Flavodoxin

Details

Name

Flavodoxin

Synonyms

Not Available

Gene Name

isiB

Organism

Synechococcus elongatus (strain PCC 7942)

Amino acid sequence

>lcl|BSEQ0016962|Flavodoxin
MAKIGLFYGTQTGVTQTIAESIQQEFGGESIVDLNDIANADASDLNAYDYLIIGCPTWNV
GELQSDWEGIYDDLDSVNFQGKKVAYFGAGDQVGYSDNFQDAMGILEEKISSLGSQTVGY
WPIEGYDFNESKAVRNNQFVGLAIDEDNQPDLTKNRIKTWVSQLKSEFGL

Number of residues

170

Molecular Weight

18777.495

Theoretical pI

3.78

GO Classification

Functions

electron carrier activity / FMN binding

Processes

oxidation-reduction process

General Function

Fmn binding

Specific Function

Low-potential electron donor to a number of redox enzymes.

Pfam Domain Function

• Flavodoxin_1 (PF00258)

Transmembrane Regions

Not Available

Cellular Location

Not Available

Gene sequence

>lcl|BSEQ0016963|Flavodoxin (isiB)
ATGGCCAAAATTGGCTTATTCTACGGAACTCAAACAGGCGTTACCCAAACTATTGCTGAA
TCGATTCAACAAGAGTTTGGCGGTGAAAGTATTGTTGACCTCAATGATATTGCGAATGCT
GATGCCAGTGATTTAAATGCCTATGATTATTTAATTATCGGTTGTCCTACTTGGAATGTT
GGTGAACTGCAAAGTGACTGGGAAGGAATCTATGATGATTTAGACTCAGTCAACTTTCAA
GGGAAGAAAGTTGCCTACTTTGGAGCGGGTGATCAAGTAGGCTATTCCGATAACTTTCAG
GATGCTATGGGCATTCTAGAAGAAAAAATTAGCTCTTTAGGTAGTCAAACAGTTGGCTAT
TGGCCTATTGAAGGCTATGACTTCAATGAGTCAAAAGCTGTACGCAATAATCAGTTTGTT
GGTTTAGCAATTGATGAAGACAATCAACCTGATCTCACAAAGAATCGAATTAAGACTTGG
GTCAGCCAGCTAAAGTCAGAGTTCGGTCTTTAA

Chromosome Location

Not Available

Locus

Not Available

External Identifiers

Resource	Link
UniProtKB ID	P10340
UniProtKB Entry Name	FLAV_SYNE7
GenBank Gene ID	M19116

General References

1. Laudenbach DE, Reith ME, Straus NA: Isolation, sequence analysis, and transcriptional studies of the flavodoxin gene from Anacystis nidulans R2. J Bacteriol. 1988 Jan;170(1):258-65. [Article]
2. Smith WW, Pattridge KA, Ludwig ML, Petsko GA, Tsernoglou D, Tanaka M, Yasunobu KT: Structure of oxidized flavodoxin from Anacystis nidulans. J Mol Biol. 1983 Apr 25;165(4):737-53. [Article]
3. Drennan CL, Pattridge KA, Weber CH, Metzger AL, Hoover DM, Ludwig ML: Refined structures of oxidized flavodoxin from Anacystis nidulans. J Mol Biol. 1999 Dec 3;294(3):711-24. [Article]
4. Hoover DM, Drennan CL, Metzger AL, Osborne C, Weber CH, Pattridge KA, Ludwig ML: Comparisons of wild-type and mutant flavodoxins from Anacystis nidulans. Structural determinants of the redox potentials. J Mol Biol. 1999 Dec 3;294(3):725-43. [Article]
5. Clubb RT, Thanabal V, Osborne C, Wagner G: 1H and 15N resonance assignments of oxidized flavodoxin from Anacystis nidulans with 3D NMR. Biochemistry. 1991 Aug 6;30(31):7718-30. [Article]

Drug Relations

Drug Relations

DrugBank ID	Name	Drug group	Pharmacological action?	Actions	Details
DB03247	Flavin mononucleotide	approved, investigational	unknown		Details