Tripartite terminase subunit 2
Details
- Name
- Tripartite terminase subunit 2
- Synonyms
- Not Available
- Gene Name
- TRM2
- Organism
- Human Cytomegalovirus
- Amino acid sequence
>lcl|BSEQ0051320|Tripartite terminase subunit 2 MSWAKQRVPFLDDDDGEEENDVQDDVDSPVPTRPLVIDEDAEPAAGTSGGLEGGGGDDED GEDGHALPDLDDDLLLQFEPMLPRVYDLLLPSLDARLNFVNAGQKYAAFLKYVHGDCATC SHGEILREKTQLLTAIVSKLMDINGILEGKDEPAPGK
- Number of residues
- 157
- Molecular Weight
- 16977.55
- Theoretical pI
- Not Available
- GO Classification
- Processesviral DNA genome packaging / viral release from host cellComponentshost cell nucleus
- General Function
- Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM3 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid.
- Specific Function
- Not Available
- Pfam Domain Function
- Herpes_UL33 (PF03581)
- Transmembrane Regions
- Not Available
- Cellular Location
- Host nucleus
- Gene sequence
>lcl|BSEQ0051321|Tripartite terminase subunit 2 (TRM2) ATGTCCTGGGCTAAGCAGCGGGTGCCGTTTCTGGACGATGACGACGGAGAGGAGGAAAAC GACGTGCAGGATGACGTGGATTCTCCGGTGCCGACGCGACCGCTGGTGATCGACGAGGAC GCGGAGCCCGCGGCTGGTACGAGCGGTGGGCTCGAGGGGGGAGGTGGTGACGACGAGGAC GGTGAAGACGGACACGCGCTACCCGATCTTGACGACGATCTGCTATTACAGTTCGAGCCG ATGCTGCCGCGCGTCTACGATCTGTTGCTGCCCTCTCTGGACGCGCGCTTAAATTTCGTG AACGCGGGTCAGAAGTACGCCGCCTTCCTCAAGTACGTGCACGGCGACTGCGCGACCTGC AGTCACGGAGAGATCCTCCGTGAGAAGACGCAACTATTAACGGCGATCGTCAGCAAGCTC ATGGACATTAACGGAATCCTGGAGGGAAAAGACGAGCCGGCGCCGGGTAAATAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID F5HGI9 UniProtKB Entry Name TRM2_HCMVM - General References
- Dolan A, Cunningham C, Hector RD, Hassan-Walker AF, Lee L, Addison C, Dargan DJ, McGeoch DJ, Gatherer D, Emery VC, Griffiths PD, Sinzger C, McSharry BP, Wilkinson GW, Davison AJ: Genetic content of wild-type human cytomegalovirus. J Gen Virol. 2004 May;85(Pt 5):1301-12. [Article]