Colicin-E3
Details
- Name
- Colicin-E3
- Synonyms
- 3.1.-.-
- Colicin-E3 A chain
- Ribonuclease
- Gene Name
- ceaC
- Organism
- Escherichia coli
- Amino acid sequence
>lcl|BSEQ0012901|Colicin-E3 MSGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGS GHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISAGALSAAIADIM AALKGPFKFGLWGVALYGVLPSQIAKDDPNMMSKIVTSLPADDITESPVSSLPLDKATVN VNVRVVDDVKDERQNISVVSGVPMSVPVVDAKPTERPGVFTASIPGAPVLNISVNNSTPA VQTLSPGVTNNTDKDVRPAGFTQGGNTRDAVIRFPKDSGHNAVYVSVSDVLSPDQVKQRQ DEENRRQQEWDATHPVEAAERNYERARAELNQANEDVARNQERQAKAVQVYNSRKSELDA ANKTLADAIAEIKQFNRFAHDPMAGGHRMWQMAGLKAQRAQTDVNNKQAAFDAAAKEKSD ADAALSSAMESRKKKEDKKRSAENNLNDEKNKPRKGFKDYGHDYHPAPKTENIKGLGDLK PGIPKTPKQNGGGKRKRWTGDKGRKIYEWDSQHGELEGYRASDGQHLGSFDPKTGNQLKG PDPKRNIKKYL
- Number of residues
- 551
- Molecular Weight
- 57962.76
- Theoretical pI
- 9.65
- GO Classification
- Functionsendonuclease activity / ribosome binding / RNA bindingProcessescytolysis / defense response to bacterium / pathogenesisComponentsextrachromosomal circular DNA
- General Function
- Rna binding
- Specific Function
- Inactivates ribosomes by hydrolyzing 16S RNA in 30S ribosomes at a specific site.Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria.
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasmic
- Gene sequence
>lcl|BSEQ0007929|1656 bp ATGAGCGGTGGCGATGGACGCGGCCATAACACGGGCGCGCATAGCACAAGTGGTAACATT AATGGTGGCCCGACCGGGCTTGGTGTAGGTGGTGGTGCTTCTGATGGCTCCGGATGGAGT TCGGAAAATAACCCGTGGGGTGGTGGTTCCGGTAGCGGCATTCACTGGGGTGGTGGTTCC GGTCATGGTAATGGCGGGGGGAATGGTAATTCCGGTGGTGGTTCGGGAACAGGCGGTAAT CTGTCAGCAGTAGCTGCGCCAGTGGCATTTGGTTTTCCGGCACTTTCCACTCCAGGAGCT GGCGGTCTGGCGGTCAGTATTTCAGCGGGAGCATTATCGGCAGCTATTGCTGATATTATG GCTGCCCTGAAAGGACCGTTTAAATTTGGTCTTTGGGGGGTGGCTTTATATGGTGTATTG CCATCACAAATAGCGAAAGATGACCCCAATATGATGTCAAAGATTGTGACGTCATTACCC GCAGATGATATTACTGAATCACCTGTCAGTTCATTACCTCTCGATAAGGCAACAGTAAAC GTAAATGTTCGTGTTGTTGATGATGTAAAAGACGAGCGACAGAATATTTCGGTTGTTTCA GGTGTTCCGATGAGTGTTCCGGTGGTTGATGCAAAACCTACCGAACGTCCGGGTGTTTTT ACGGCATCAATTCCAGGTGCACCTGTTCTGAATATTTCAGTTAATAACAGTACGCCAGCA GTACAGACATTAAGCCCAGGTGTTACAAATAATACTGATAAGGATGTTCGCCCGGCAGGA TTTACTCAGGGTGGTAATACCAGGGATGCAGTTATTCGATTCCCGAAGGACAGCGGTCAT AATGCCGTATATGTTTCAGTGAGTGATGTTCTTAGCCCTGACCAGGTAAAACAACGTCAA GATGAAGAAAATCGCCGTCAGCAGGAATGGGATGCTACGCATCCGGTTGAAGCGGCTGAG CGAAATTATGAACGCGCGCGTGCAGAGCTGAATCAGGCAAATGAAGATGTTGCCAGAAAT CAGGAGCGACAGGCTAAAGCTGTTCAGGTTTATAATTCGCGTAAAAGCGAACTTGATGCA GCGAATAAAACTCTTGCTGATGCAATAGCTGAAATAAAACAATTTAATCGATTTGCCCAT GACCCAATGGCTGGCGGTCACAGAATGTGGCAAATGGCCGGGCTTAAAGCCCAGCGGGCG CAGACGGATGTAAATAATAAGCAGGCTGCATTTGATGCTGCTGCAAAAGAGAAGTCAGAT GCTGATGCTGCATTGAGTTCTGCTATGGAAAGCAGGAAGAAGAAAGAAGATAAGAAAAGG AGTGCTGAAAATAATTTAAACGATGAAAAGAATAAGCCCAGAAAAGGTTTTAAAGATTAC GGGCATGATTATCATCCAGCTCCGAAAACTGAGAATATTAAAGGGCTTGGTGATCTTAAG CCTGGGATACCAAAAACACCAAAGCAGAATGGTGGTGGAAAACGCAAGCGCTGGACTGGA GATAAAGGGCGTAAGATTTATGAGTGGGATTCTCAGCATGGTGAGCTTGAGGGGTATCGT GCCAGTGATGGTCAGCATCTTGGCTCATTTGACCCTAAAACAGGCAATCAGTTGAAAGGT CCAGATCCGAAACGAAATATCAAGAAATATCTTTGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P00646 UniProtKB Entry Name CEA3_ECOLX GenBank Protein ID 144390 GenBank Gene ID J01574 - General References
- Masaki H, Ohta T: Colicin E3 and its immunity genes. J Mol Biol. 1985 Mar 20;182(2):217-27. [Article]
- Lau PC, Rowsome RW, Zuker M, Visentin LP: Comparative nucleotide sequences encoding the immunity proteins and the carboxyl-terminal peptides of colicins E2 and E3. Nucleic Acids Res. 1984 Nov 26;12(22):8733-45. [Article]
- Mock M, Miyada CG, Gunsalus RP: Nucleotide sequence for the catalytic domain of colicin E3 and its immunity protein. Evidence for a third gene overlapping colicin. Nucleic Acids Res. 1983 Jun 11;11(11):3547-57. [Article]
- Masaki H, Ohta T: A plasmid region encoding the active fragment and the inhibitor protein of colicin E3--CA38. FEBS Lett. 1982 Nov 22;149(1):129-32. [Article]
- Suzuki K, Imahori K: Amino acid sequence of an active fragment (T2A) of colicin E3. J Biochem. 1978 Nov;84(5):1031-9. [Article]