstrateDetails
DB06176Romidepsinapproved, investigationalunknownsubstrateDetails
DB06412Oxymetholoneapproved, illicitunknowninhibitorDetails
DB09119Eslicarbazepine acetateapprovedyesinhibitorDetails
DB06789Hydroxyprogesterone caproateapprovedunknowninducerDetails
DB05812AbirateroneapprovedunknowninhibitorDetails
DB09118StiripentolapprovedunknowninhibitorDetails
DB06595MidostaurinapprovedunknowninhibitorinducerDetails
DB05541Brivaracetamapproved, investigationalnosubstrateDetails
DB05351DexlansoprazoleapprovedunknownsubstrateinhibitorDetails
DB01685TopiroxostatapprovedunknowninhibitorDetails
DB09120ZucapsaicinapprovedunknowninhibitorDetails
DB09198LobeglitazoneapprovednoinhibitorDetails
DB09167DosulepinapprovedunknowninhibitorDetails
DB09166EtizolamapprovedunknownsubstrateDetails
DB11614RupatadineapprovednosubstrateDetails
DB12319Benzbromaroneinvestigational, withdrawnunknowninhibitorDetails
DB09238ManidipineapprovedunknowninhibitorDetails