Keratin, type II cytoskeletal 7
Details
- Name
- Keratin, type II cytoskeletal 7
- Synonyms
- CK-7
- Cytokeratin-7
- K7
- Keratin-7
- Sarcolectin
- SCL
- Type-II keratin Kb7
- Gene Name
- KRT7
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0037209|Keratin, type II cytoskeletal 7 MSIHFSSPVFTSRSAAFSGRGAQVRLSSARPGGLGSSSLYGLGASRPRVAVRSAYGGPVG AGIREVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLE TKWTLLQEQKSAKSSRLPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKY EDEINHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQI SDTSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDD LRNTRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAA LQRGKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNSTG GSSSGGGIGLTLGGTMGSNALSFSSSAGPGLLKAYSIRTASASRRSARD
- Number of residues
- 469
- Molecular Weight
- 51385.11
- Theoretical pI
- 5.23
- GO Classification
- Functionsstructural molecule activityProcessesviral processComponentscytoplasm / extracellular exosome / intermediate filament / keratin filament / nucleus
- General Function
- Structural molecule activity
- Specific Function
- Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasm
- Gene sequence
>lcl|BSEQ0011759|Keratin, type II cytoskeletal 7 (KRT7) ATGTCCATCCACTTCAGCTCCCCGGTATTCACCTCGCGCTCAGCCGCCTTCTCGGGCCGC GGCGCCCAGGTGCGCCTGAGCTCCGCTCGCCCCGGCGGCCTTGGCAGCAGCAGCCTCTAC GGCCTCGGCGCCTCACGGCCGCGCGTGGCCGTGCGCTCTGCCTATGGGGGCCCGGTGGGC GCCGGCATCCGCGAGGTCACCATTAACCAGAGCCTGCTGGCCCCGCTGCGGCTGGACGCC GACCCCTCCCTCCAGCGGGTGCGCCAGGAGGAGAGCGAGCAGATCAAGACCCTCAACAAC AAGTTTGCCTCCTTCATCGACAAGGTGCGGTTTCTGGAGCAGCAGAACAAGCTGCTGGAG ACCAAGTGGACGCTGCTGCAGGAGCAGAAGTCGGCCAAGAGCAGCCGCCTCCCAGACATC TTTGAGGCCCAGATTGCTGGCCTTCGGGGTCAGCTTGAGGCACTGCAGGTGGATGGGGGC CGCCTGGAGGCGGAGCTGCGGAGCATGCAGGATGTGGTGGAGGACTTCAAGAATAAGTAC GAAGATGAAATTAACCACCGCACAGCTGCTGAGAATGAGTTTGTGGTGCTGAAGAAGGAT GTGGATGCTGCCTACATGAGCAAGGTGGAGCTGGAGGCCAAGGTGGATGCCCTGAATGAT GAGATCAACTTCCTCAGGACCCTCAATGAGACGGAGTTGACAGAGCTGCAGTCCCAGATC TCCGACACATCTGTGGTGCTGTCCATGGACAACAGTCGCTCCCTGGACCTGGACGGCATC ATCGCTGAGGTCAAGGCGCAGTATGAGGAGATGGCCAAATGCAGCCGGGCTGAGGCTGAA GCCTGGTACCAGACCAAGTTTGAGACCCTCCAGGCCCAGGCTGGGAAGCATGGGGACGAC CTCCGGAATACCCGGAATGAGATTTCAGAGATGAACCGGGCCATCCAGAGGCTGCAGGCT GAGATCGACAACATCAAGAACCAGCGTGCCAAGTTGGAGGCCGCCATTGCCGAGGCTGAG GAGCGTGGGGAGCTGGCGCTCAAGGATGCTCGTGCCAAGCAGGAGGAGCTGGAAGCCGCC CTGCAGCGGGGCAAGCAGGATATGGCACGGCAGCTGCGTGAGTACCAGGAACTCATGAGC GTGAAGCTGGCCCTGGACATCGAGATCGCCACCTACCGCAAGCTGCTGGAGGGCGAGGAG AGCCGGTTGGCTGGAGATGGAGTGGGAGCCGTGAATATCTCTGTGATGAATTCCACTGGT GGCAGTAGCAGTGGCGGTGGCATTGGGCTGACCCTCGGGGGAACCATGGGCAGCAATGCC CTGAGCTTCTCCAGCAGTGCGGGTCCTGGGCTCCTGAAGGCTTATTCCATCCGGACCGCA TCCGCCAGTCGCAGGAGTGCCCGCGACTGA
- Chromosome Location
- 12
- Locus
- 12q12-q13
- External Identifiers
Resource Link UniProtKB ID P08729 UniProtKB Entry Name K2C7_HUMAN GenBank Gene ID AJ238246 GenAtlas ID KRT7 HGNC ID HGNC:6445 - General References
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